公开(公告)号：US20170145113A1

公开(公告)日：2017-05-25

申请号：US15336171

申请日：2016-10-27

Applicant: Genentech, Inc.

Inventor： Robert F. KELLEY ,  Daniel K. KIRCHHOFER ,  Joyce LAI ,  Chingwei V. LEE ,  Wei-Ching LIANG ,  Michael T. LIPARI ,  Kelly M. LOYET ,  Tao SAI ,  Menno VAN LOOKEREN CAMPAGNE ,  Yan WU ,  Germaine FUH

IPC: C07K16/40

Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.

公开(公告)号：US20150203581A1

公开(公告)日：2015-07-23

申请号：US14593950

申请日：2015-01-09

Applicant: GENENTECH, INC.

Inventor： Wei-Ching LIANG ,  Gregory D. PLOWMAN ,  Yan WU ,  Weilan YE

IPC: C07K16/28 ,  C07K16/22 ,  A61K47/48

CPC classification number: C07K16/2842 ,  A61K47/6835 ,  A61K2039/505 ,  A61K2039/507 ,  C07K16/22 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/92 ,  Y02A50/386 ,  Y02A50/41 ,  Y02A50/412

Abstract: The present invention provides new anti-α5β1 antibodies, compositions and kits comprising the antibodies, and methods of making and using the antibodies.

Abstract translation: 本发明提供新的抗α5和bgr1抗体，包含抗体的组合物和试剂盒，以及制备和使用抗体的方法。