公开(公告)号：US10813564B2

公开(公告)日：2020-10-27

申请号：US14938333

申请日：2015-11-11

Applicant: Hyperfine Research, Inc.

Inventor： Matthew Scot Rosen ,  Gregory L. Charvat ,  Laura Sacolick ,  Mathieu Sarracanie ,  Jonathan M. Rothberg ,  Tyler S. Ralston

IPC: A61B5/04 ,  A61B5/0476 ,  A61B5/00 ,  A61B5/055 ,  G01R33/38 ,  G01R33/381 ,  A61B5/0488 ,  A61B5/0496 ,  A61B5/0402 ,  G01R33/48 ,  G01R33/44 ,  A61B90/00

Abstract: According to some aspects a system is provided comprising a low-field magnetic resonance (MR) device, at least one electrophysiological device, and at least one controller configured to operate the low-field MR device to obtain MR data and to operate the at least one electrophysiological device to obtain electrophysiological data.

公开(公告)号：US20200249297A1

公开(公告)日：2020-08-06

申请号：US16806532

申请日：2020-03-02

Applicant: Hyperfine Research, Inc.

Inventor： Laura Sacolick ,  Matthew Scot Rosen ,  Gregory L. Charvat ,  Jonathan M. Rothberg ,  Mathieu Sarracanie

IPC: G01R33/44 ,  G01R33/561 ,  G01R33/48

Abstract: A low-field magnetic resonance imaging (MRI) system. The system includes a plurality of magnetics components comprising at least one first magnetics component configured to produce a low-field main magnetic field B0 and at least one second magnetics component configured to acquire magnetic resonance data when operated, and at least one controller configured to operate one or more of the plurality of magnetics components in accordance with at least one low-field zero echo time (LF-ZTE) pulse sequence.

公开(公告)号：US10718842B2

公开(公告)日：2020-07-21

申请号：US15820182

申请日：2017-11-21

Applicant: Hyperfine Research, Inc.

Inventor： Michal Sofka ,  Jonathan M. Rothberg ,  Gregory L. Charvat ,  Tyler S. Ralston

IPC: G01R33/00 ,  G01R33/56 ,  G01R33/38 ,  G06K9/62 ,  A61B5/00 ,  A61B5/055 ,  G01R33/44 ,  G01R33/483 ,  G06T7/00 ,  G01R33/48 ,  G01R33/383 ,  G06N3/04

Abstract: Some aspects include a method of determining change in size of an abnormality in a brain of a patient positioned within a low-field magnetic resonance imaging (MRI) device. The method comprises, while the patient remains positioned within the low-field MRI device, acquiring first and second magnetic resonance (MR) image data of the patient's brain; providing the first and second MR image data as input to a trained statistical classifier to obtain corresponding first and second output; identifying, using the first output, at least one initial value of at least one feature indicative of a size of the abnormality; identifying, using the second output, at least one updated value of the at least one feature; determining the change in the size of the abnormality using the at least one initial value of the at least one feature and the at least one updated value of the at least one feature.

公开(公告)号：US10684335B2

公开(公告)日：2020-06-16

申请号：US16275285

申请日：2019-02-13

Applicant: Hyperfine Research, Inc.

Inventor： Michael Stephen Poole ,  Cedric Hugon ,  Hadrien A. Dyvorne ,  Laura Sacolick ,  William J. Mileski ,  Jeremy Christopher Jordan ,  Alan B. Katze, Jr. ,  Jonathan M. Rothberg ,  Todd Rearick ,  Christopher Thomas McNulty

IPC: G01R33/385 ,  G01R33/383 ,  G01R33/44 ,  A61B50/13 ,  G01R33/389 ,  G01R33/421 ,  G01R33/56 ,  G01R33/38 ,  A61B5/055 ,  A61B6/00 ,  A61G13/10 ,  G01R33/34 ,  G01R33/48 ,  A61B90/00 ,  G01R33/3873 ,  G01R33/36 ,  G01R33/422

Abstract: According to some aspects, a portable magnetic resonance imaging system is provided, comprising a B0 magnet configured to produce a B0 magnetic field for an imaging region of the magnetic resonance imaging system, a noise reduction system configured to detect and suppress at least some electromagnetic noise in an operating environment of the portable magnetic resonance imaging system, and electromagnetic shielding provided to attenuate at least some of the electromagnetic noise in the operating environment of the portable magnetic resonance imaging system, the electromagnetic shielding arranged to shield a fraction of the imaging region of the portable magnetic resonance imaging system. According to some aspects, the electromagnetic shield comprises at least one electromagnetic shield structure adjustably coupled to the housing to provide electromagnetic shielding for the imaging region in an amount that can be varied. According to some aspects, substantially no shielding of the imaging region of the portable magnetic resonance imaging system is provided.

公开(公告)号：US10649050B2

公开(公告)日：2020-05-12

申请号：US16667813

申请日：2019-10-29

Applicant: Hyperfine Research, Inc.

Inventor： Michael Stephen Poole ,  Cedric Hugon ,  Hadrien A. Dyvorne ,  Laura Sacolick ,  William J. Mileski ,  Jeremy Christopher Jordan ,  Alan B. Katze, Jr. ,  Jonathan M. Rothberg ,  Todd Rearick ,  Christopher Thomas McNulty

IPC: G01R33/48 ,  G01R33/385 ,  G01R33/34 ,  A61G13/10 ,  A61B6/00 ,  A61B5/055 ,  G01R33/38 ,  G01R33/56 ,  G01R33/421 ,  G01R33/389 ,  A61B50/13 ,  G01R33/44 ,  G01R33/383 ,  A61B90/00 ,  G01R33/422 ,  G01R33/36 ,  G01R33/3873

Abstract: According to some aspects, a low-field magnetic resonance imaging system is provided. The low-field magnetic resonance imaging system comprises a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, the magnetics system comprising, a B0 magnet configured to produce a B0 field for the magnetic resonance imaging system at a low-field strength of less than 0.2 Tesla (T), a plurality of gradient coils configured to, when operated, generate magnetic fields to provide spatial encoding of magnetic resonance signals, and at least one radio frequency coil configured to, when operated, transmit radio frequency signals to a field of view of the magnetic resonance imaging system and to respond to magnetic resonance signals emitted from the field of view, a power system comprising one or more power components configured to provide power to the magnetics system to operate the magnetic resonance imaging system to perform image acquisition, and a power connection configured to connect to a single-phase outlet to receive mains electricity and deliver the mains electricity to the power system to provide power needed to operate the magnetic resonance imaging system. According to some aspects, the power system operates the low-field magnetic resonance imaging system using an average of less than 1.6 kilowatts during image acquisition.

公开(公告)号：US20200064427A1

公开(公告)日：2020-02-27

申请号：US16667813

申请日：2019-10-29

Applicant: Hyperfine Research, Inc.

Inventor： Michael Stephen Poole ,  Cedric Hugon ,  Hadrien A. Dyvorne ,  Laura Sacolick ,  William J. Mileski ,  Jeremy Christopher Jordan ,  Alan B. Katze, JR. ,  Jonathan M. Rothberg ,  Todd Rearick ,  Christopher Thomas McNulty

IPC: G01R33/385 ,  A61B90/00 ,  G01R33/48 ,  G01R33/34 ,  A61G13/10 ,  A61B6/00 ,  A61B5/055 ,  G01R33/38 ,  G01R33/56 ,  G01R33/421 ,  G01R33/389 ,  A61B50/13 ,  G01R33/44 ,  G01R33/383

Abstract: According to some aspects, a low-field magnetic resonance imaging system is provided. The low-field magnetic resonance imaging system comprises a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, the magnetics system comprising, a B0 magnet configured to produce a B0 field for the magnetic resonance imaging system at a low-field strength of less than 0.2 Tesla (T), a plurality of gradient coils configured to, when operated, generate magnetic fields to provide spatial encoding of magnetic resonance signals, and at least one radio frequency coil configured to, when operated, transmit radio frequency signals to a field of view of the magnetic resonance imaging system and to respond to magnetic resonance signals emitted from the field of view, a power system comprising one or more power components configured to provide power to the magnetics system to operate the magnetic resonance imaging system to perform image acquisition, and a power connection configured to connect to a single-phase outlet to receive mains electricity and deliver the mains electricity to the power system to provide power needed to operate the magnetic resonance imaging system. According to some aspects, the power system operates the low-field magnetic resonance imaging system using an average of less than 1.6 kilowatts during image acquisition.

公开(公告)号：US10416264B2

公开(公告)日：2019-09-17

申请号：US15820073

申请日：2017-11-21

Applicant: Hyperfine Research, Inc.

Inventor： Michal Sofka ,  Jonathan M. Rothberg ,  Gregory L. Charvat ,  Tyler S. Ralston

IPC: G01R33/56 ,  G01R33/44 ,  G01R33/483 ,  G06T7/00 ,  G06K9/62 ,  A61B5/00 ,  A61B5/055 ,  G01R33/48 ,  G01R33/38 ,  G01R33/383 ,  G06N3/04

Abstract: Some aspects include a method of detecting change in degree of midline shift in a brain of a patient. The method comprises, while the patient remains positioned within the low-field magnetic resonance imaging device, acquiring first magnetic resonance (MR) image data and second MR image data of the patient's brain; providing the first and second MR data as input to a trained statistical classifier to obtain corresponding first and second output, identifying, from the first output, at least one initial location of at least one landmark associated with at least one midline structure of the patient's brain; identifying, from the second output, at least one updated location of the at least one landmark; and determining a degree of change in the midline shift using the at least one initial location of the at least one landmark and the at least one updated location of the at least one landmark.

公开(公告)号：US20190086497A1

公开(公告)日：2019-03-21

申请号：US16195518

申请日：2018-11-19

Applicant: Hyperfine Research, Inc.

Inventor： Todd Rearick ,  Gregory L. Charvat ,  Matthew Scot Rosen ,  Jonathan M. Rothberg

IPC: G01R33/56 ,  G01R33/36 ,  G01R33/565 ,  G01R33/385 ,  G01R33/58 ,  G01R33/48 ,  H01F7/02 ,  H01F7/06 ,  G01R33/383 ,  G01R33/54 ,  G01R33/38 ,  G01R33/44 ,  G01R33/381 ,  G01R33/3875 ,  G01R33/34 ,  G01R33/28 ,  G01R33/422

Abstract: According to some aspects, a method of suppressing noise in an environment of a magnetic resonance imaging system is provided. The method comprising estimating a transfer function based on multiple calibration measurements obtained from the environment by at least one primary coil and at least one auxiliary sensor, respectively, estimating noise present in a magnetic resonance signal received by the at least one primary coil based at least in part on the transfer function, and suppressing noise in the magnetic resonance signal using the noise estimate.

公开(公告)号：US10222435B2

公开(公告)日：2019-03-05

申请号：US16123941

申请日：2018-09-06

Applicant: Hyperfine Research, Inc.

Inventor： William J. Mileski ,  Gregory L. Charvat ,  Jonathan M. Rothberg ,  Jeremy Christopher Jordan

IPC: G01R33/00 ,  G01R33/385 ,  G05F1/46 ,  G01R33/46 ,  G01R33/38

Abstract: An apparatus to provide power for operating at least one gradient coil of a magnetic resonance imaging system. According to some aspects, the apparatus comprises a plurality of power terminals configured to supply different voltages of a first polarity, and a linear amplifier configured to provide at least one output to power the at least one gradient coil to produce a magnetic field in accordance with a pulse sequence, the linear amplifier configured to be powered by one or more of the plurality of power terminals, wherein the one or more of the plurality of power terminals powering the linear amplifier is selected based, at least in part, on the at least one output.

公开(公告)号：US20190004130A1

公开(公告)日：2019-01-03

申请号：US16122661

申请日：2018-09-05

Applicant: Hyperfine Research, Inc.

Inventor： Michael Stephen Poole ,  Cedric Hugon ,  Hadrien A. Dyvorne ,  Laura Sacolick ,  William J. Mileski ,  Jeremy Christopher Jordan ,  Alan B. Katze, JR. ,  Jonathan M. Rothberg ,  Todd Rearick ,  Christopher Thomas McNulty

IPC: G01R33/385 ,  G01R33/383 ,  G01R33/389 ,  A61B50/13 ,  A61B90/00

Abstract: According to some aspects, a portable magnetic resonance imaging system is provided, comprising a B0 magnet configured to produce a B0 magnetic field for an imaging region of the magnetic resonance imaging system, a noise reduction system configured to detect and suppress at least some electromagnetic noise in an operating environment of the portable magnetic resonance imaging system, and electromagnetic shielding provided to attenuate at least some of the electromagnetic noise in the operating environment of the portable magnetic resonance imaging system, the electromagnetic shielding arranged to shield a fraction of the imaging region of the portable magnetic resonance imaging system. According to some aspects, the electromagnetic shield comprises at least one electromagnetic shield structure adjustably coupled to the housing to provide electromagnetic shielding for the imaging region in an amount that can be varied.