MEASURING GLOMERULAR NUMBER FROM KIDNEY MRI IMAGES
    43.
    发明申请
    MEASURING GLOMERULAR NUMBER FROM KIDNEY MRI IMAGES 有权
    从KIDNEY MRI图像中测量GLOMERULAR数

    公开(公告)号:US20160005170A1

    公开(公告)日:2016-01-07

    申请号:US14853645

    申请日:2015-09-14

    IPC分类号: G06T7/00 G06T11/60 G06K9/62

    摘要: Measuring the number of glomeruli in the entire, intact kidney using non-destructive techniques is of immense importance in studying several renal and systemic diseases. In particular, a recent Magnetic Resonance Imaging (MRI) technique, based on injection of a contrast agent, cationic ferritin, has been effective in identifying glomerular regions in the kidney. In various embodiments, a low-complexity, high accuracy method for obtaining the glomerular count from such kidney MRI images is described. This method employs a patch-based approach for identifying a low-dimensional embedding that enables the separation of glomeruli regions from the rest. By using only a few images marked by the expert for learning the model, the method provides an accurate estimate of the glomerular number for any kidney image obtained with the contrast agent. In addition, the implementation of our method shows that this method is near real-time, and can process about 5 images per second.

    摘要翻译: 使用非破坏性技术测量整个完整肾中的肾小球数量对于研究几种肾脏和全身疾病是非常重要的。 特别地,基于注射造影剂阳离子铁蛋白的最近的磁共振成像(MRI)技术已经有效地鉴定了肾脏中的肾小球区域。 在各种实施例中,描述了用于从这样的肾MRI图像获得肾小球计数的低复杂度,高精度方法。 该方法采用基于贴片的方法来识别能够将肾小球区域与其余部分分离的低维度嵌入。 通过仅使用由专家标记的几个图像来学习模型,该方法提供了用造影剂获得的任何肾脏图像的肾小球数的准确估计。 此外,我们的方法的实现表明这种方法接近实时,每秒可以处理大约5张图像。