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52 条记录 (耗时 0.062 秒)

    Tissue adhesive with accelerated curing
    43.
    发明授权
    Tissue adhesive with accelerated curing 有权
    组织粘合剂加速固化

    公开(公告)号：US09254347B2

    公开(公告)日：2016-02-09

    申请号：US14112132

    申请日：2012-04-17

    申请人： Heike Heckroth ,  Christoph Eggert

    发明人： Heike Heckroth ,  Christoph Eggert

    IPC分类号： C08G18/32 ,  C08G18/38 ,  C08G18/10 ,  A61L24/04 ,  A61B17/03 ,  C09J175/02 ,  A61M5/19 ,  C08G18/12 ,  C08G18/73 ,  A61L24/00 ,  A61B17/00

    CPC分类号： A61L24/046 ,  A61B17/00491 ,  A61B2017/00495 ,  A61L24/0015 ,  A61M5/19 ,  C08G18/10 ,  C08G18/12 ,  C08G18/325 ,  C08G18/3821 ,  C08G18/73 ,  C09J175/02 ,  C08L75/02

    摘要： The present invention relates to a polyurea system encompassing as component A) isocyanate-functional prepolymers obtainable by reaction of aliphatic isocyanates A1) with polyols A2), which can in particular have a number average molecular weight of ≧400 g/mol and an average OH functionality of 2 to 6, as component B) amino-functional compounds of general formula (I) in which X is an organic residue comprising a tertiary amino function, having no Zerewitinoff active hydrogen, R1 is a CH2—COOR3 residue, in which R3 is an organic residue having no Zerewitinoff active hydrogen, a linear or branched C1 to C4 alkyl residue, a cyclopentyl or cyclohexyl residue or H, R2 is an organic residue having no Zerewitinoff active hydrogen, n is an integer ≧2 or ≦3, in particular for closing, binding, bonding or covering cell tissue, and to a metering system for the polyurea system according to the invention.

    摘要翻译： 本发明涉及一种包含作为组分A）的异氰酸酯官能预聚物，该聚脲体系可通过脂族异氰酸酯A1）与多元醇A2）的反应获得，该多异氰酸酯官能的预聚物特别是数均分子量≥400g/ mol，平均OH 2至6的官能团，作为组分B）通式（I）的氨基官能化合物，其中X是包含叔氨基官能团的有机残基，不具有泽瑞维诺夫活性氢，R 1是CH 2 -COOR 3残基，其中R 3 是不具有齐维诺夫活性氢的有机残基，直链或支链C 1至C 4烷基残基，环戊基或环己基残基或H，R 2是不具有齐维诺夫活性氢的有机残基，n为整数≥2或nlE; 3， 特别是用于封闭，结合，粘合或覆盖细胞组织，以及用于根据本发明的聚脲系统的计量系统。

    TISSUE ADHESIVE BASED ON NITROGEN-MODIFIED ASPARTATES
    44.
    发明申请
    TISSUE ADHESIVE BASED ON NITROGEN-MODIFIED ASPARTATES 有权
    基于硝酸改性乳膏的组织粘合剂

    公开(公告)号：US20130325062A1

    公开(公告)日：2013-12-05

    申请号：US13984186

    申请日：2012-02-06

    申请人： Heike Heckroth ,  Christoph Eggert

    发明人： Heike Heckroth ,  Christoph Eggert

    IPC分类号： A61L24/04 ,  A61L24/00

    CPC分类号： A61L24/046 ,  A61L24/0015 ,  C08G18/10 ,  C08G18/3821 ,  C08G18/4252 ,  C08G18/73 ,  C08L75/04

    摘要： The invention relates to a polyurea system comprising as component A) isocyanate-functional prepolymers which can be obtained by reacting aliphatic isocyanates A1) with polyols A2) that can have a number-average molecular weight of =400 g/mol and an average OH functionality of 2 to 6 in particular; and as component B) amino-functional aspartic acid esters of the general formula (I) in which X is an organic group containing a secondary amino function, R1, R2 are the same or different organic groups that do not have Zerewitinoff-active hydrogen, and n is a whole number of at least 2, in particular for sealing, bonding, gluing, or covering cell tissue. The invention also relates to a metering system for the polyurea system according to the invention.

    摘要翻译： 本发明涉及一种包含作为组分A）异氰酸酯官能的预聚物的聚脲体系，该异氰酸酯官能的预聚物可通过使脂族异氰酸酯A1）与数均分子量为400g / mol和平均OH官能度的多元醇A2） 特别是2到6; 和作为组分B）通式（I）的氨基官能天冬氨酸酯，其中X是含有仲氨基官能团的有机基团，R 1，R 2是相同或不同的不具有齐维诺芬活性氢的有机基团， 并且n是至少为2的整数，特别是用于密封，粘合，胶合或覆盖细胞组织。 本发明还涉及根据本发明的聚脲系统的计量系统。

    ELECTROMECHANICAL TRANSDUCER HAVING A POLYISOCYANATE-BASED POLYMER ELEMENT
    46.
    发明申请
    ELECTROMECHANICAL TRANSDUCER HAVING A POLYISOCYANATE-BASED POLYMER ELEMENT 审中-公开
    具有聚异氰酸酯基聚合物元件的机电传感器

    公开(公告)号：US20110298335A1

    公开(公告)日：2011-12-08

    申请号：US13056178

    申请日：2009-07-17

    申请人： Werner Jenninger ,  Sebastian Dörr ,  Joachim Wagner ,  Burkhard Köhler ,  Heike Heckroth ,  Mathias Matner

    发明人： Werner Jenninger ,  Sebastian Dörr ,  Joachim Wagner ,  Burkhard Köhler ,  Heike Heckroth ,  Mathias Matner

    IPC分类号： H01L41/193 ,  H02N2/18 ,  H01L41/04

    CPC分类号： H01L41/45 ,  C08G18/10 ,  C08G18/3225 ,  C08G18/3821 ,  C09D175/02 ,  H01L41/193

    摘要： The present invention relates to an electromechanical transducer, in particular an electromechanical sensor, actuator and/or generator, which exhibits a polymer element that is obtainable from a reaction mixture comprising a polyisocyanate or a polyisocyanate prepolymer or a mixture thereof and a compound with at least two isocyanate-reactive amino groups. Moreover, the present invention relates to a process for producing an electromechanical transducer of such a type and also to the use of a polymer element of such a type as an electromechanical element. Furthermore, the present invention relates to an electronic and/or electrical apparatus that includes an electromechanical transducer according to the invention, and also to the use of an electromechanical transducer according to the invention in an electronic and/or electrical apparatus.

    摘要翻译： 本发明涉及机电换能器，特别是机电传感器，致动器和/或发电机，其表现出聚合物元件，该聚合物元件可从包含多异氰酸酯或多异氰酸酯预聚物或其混合物的反应混合物获得，并且至少具有化合物 两个异氰酸酯反应性氨基。 此外，本发明涉及一种用于制造这种类型的机电换能器的方法，并且还涉及使用这种类型的机电元件的聚合物元件。 此外，本发明涉及包括根据本发明的机电换能器的电子和/或电气设备，并且还涉及在电子和/或电气设备中使用根据本发明的机电换能器。

    Polyurea Systems, Processes for Preparing the Same and Use Thereof for Postoperative Adhesion Barriers
    48.
    发明申请
    Polyurea Systems, Processes for Preparing the Same and Use Thereof for Postoperative Adhesion Barriers 有权
    聚脲系统，其制备方法及其应用于术后粘合屏障

    公开(公告)号：US20090221071A1

    公开(公告)日：2009-09-03

    申请号：US12370639

    申请日：2009-02-13

    申请人： Heike Heckroth ,  Hartmut Nefzger ,  Christian Wamprecht

    发明人： Heike Heckroth ,  Hartmut Nefzger ,  Christian Wamprecht

    IPC分类号： C12N5/06 ,  C08G18/00 ,  C08L75/04 ,  C08K5/053

    CPC分类号： C08G18/3821 ,  A61L15/26 ,  A61L31/06 ,  A61L31/148 ,  A61L2430/00 ,  C08G18/10 ,  C08G18/4252 ,  C08G18/4841 ,  C08G18/485 ,  C08G18/73 ,  C08G18/7621 ,  Y10T428/31551 ,  Y10T428/31594 ,  C08L75/02

    摘要： Polyurea systems comprising: (a) an amino-functional aspartic ester of the general formula (I) wherein X represents an n-valent organic radical derived from a corresponding n-functional primary amine X(NH2)n, R1 and R2 each independently represent an organic radical having no Zerevitinov active hydrogens and n represents an integer of at least 2; and (b) an isocyanate functional prepolymer having a residual monomer content of less than 1% by weight, the prepolymer prepared by reacting: (b1) an aliphatic isocyante; and (b2) a polyol component having a number average molecular weight of ≧400 g/mol and an average OH functionality of 2 to 6, wherein the polyol component comprises one or more constituents selected from the group consisting of polyester polyols, polyester-polyether polyols and mixtures thereof; processes for making the same; postoperative adhesions barriers prepared therewith and dispensing systems for such polyurea systems.

    摘要翻译： 聚脲体系包括：（a）通式（I）的氨基官能天冬氨酸酯，其中X表示衍生自相应的正官能伯胺X（NH 2）n的n价有机基团，R 1和R 2各自独立地表示 没有泽列维诺夫活性氢的有机基团，n表示至少2的整数; 和（b）具有小于1重量％的残余单体含量的异氰酸酯官能预聚物，所述预聚物通过使（b1）脂族异氰酸酯反应制备; 和（b2）数均分子量> = 400g / mol，平均OH官能度为2-6的多元醇组分，其中多元醇组分包括一种或多种选自聚酯多元醇，聚酯 - 聚醚多元醇及其混合物; 制作相同的过程; 用其制备的术后粘连屏障和用于这种聚脲系统的分配系统。

    ADHESIVE SYSTEMS CONTAINING POLYISOCYANATE PREPOLYMERS AND ASPARTATE-ESTER CURING AGENTS, PROCESSES FOR PREPARING THE SAME, MEDICAL USES THEREFOR AND DISPENSING SYSTEMS FOR THE SAME
    50.
    发明申请
    ADHESIVE SYSTEMS CONTAINING POLYISOCYANATE PREPOLYMERS AND ASPARTATE-ESTER CURING AGENTS, PROCESSES FOR PREPARING THE SAME, MEDICAL USES THEREFOR AND DISPENSING SYSTEMS FOR THE SAME 审中-公开
    含有聚异氰酸酯预处理剂和乳酸酯固化剂的粘合剂体系，其制备方法，用于其的医疗用途和分配体系

    公开(公告)号：US20090191145A1

    公开(公告)日：2009-07-30

    申请号：US12358346

    申请日：2009-01-23

    申请人： Heike Heckroth ,  Burkhardt Kohler ,  Sebastian Dorr

    发明人： Heike Heckroth ,  Burkhardt Kohler ,  Sebastian Dorr

    IPC分类号： A61K31/785 ,  C09J175/00

    CPC分类号： C08G18/4837 ,  A61L24/046 ,  C08G18/10 ,  C08G18/73 ,  C09J175/04 ,  C08G18/3821 ,  C08G18/48 ,  C08G18/6685

    摘要： Adhesive systems comprising: (A) an isocyanate group-containing prepolymer prepared by reacting: (A1) an aliphatic isocyante; and (A2) a polyol having a number average molecular weight of ≧400 g/mol and 2 to 6 OH groups; and (B) a curing component comprising: (B1) an amino group-containing aspartate ester of the general formula (I); wherein X represents an n-valent organic radical derived from a corresponding n-functional primary amine X(NH2)n, R1 and R2 each independently represent an organic radical having no Zerevitinov active hydrogens and n represents a whole number of at least 2; and (B2) an organic filler having a viscosity of 10 to 6000 mPas at 23° C. measured according to DIN 53019; their use in wound and tissue incision closure, adhesive films comprising the same and dispensing systems therefor.

    摘要翻译： 粘合剂体系包括：（A）含异氰酸酯基的预聚物，其通过使（A1）脂族异氰酸酯反应而制备; 和（A2）数均分子量为> 400g / mol和2-6个OH基的多元醇; 和（B）固化组分，其包含：（B1）通式（I）的含氨基的天冬氨酸酯; 其中X表示衍生自相应的正官能伯胺X（NH 2）n的n价有机基团，R 1和R 2各自独立地表示不具有齐维可诺夫活性氢的有机基团，n表示整数至少为2; 和（B2）根据DIN 53019测量的在23℃下粘度为10至6000mPa·s的有机填料; 它们在伤口和组织切口闭合中的应用，包括其的粘合剂膜和其分配系统。