公开(公告)号：US07942528B2

公开(公告)日：2011-05-17

申请号：US12559640

申请日：2009-09-15

申请人： Takuya Hara

发明人： Takuya Hara

IPC分类号： A61B3/02

CPC分类号： A61B3/024 ,  A61B3/0091 ,  A61B3/152

摘要： A perimeter has fixation state judging means for individually judging a fixation state of an examinee in connection with each presented stimulus, and the fixation state judging means individually judges the fixation state whenever the stimulus is presented. Even if defective fixation is judged, retest is conducted on only a point where the stimulus was presented, which was judged to be defective fixation. Then, examiner's burden and examinee's burden can be lightened, the test time can be made shorter and test efficiency can be improved in comparison with a case where the whole test is retried from the first as a conventional way.

摘要翻译： 周边具有用于单独地判断与每个呈现的刺激相关的受检者的固定状态的固定状态判断装置，并且每当呈现刺激时，固定状态判断装置单独地判断固定状态。 即使判定有缺陷的固定，只能在刺激呈现的点进行重新测试，这被认为是固定不良。 然后，与以往的方式从第一次重试的情况相比，可以减轻检查员的负担和考生的负担，可以缩短测试时间，提高测试效率。

公开(公告)号：US20100120844A1

公开(公告)日：2010-05-13

申请号：US12531318

申请日：2008-04-03

申请人： Seiichi Sato ,  Junya Tagashira ,  Shunji Takemura ,  Yoshiharu Miyake ,  Tetsuya Ishikawa ,  Toshiharu Arai ,  Takahiro Ito ,  Takuya Hara

发明人： Seiichi Sato ,  Junya Tagashira ,  Shunji Takemura ,  Yoshiharu Miyake ,  Tetsuya Ishikawa ,  Toshiharu Arai ,  Takahiro Ito ,  Takuya Hara

IPC分类号： A61K31/4709 ,  C07D401/02 ,  C07D217/18 ,  A61K31/47 ,  A61P11/06 ,  A61P31/18 ,  A61P37/06 ,  A61P1/00

CPC分类号： C07D217/04 ,  A61K31/472 ,  A61K31/4725 ,  C07D217/02 ,  C07D217/14 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D405/12 ,  C07D409/12 ,  C07D409/14 ,  C07D417/12

摘要： The present invention relates a specific tetrahydroisoquinoline compound which is useful as a chemokine receptor type 3 (CCR3) antagonist, and a pharmaceutical composition comprising the same as an active ingredient. The tetrahydroisoquinoline compound of the present invention is useful for the treatment or prevention of a disease in which CCR3 participates.

摘要翻译： 本发明涉及可用作3型趋化因子受体（CCR3）拮抗剂的特定四氢异喹啉化合物，以及包含其作为活性成分的药物组合物。 本发明的四氢异喹啉化合物可用于治疗或预防CCR3参与的疾病。

公开(公告)号：US20090231543A1

公开(公告)日：2009-09-17

申请号：US12283637

申请日：2008-09-12

申请人： Takuya Hara ,  Kazunori Matsumura ,  Tatsuya Fujii ,  Masaharu Mizuochi

发明人： Takuya Hara ,  Kazunori Matsumura ,  Tatsuya Fujii ,  Masaharu Mizuochi

IPC分类号： A61B3/14

CPC分类号： A61B5/0496

摘要： A stimulus light from a stimulus light source is projected to the retina of an ocular fundus under examination to stimulate the retina in localized fashion to generate a bioelectric signal from the retina. The stimulus light source is mounted on a movable block, and an operating lever is used to move the stimulus light source to change the stimulus light on the retina. The size of the stimulus light can also be varied using a panel having a plurality of openings with different diameters for allowing the stimulus light to pass through. This assures a reliable local ERG examination because the bioelectrical signal can be produced in a wider area of the retina. The operating lever is further fixed by inserting a cap to keep the projected stimulus light unchanged. This allows the burden on the examiner to be reduced remarkably, assuring a reliable local ERG examination.

摘要翻译： 来自刺激光源的刺激光被投射到正在检查的眼底视网膜，以局部方式刺激视网膜以从视网膜产生生物电信号。 刺激光源安装在可动块上，操作杆用于移动刺激光源以改变视网膜上的刺激光。 刺激光的尺寸也可以使用具有不同直径的多个开口的面板来改变，以允许刺激光通过。 这确保了可靠的局部ERG检查，因为生物电信号可以在视网膜的更广的区域中产生。 通过插入盖子来进一步固定操作杆，以保持投影的刺激光线不变。 这样可以显着降低审查员的负担，确保当地的ERG检查可靠。

公开(公告)号：US06685321B2

公开(公告)日：2004-02-03

申请号：US10090063

申请日：2002-03-01

申请人： Yoshikatsu Suzumura ,  Takuya Hara

发明人： Yoshikatsu Suzumura ,  Takuya Hara

IPC分类号： A61B302

CPC分类号： A61B3/024

摘要： A perimeter has an optical projection system that projects a target spot on the inside surface of a visual field dome. The position at which the target spot is projected is controlled electronically. Input devices are used to input control information to control the target spot projection position and to record patient response information. A display means provides feedback display of the control information and patient response information, and also functions as an input screen via which the control and response information is input.

摘要翻译： 一个周边有一个光学投影系统，将目标点投射在视场圆顶的内表面上。 投射目标点的位置是电子控制的。 输入设备用于输入控制信息以控制目标点投影位置并记录病人的应答信息。 显示装置提供控制信息和患者响应信息的反馈显示，并且还用作输入控制和响应信息的输入屏幕。

公开(公告)号：US09089260B2

公开(公告)日：2015-07-28

申请号：US13817603

申请日：2011-08-08

申请人： Takuya Hara

发明人： Takuya Hara

IPC分类号： A61B3/10 ,  A61B3/00 ,  A61B3/14 ,  F21V21/28

CPC分类号： A61B3/0091 ,  A61B3/0075 ,  A61B3/14 ,  F21V21/28

摘要： [Problem] To increase, compared to conventional devices, the range of motion of the light emitter (fixation lamp) in an external fixation lamp for an ophthalmological instrument and allow movement of the light emitter to arbitrary positions.[Solution] The fixation lamp (1) has a first arm (A1), which supports a light emitter (2) and is supported by a second arm (A2) via a first joint (C1), and is configured so that the first arm (A1) is able to revolve around at least two axes of revolution (E1, E2) by means of the first joint (C1) and said axes of rotation (E1, E2) are not disposed on the same line. Thereby, the range in which the light emitter (2) can be moved can be increased compared to conventional devices and the light emitter can be moved to an arbitrary position in an arbitrary direction.

摘要翻译： [问题]与传统装置相比，增加用于眼科仪器的外部固定灯中的光发射器（固定灯）的运动范围并允许光发射器移动到任意位置。 [解决方案]固定灯（1）具有第一臂（A1），其支撑发光体（2），并且经由第一接头（C1）由第二臂（A2）支撑，并且被构造成使得第一 臂（A1）能够通过第一接头（C1）绕至少两个旋转轴线（E1，E2）旋转，并且所述旋转轴线（E1，E2）不设置在同一直线上。 由此，与以往的装置相比，可以使发光体（2）能够移动的范围增大，能够使发光体向任意方向移动到任意位置。

公开(公告)号：US08326138B2

公开(公告)日：2012-12-04

申请号：US13067475

申请日：2011-06-03

申请人： Masayuki Yoshii ,  Takuya Hara ,  Nobuhisa Koike

发明人： Masayuki Yoshii ,  Takuya Hara ,  Nobuhisa Koike

IPC分类号： G03B3/00 ,  G02B7/28

CPC分类号： G02B7/282 ,  G03B7/02 ,  G03B13/36 ,  G03B15/05 ,  G03B17/02 ,  G03B19/02 ,  G03B19/12 ,  G03B2215/0507

摘要： An imaging apparatus includes an apparatus body having an outer casing, at least a shutter mechanism and an imaging device placed inside the outer casing, an opening formed in the outer casing, and a storage space and a placement space defined inside the outer casing and communicating with the opening and the storage space, respectively, a strobe unit having a lid part and a light-emitting part and connected to the apparatus body so as to be movable between close and open positions, a sensor unit placed in the placement space and having an autofocus sensor and a sensor adjusting part having plural adjusting screws, and a mirror placed inside the outer casing to reflect part of incident light toward the autofocus sensor. When the strobe unit is moved to the open position, the storage space is defined as an adjustment space into which an adjustment jig can be inserted.

摘要翻译： 一种成像装置，包括具有外壳，至少设置有挡板机构和放置在外壳内的成像装置的装置主体，形成在外壳中的开口，以及限定在外壳内部并且连通的存放空间和放置空间 具有开口和存储空间的闪光灯单元具有盖部和发光部，并且连接到装置主体，以在关闭位置和打开位置之间移动;传感器单元，放置在放置空间中，并具有 具有多个调节螺钉的自动聚焦传感器和传感器调节部件，以及放置在外壳内的反射镜，以将入射光的一部分反射到自动聚焦传感器。 当闪光灯单元移动到打开位置时，存储空间被定义为可以插入调节夹具的调整空间。

公开(公告)号：US20120003745A1

公开(公告)日：2012-01-05

申请号：US13256427

申请日：2010-03-12

申请人： Katsumi Yabusaki ,  Takuya Hara ,  Yuka Sugiura

发明人： Katsumi Yabusaki ,  Takuya Hara ,  Yuka Sugiura

IPC分类号： G01N33/00 ,  G01N27/00

CPC分类号： G01N33/579 ,  G01N21/82 ,  Y10T436/143333

摘要： When assessing the start time of the limulus reaction between biogenous biologically active substances and LAL and using the reaction start time to determine the concentration of the biogenous biologically active substances, in order to exclude the influence of progressive changes which occur regardless of the conditions of the limulus reaction, the strength of transmitted light or scattered light in the liquid mixture of the measurement sample and LAL is detected, the variation (delta) in the transmittance or number of gel particles is acquired at set intervals, and the time when the variation (delta) crosses a threshold value is taken as the reaction start time. Furthermore, the time intervals when acquiring the abovementioned delta are not uniform, and either change over time from the start of measurement as defined by a time function, or multiple sequences with differing time intervals are prepared in advance.

摘要翻译： 当评估生物生物活性物质与LAL之间的鲎反应的开始时间并且使用反应开始时间来确定生物生物活性物质的浓度时，为了排除发生的进行性变化的影响，而不管 鲎反应检测到测量样品和LAL的液体混合物中的透射光或散射光的强度，凝胶颗粒的透射率或数量的变化（delta）以设定的间隔获得，并且变化（ delta）跨越阈值作为反应开始时间。 此外，获取上述增量的时间间隔是不均匀的，并且随着时间函数定义的测量开始的时间而改变，或者预先准备具有不同时间间隔的多个序列。

公开(公告)号：US08002479B2

公开(公告)日：2011-08-23

申请号：US12661813

申请日：2010-03-24

申请人： Toshiaki Ueda ,  Hideo Fukumoto ,  Takuya Hara ,  Yoshinori Sugiyama ,  Shigekazu Inaba

发明人： Toshiaki Ueda ,  Hideo Fukumoto ,  Takuya Hara ,  Yoshinori Sugiyama ,  Shigekazu Inaba

IPC分类号： G03B19/12

CPC分类号： G03B17/02

摘要： An imaging apparatus includes: a mount fixing member to which a lens mount is fixed; a connected body obtained by integrally connecting a plurality of constituent units including a battery holder unit, the plurality of constituent units provided around the mount fixing member; and a front member fixed to the connected body and integrated therewith, wherein the mount fixing member is fixed to the front member.

摘要翻译： 一种成像装置，包括：固定有透镜座的安装固定构件; 通过一体地连接包括电池保持器单元的多个构成单元，设置在安装固定构件周围的多个构成单元而获得的连接体; 以及固定到所述连接体并与其成一体的前部构件，其中所述安装固定构件固定到所述前部构件。

公开(公告)号：USD709199S1

公开(公告)日：2014-07-15

申请号：US29392570

申请日：2011-05-24

申请人： Naoki Kambe ,  Takuya Hara ,  Atsushi Kakuuchi

设计人： Naoki Kambe ,  Takuya Hara ,  Atsushi Kakuuchi

公开(公告)号：US20130069973A1

公开(公告)日：2013-03-21

申请号：US13641177

申请日：2011-04-12

申请人： Kazuo Ichikawa ,  Kiyoshi Tanaka ,  Yoshiki Tanaka ,  Takuya Hara

发明人： Kazuo Ichikawa ,  Kiyoshi Tanaka ,  Yoshiki Tanaka ,  Takuya Hara

IPC分类号： G09G5/02

CPC分类号： G09G5/02 ,  A61B3/032 ,  A61B3/066 ,  G06T11/00

摘要： A color perception test has a color matching processor that executes a color matching processing on a color monitor, and an image display controller that displays two or more images for color perception test in order on the color monitor on which the color matching processing was done. When displaying each image for color perception test, a color perception test is done in a state that one of its hue, brightness, saturation and display time is changed and the other elements are fixed. Since the color perception tester has the color matching processor, colors of the image are not changed with passage of time different from color printed one, and correct test can be done thereby. If the test is periodically done on some examinee, a degree of decreasing color perception function by aging can be exactly known.

摘要翻译： 颜色感知测试具有在颜色监视器上执行颜色匹配处理的颜色匹配处理器，以及在进行颜色匹配处理的彩色监视器上依次显示用于颜色感知测试的两个或更多个图像的图像显示控制器。 当显示每个图像的颜色感知测试时，颜色感知测试在其色调，亮度，饱和度和显示时间之一改变并且其他元素是固定的状态下完成。 由于颜色感知测试仪具有颜色匹配处理器，所以图像的颜色不会随着时间的推移而不同于彩色印刷，因此可以进行正确的测试。 如果在一些考生周期性地进行测试，则可以准确地知道通过老化降低颜色感知功能的程度。