-
41.
公开(公告)号:US4208526A
公开(公告)日:1980-06-17
申请号:US004797
申请日:1979-01-19
IPC分类号: C07D277/20 , A61K31/427 , A61K31/4453 , A61K31/4523 , A61P1/16 , A61P7/10 , C07D277/34 , C07D277/54 , C07D417/04
CPC分类号: C07D277/34 , C07D277/54
摘要: A new and chemically unique one-pot process for the preparation of thiazolidin-4-one-acetic acid derivatives of the general formula: ##STR1## wherein R.sub.1 is a lower alkyl radical.
摘要翻译: 用于制备通式如下的噻唑烷-4-酮 - 乙酸衍生物的新的和化学上独特的一锅法:其中R1是低级烷基。
-
公开(公告)号:US4205078A
公开(公告)日:1980-05-27
申请号:US922018
申请日:1978-07-05
IPC分类号: C07D207/38 , A61K31/40
CPC分类号: C07D207/38
摘要: The present invention is concerned with new 3-pyrrolin-2-one derivatives which exhibit anti-hypertensive and vasodilatory action and with the preparation thereof.
摘要翻译: 本发明涉及具有抗高血压和血管扩张作用及其制备的新型3-吡咯啉-2-酮衍生物。
-
43.
公开(公告)号:US4087544A
公开(公告)日:1978-05-02
申请号:US791677
申请日:1977-04-28
IPC分类号: C07D205/08 , A61K31/215 , A61K31/195
CPC分类号: C07D205/08
摘要: The present invention is concerned with new cyclic amino acids and with the preparation thereof.
摘要翻译: 本发明涉及新的环状氨基酸及其制备。
-
公开(公告)号:US4024175A
公开(公告)日:1977-05-17
申请号:US645724
申请日:1975-12-31
IPC分类号: A61K31/195 , A61K31/215 , A61K31/245 , A61P25/08 , A61P25/20 , C07C67/00 , C07C227/00 , C07C227/04 , C07C227/18 , C07C229/28 , C07D205/08 , C07C101/04 , C07C101/18
CPC分类号: C07D205/08
摘要: The present invention is concerned with new cyclic amino acids and with the preparation thereof.
摘要翻译: 本发明涉及新的环状氨基酸及其制备。
-
公开(公告)号:US3971814A
公开(公告)日:1976-07-27
申请号:US566469
申请日:1975-04-09
IPC分类号: C07D413/04 , C07D333/64
CPC分类号: C07D413/04
摘要: The present invention relates to novel benzo(b)thiophene derivatives of the general formula: ##SPC1##Wherein Y represents a hydrogen or halogen atom; A represents a hydrogen atom or a phenyl group which may be substituted with a halogen atom or a lower alkoxy group; B represents a radical of the formula OR' or NR.sup.2 R.sup.3, wherein R' is an alkyl radical of 1 to 5 carbons which may be substituted with hydroxy, lower alkoxy, phenyl or phenoxy groups or a cycloalkyl or phenyl group which may be substituted by lower alkoxy or halogen atoms; R.sup.2 and R.sup.3, which may be identical or different, represent, if identical, hydrogen, alkyl radicals of 1 to 5 carbon atoms which may be substituted by hydroxy, lower alkoxy, phenoxy, di-lower alkylamino, or phenyl groups; or, if R.sup.2 is hydrogen, R.sup.3 represents either a hydroxyl or an amino group which may be substituted by lower alkyl, dialkyl, alkylidene, phenyl of acyl groups or a lower alkyl group which may be substituted by hydroxy, lower alkoxy, phenoxy, dialkylamino, pyrrolidino, piperidino or morpholino groups; R.sup.3 further is a cycloalkyl or phenyl group, which may be substituted by a halogen or a lower alkoxy radical; or R.sup.2 and R.sup.3 together with the nitrogen atom to which they are attached, may form an aziridine, pyrrolidine, piperidine, morpholine or piperazine ring which may be substituted by lower alkyl, hydroxyalkyl, phenylalkyl, phenyl or acetyl groups; or A and B together with the C=N group may form a 5, 6, or 7-membered heterocyclic ring.
摘要翻译: 本发明涉及以下通式的新型苯并(b)噻吩衍生物:
-
公开(公告)号:US3966779A
公开(公告)日:1976-06-29
申请号:US528125
申请日:1974-11-29
CPC分类号: C07C69/24
摘要: The present invention relates to new thymol derivatives with strong sympatholytic effect and low toxicity and to a process for their preparation.These novel thymol derivatives have the following general formula: ##SPC1##Wherein R is an alkyl group of 4 to 11 carbon atoms or an alkoxy group R'--O-- wherein R' is an alkyl group of 3 to 10 carbon atoms, and their pharmaceutically acceptable salts.
摘要翻译: 本发明涉及具有强交感溶解作用和低毒性的新型百里酚衍生物及其制备方法。
-
公开(公告)号:US3953464A
公开(公告)日:1976-04-27
申请号:US495985
申请日:1974-08-09
申请人: Peter Stoss , Gerhard Satzinger , Manfred Herrmann
发明人: Peter Stoss , Gerhard Satzinger , Manfred Herrmann
IPC分类号: C07D275/06 , C07D275/04
CPC分类号: C07D275/06
摘要: The present invention is concerned with new cyclic sulphoximide derivatives with valuable pharmacological properties and with the preparation thereof.
摘要翻译: 本发明涉及具有有价值的药理学性质的新型环状磺酰亚胺衍生物及其制备方法。
-
公开(公告)号:US3936438A
公开(公告)日:1976-02-03
申请号:US509752
申请日:1974-09-27
申请人: Hartenstein , Gerhard Satzinger , Manfred Herrmann
发明人: Hartenstein , Gerhard Satzinger , Manfred Herrmann
IPC分类号: A61K20060101 , A61K31/56 , A61K31/58 , A61K31/585 , C07C20060101 , C07C71/00 , C07J7/00 , C07J17/00 , C07J19/00 , C07J21/00 , C07J71/00
CPC分类号: C07J19/00
摘要: The present invention is concerned with new cardenolide acetals of the general formula: ##SPC1##Wherein R.sub.1 is an unsubstituted or substituted glycosyl radical and Ar is an unsubstituted or substituted aryl or heteroaryl radical and with the preparation thereof. These compounds exert a positive inotropic action on the cardiac muscle of mammals.
摘要翻译: 本发明涉及新型的具有以下通式的聚烯醇缩醛:
-
公开(公告)号:US5382172A
公开(公告)日:1995-01-17
申请号:US92271
申请日:1993-07-15
申请人: Jurgen Klier , Gerhard Satzinger , Gerhard Schule
发明人: Jurgen Klier , Gerhard Satzinger , Gerhard Schule
IPC分类号: B60R16/02 , B60R16/027 , H01R13/58 , H01R35/02 , H01R39/02
CPC分类号: B60R16/027 , H01R13/5812 , H01R35/025
摘要: A spiral cable which comprises a lower (inner) box part and an upper (outer) box part to wind up a cable spiral and install it at an intended assembly site, for instance at the steering wheel of an automobile. In an outer cylinder wall and an inner cylinder wall the spiral cable box is provided with cable entry openings which allow the cable spiral to be wound up in the box and which allow for the formation of angular end areas which are aligned in parallel to the box to subsequently make an electrical connection.
摘要翻译: 一种螺旋电缆,其包括下部(内部)盒部分和上部(外部)盒部分,以卷起电缆螺旋并将其安装在例如汽车的方向盘的预期组装位置。 在外筒壁和内筒壁中,螺旋电缆箱设有电缆入口,其允许电缆螺旋卷绕在盒中,并且允许形成平行于盒的角度端部区域 随后进行电气连接。
-
公开(公告)号:US4309542A
公开(公告)日:1982-01-05
申请号:US971143
申请日:1978-12-19
IPC分类号: C07D221/18 , A61K31/40 , A61K31/473 , A61K31/485 , A61K31/495 , A61K31/505 , A61K31/54 , A61K31/585 , A61K31/635
CPC分类号: A61K31/54 , A61K31/40 , A61K31/495 , A61K31/505 , A61K31/585 , A61K31/635
摘要: A process for the O-methylation of hydroxyaporphines is disclosed. This process utilizes a trimethylphenylammonium base as the alkylating agent.
摘要翻译: 公开了一种羟基蒽的O-甲基化方法。 该方法利用三甲基苯基铵碱作烷基化剂。
-
-
-
-
-
-
-
-
-