公开(公告)号：US20080085904A1

公开(公告)日：2008-04-10

申请号：US11659967

申请日：2005-07-14

Applicant: Hans-Michael Eggenweiler ,  Michael Wolf

Inventor： Hans-Michael Eggenweiler ,  Michael Wolf

IPC: A61K31/415 ,  A61K31/4439 ,  A61K31/454 ,  A61K31/496 ,  A61P31/12 ,  A61P35/00 ,  C07D231/12 ,  C07D401/02 ,  C07D403/02

CPC classification number: C07D231/12 ,  C07D405/04

Abstract: Novel 1,5 diphenylpyrazole derivatives of the formula (I), in which R1-R6 have the meanings indicated in Claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 plays a role.

Abstract translation: 具有权利要求1所述含义的式（I）的新型1,5二苯基吡唑衍生物，其中R 1〜R 6具有HSP90抑制剂，可用于 制备用于治疗HSP90的抑制，调节和/或调节发挥作用的疾病的药物。

公开(公告)号：US20080006573A1

公开(公告)日：2008-01-10

申请号：US11822559

申请日：2007-07-06

Applicant: Michael Wolf ,  Jukka Schaerlund

Inventor： Michael Wolf ,  Jukka Schaerlund

IPC: B01D35/28

CPC classification number: B01D27/08 ,  B01D2201/34

Abstract: An exchangeable filter (10), e.g. for filtering lubricating oil in internal combustion engines, having a housing (11) including a vessel (12), a lid (13) and a seal (25). A filter element (21) is situated inside the housing (11) in such a way that an oil inlet (18) is sealingly separated from an oil outlet (19). The lid (13) has a seal holder (15), in which a groove (27) for receiving the seal (25) is arranged. The seal (25) preferably has a beveled area (26), which projects at least partially beyond the seal holder (15). As a result of this beveled area (26), only small mounting forces are required to mount the exchangeable filter (10).

Abstract translation: 可更换过滤器（10） 用于过滤内燃机中的润滑油，具有包括容器（12），盖（13）和密封件（25）的壳体（11）。 过滤元件（21）位于壳体（11）的内部，使得油入口（18）与油出口（19）密封地分离。 盖（13）具有密封保持器（15），其中布置有用于接收密封件（25）的凹槽（27）。 密封件（25）优选地具有至少部分地超过密封保持器（15）突出的斜面区域（26）。 作为该斜面区域26的结果，仅需要小的安装力来安装可更换的过滤器（10）。

公开(公告)号：US20070294501A1

公开(公告)日：2007-12-20

申请号：US11894434

申请日：2007-08-20

Applicant: Michael Wolf ,  Gil Tene ,  Luca Castellano

Inventor： Michael Wolf ,  Gil Tene ,  Luca Castellano

IPC: G06F12/00

CPC classification number: G06F12/023 ,  G06F9/5016 ,  G06F9/5022 ,  G06F2209/5011 ,  Y10S707/99953 ,  Y10S707/99956

Abstract: A computer system includes a memory and a processor coupled with the memory, configured to assign to each of a plurality of processes a corresponding amount of committed memory from a memory pool, the memory pool including committed memory and uncommitted memory; and dynamically allocate an additional amount of memory required by one of the plurality of processes from the uncommitted memory in the memory pool. Managing memory includes assigning to each of a plurality of processes a corresponding amount of committed memory from a memory pool, the memory pool including committed memory and uncommitted memory; and dynamically allocating an additional amount of memory required by one of the plurality of processes from the uncommitted memory in the memory pool.

Abstract translation: 计算机系统包括存储器和与存储器耦合的处理器，被配置为向存储器池分配相应量的已提交存储器，所述存储器池包括提交的存储器和未提交的存储器; 并且从所述存储器池中的未提交的存储器动态地分配所述多个进程之一所需的附加量的存储器。 管理存储器包括向存储器池分配相应量的已提交存储器，所述存储器池包括已提交的存储器和未提交的存储器; 以及从所述存储器池中的未提交的存储器动态地分配所述多个进程之一所需的附加量的存储器。

公开(公告)号：USD545033S1

公开(公告)日：2007-06-26

申请号：US29254055

申请日：2006-02-16

Applicant: Michael Wolf

Designer： Michael Wolf

公开(公告)号：USD545032S1

公开(公告)日：2007-06-26

申请号：US29253114

申请日：2006-02-01

Applicant: Michael Wolf

Designer： Michael Wolf

公开(公告)号：US20060270676A1

公开(公告)日：2006-11-30

申请号：US11497235

申请日：2006-08-02

Applicant: Hans-Michael Eggenweiler ,  Michael Wolf ,  Norbert Beier ,  Pierre Schelling ,  Thomas Ehring

Inventor： Hans-Michael Eggenweiler ,  Michael Wolf ,  Norbert Beier ,  Pierre Schelling ,  Thomas Ehring

IPC: A61K31/501 ,  A61K31/50 ,  C07D403/02

CPC classification number: C07D403/12 ,  C07D237/04

Abstract: Hydrazono-malonitrile derivatives of the formula (I) in which R1, R2, R3, R3′ and R4 have the meanings given in Claim 1 act as phosphodiesterase IV inhibitors and can be employed for the treatment of osteoporosis, tumours, cachexia, atherosclerosis, rheumatoid arthritis, multiple sclerosis, diabetes mellitus, inflammatory processes, allergies, asthma, autoimmune diseases, myocardial diseases and AIDS.

Abstract translation: 式（I）的肼 - 丙腈衍生物其中R 1，R 2，R 3，R 3， SUP>和R 4具有权利要求1中给出的含义作为磷酸二酯酶IV抑制剂，并且可用于治疗骨质疏松症，肿瘤，恶病质，动脉粥样硬化，类风湿性关节炎，多发性硬化，糖尿病，炎性 过程，过敏，哮喘，自身免疫性疾病，心肌疾病和艾滋病。

公开(公告)号：US07135471B2

公开(公告)日：2006-11-14

申请号：US10517438

申请日：2003-05-16

Applicant: Hans-Michael Eggenweiler ,  Norbert Beier ,  Pierre Schelling ,  Michael Wolf

Inventor： Hans-Michael Eggenweiler ,  Norbert Beier ,  Pierre Schelling ,  Michael Wolf

IPC: C07D403/12 ,  C07D237/04 ,  A61K31/501 ,  A61K31/50

CPC classification number: C07D401/12 ,  C07D237/04 ,  C07D403/12

Abstract: Aryl oxime derivatives of the formula (I), in which R1, R2, R3, X and B are as defined in claim 1, act as phosphodiesterase IV inhibitors and can be employed for the treatment of osteoporosis, tumours, cachexia, atherosclerosis, rheumatoid arthritis, multiple sclerosis, diabetes mellitus, inflammatory processes, allergies, asthma, autoimmune diseases, myocardial diseases and AIDS

Abstract translation: 式（I）的芳基肟衍生物，其中R 1，R 2，R 3，X和B如权利要求中所定义， 1，作为磷酸二酯酶IV抑制剂，可用于治疗骨质疏松症，肿瘤，恶病质，动脉粥样硬化，类风湿性关节炎，多发性硬化，糖尿病，炎症过程，过敏，哮喘，自身免疫性疾病，心肌病和艾滋病

公开(公告)号：US07129241B2

公开(公告)日：2006-10-31

申请号：US10516876

申请日：2003-05-12

Applicant: Hans-Michael Eggenweiler ,  Michael Wolf

Inventor： Hans-Michael Eggenweiler ,  Michael Wolf

IPC: C07D403/12 ,  C07D237/04 ,  A61K31/501 ,  A61K31/50 ,  A61P11/06

CPC classification number: C07D401/06 ,  C07D237/04 ,  C07D401/12

Abstract: Pyridazine derivatives of the formula (I) act as phosphodiesterase IV inhibitors and can be employed for the treatment of osteoporosis, tumours, cachexia, atherosclerosis, rheumatoid arthritis, multiple sclerosis, diabetes mellitus, inflammatory processes, allergies, asthma, autoimmune diseases, myocardial diseases and AIDS

Abstract translation: 式（I）的哒嗪衍生物作为磷酸二酯酶IV抑制剂，可用于治疗骨质疏松症，肿瘤，恶病质，动脉粥样硬化，类风湿性关节炎，多发性硬化，糖尿病，炎症过程，过敏，哮喘，自身免疫疾病，心肌疾病 和艾滋病

公开(公告)号：US20060180539A1

公开(公告)日：2006-08-17

申请号：US11354169

申请日：2006-02-15

Applicant: Michael Wolf ,  Joachim Stinzendoerfer ,  Karlheinz Muenkel ,  Ralf Bauder ,  Norbert Maurer

Inventor： Michael Wolf ,  Joachim Stinzendoerfer ,  Karlheinz Muenkel ,  Ralf Bauder ,  Norbert Maurer

IPC: B01D27/08 ,  B01D35/02

CPC classification number: B01D29/055 ,  B01D35/30 ,  B01D2201/0407 ,  B01D2201/4046

Abstract: An oil filter for an internal combustion engine with a cup-shaped housing that is releasably connectable to a receiving head. The housing has a first interlocking element that extends across at least a portion of the outer circumference of the housing and is interrupted by at least one axially extending recess. The filter element has a liquid-tight canister provided on its outer surface with second interlocking elements, which fit into the recesses of corresponding first interlocking elements when the filter element is installed in the housing.

Abstract translation: 一种用于具有可释放地连接到接收头的杯形壳体的内燃机的油过滤器。 壳体具有第一互锁元件，其跨过壳体的外周的至少一部分延伸并且被至少一个轴向延伸的凹部中断。 过滤元件具有在其外表面上设置有第二互锁元件的液密罐，当过滤元件安装在壳体中时，第二互锁元件装配在相应的第一互锁元件的凹部中。

公开(公告)号：US20050061991A1

公开(公告)日：2005-03-24

申请号：US10949595

申请日：2004-09-24

Applicant: James Griggs ,  David Steklenski ,  Michael Wolf ,  John Attwood

Inventor： James Griggs ,  David Steklenski ,  Michael Wolf ,  John Attwood

IPC: G01T1/04

CPC classification number: G01T1/04 ,  G01T1/02

Abstract: A dosimeter and method of measuring an absorbed dose of ionizing radiation using the dosimeter comprising at least one first region containing a radiation sensitive material, and a second region containing an identification mark are described, wherein the method includes the steps of: providing a first region including a radiation sensitive material capable of measuring an absorbed dose of ionizing radiation; providing a second region bearing an identification mark; exposing at least the first region to a dose of ionizing radiation; and reading the signal from the first region. The dosimeter can be used to track location and irradiation of an associated good.

Abstract translation: 描述了使用包含至少一个包含辐射敏感材料的第一区域和包含识别标记的第二区域的剂量计来测量电离辐射吸收剂量的剂量计和方法，其中所述方法包括以下步骤：提供第一区域 包括能够测量电离辐射吸收剂量的辐射敏感材料; 提供带有识别标记的第二区域; 将至少第一区域暴露于一定剂量的电离辐射; 并读取来自第一区域的信号。 剂量计可用于跟踪相关产品的位置和照射。