Apparatus and method for image reconstruction using feature-aware deep learning

    公开(公告)号:US11315221B2

    公开(公告)日:2022-04-26

    申请号:US16372174

    申请日:2019-04-01

    Abstract: A method and apparatus is provided to perform medical imaging in which feature-aware reconstruction is performed using a neural network. The neural network is trained to perform feature-aware reconstruction by using a training dataset in which the target data has a spatially-dependent degree of denoising and artifact reduction based on the features represented in the image. For example, a target image can be generated by reconstructing multiple images, each using a respective regularization parameter that is optimized for a different anatomy/organ (e.g., abdomen, lung, bone, etc.). And a target image can be generated using artifact reduction method (e.g. metal artifact reduction, aliasing artifact reduction, etc.). Then respective regions/features (e.g., abdomen, lung, and bone, artifact free, regions/features) can be extracted from the corresponding images and combined into a single combined image, which is used as the target data to train the neural network.

    Method and apparatus for scatter estimation in positron emission tomography

    公开(公告)号:US11276209B2

    公开(公告)日:2022-03-15

    申请号:US16860425

    申请日:2020-04-28

    Abstract: The present disclosure relates to an apparatus for estimating scatter in positron emission tomography, comprising processing circuitry configured to acquire an emission map and an attenuation map, each representing an initial image reconstruction of a positron emission tomography scan, calculate, using a radiative transfer equation (RTE) method, a scatter source map of a subject of the positron emission tomography scan based on the emission map and the attenuation map, estimate, using the RTE method and based on the emission map, the attenuation map, and the scatter source map, scatter, and perform an iterative image reconstruction of the positron emission tomography scan based on the estimated scatter and raw data from the positron emission tomography scan of the subject.

    Apparatus and method for sinogram restoration in computed tomography (CT) using adaptive filtering with deep learning (DL)

    公开(公告)号:US11176428B2

    公开(公告)日:2021-11-16

    申请号:US16372206

    申请日:2019-04-01

    Abstract: A method and apparatus is provided to reduce the noise in medical imaging by training a deep learning (DL) network to select the optimal parameters for a convolution kernel of an adaptive filter that is applied in the data domain. For example, in X-ray computed tomography (CT) the adaptive filter applies smoothing to a sinogram, and the optimal amount of the smoothing and orientation of the kernel (e.g., a bivariate Gaussian) can be determined on a pixel-by-pixel basis by applying a noisy sinogram to the DL network, which outputs the parameters of the filter (e.g., the orientation and variances of the Gaussian kernel). The DL network is trained using a training data set including target data (e.g., the gold standard) and input data. The input data can be sinograms generated by a low-dose CT scan, and the target data generated by a high-dose CT scan.

    Apparatus and method for artifact detection and correction using deep learning

    公开(公告)号:US11100684B2

    公开(公告)日:2021-08-24

    申请号:US16509408

    申请日:2019-07-11

    Abstract: A method and apparatus are provided that use deep learning (DL) networks to reduce noise and artifacts in reconstructed computed tomography (CT), positron emission tomography (PET), and magnetic resonance imaging (MRI) images. DL networks are used in both the sinogram and image domains. In each domain, a detection network is used to (i) determine if particular types of artifacts are exhibited (e.g., beam-hardening artifact, ring, motion, metal, photon-starvation, windmill, zebra, partial-volume, cupping, truncation, streak artifact, and/or shadowing artifacts), (ii) determine whether the detected artifact can be corrected through a changed scan protocol or image-processing techniques, and (iii) determine whether the detected artifacts are fatal, in which case the scan is stopped short of completion. When the artifacts can be corrected, corrective measures are taken through a changed scan protocol or through image processing to reduce the artifacts (e.g., convolutional neural network can be trained to perform the image processing).

    Method and apparatus for acceleration of iterative reconstruction of a computed tomography image

    公开(公告)号:US11087508B2

    公开(公告)日:2021-08-10

    申请号:US16206922

    申请日:2018-11-30

    Abstract: A method and apparatus is provided to reconstruct a computed tomography image using iterative reconstruction (IR) that is accelerated using various combinations of ordered subsets, conjugate gradient, preconditioning, resetting/restarting, and/or gradient approximation techniques. For example, when restarting criteria are satisfied the IR algorithm can be reset by setting conjugate-gradient parameters to initial values and/or by changing the number of ordered subsets. The IR algorithm can be accelerated by approximately calculating the gradients, by using a diagonal or Fourier preconditioner, and by selectively updating the preconditioner based on the regularization function. The update direction and step size can be calculated using the preconditioner and a surrogate function, which is not necessarily separable.

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