公开(公告)号：US08125338B2

公开(公告)日：2012-02-28

申请号：US12491215

申请日：2009-06-24

申请人： Lin Li

发明人： Lin Li

IPC分类号： G08B13/14

CPC分类号： G08B13/2408

摘要： An acousto-magnetic (AM) anti-theft alarming unit is designed for specific use in a hard tag anti-theft clamp which uses a magnetic detacher. The alarming unit includes a resonator housing defining a cavity in which is placed at least one resonator and a bias piece covered by a housing cover affixed to the resonator housing. The resonators are placed into the housing cavity in a vertically layered configuration. The bias piece is placed along the side of the resonators, as opposed to being beneath the resonators, as is conventional in the art. The bias piece is preferably made of a sintered rare-earth permanent magnet and has a high coercivity. Accordingly, this alarming unit has a strong resistance to demagnetization and a resistance to being shielded by metal. The bias piece has a strong anti-destruction ability, a simple structure and is easy to manufacture.

摘要翻译： 声磁（AM）防盗报警单元专门用于使用磁性分离器的硬标签防盗夹中。 警报单元包括限定空腔的谐振器壳体，其中放置有至少一个谐振器和由固定到谐振器壳体的壳体盖覆盖的偏置片。 谐振器以垂直分层的结构放置在壳体腔中。 偏置片沿着谐振器的侧面放置，与谐振器下方相反，如本领域中常规的那样。 偏置片优选由稀土类烧结永磁体制成，矫顽力高。 因此，这种报警单元具有很强的抗磁化能力和抗金属屏蔽性。 偏置片具有很强的抗破坏能力，结构简单，易于制造。

公开(公告)号：US20110217459A1

公开(公告)日：2011-09-08

申请号：US11974970

申请日：2007-10-16

申请人： Basil I. Swanson ,  Clifford J. Unkefer ,  Jurgen G. Schmidt ,  Scott M. Reed ,  John E. Shively ,  Lin Li

发明人： Basil I. Swanson ,  Clifford J. Unkefer ,  Jurgen G. Schmidt ,  Scott M. Reed ,  John E. Shively ,  Lin Li

IPC分类号： B05D5/06

CPC分类号： G01N33/5432

摘要： A process is provided of conjugating a recognition element such as a biomolecule to a hydrophobic multifunctional linker molecule by incorporating a multifunctional linker molecule including one or more anchoring groups, a reporter group and a reactive site thereon into a membrane, and, reacting the membrane including the incorporated multifunctional linker molecule with a pre-selected recognition element to form a covalently bound recognition element-multifunctional linker molecule-membrane assembly. Also, a chemical assembly suitable for subsequent covalent attachment of a recognition element is provided such assembly including a multifunctional linker molecule including one or more anchoring groups, a reporter group, and a hydrophilic spacer terminated by a reactive group capable of subsequent covalent bonding, the one or more anchoring groups incorporated in a membrane.

摘要翻译： 提供了通过将包括一个或多个锚定基团，报道基团和反应位点的多官能连接分子掺入到膜中，使识别元件例如生物分子与疏水多功能连接分子结合的方法， 所引入的多功能连接分子具有预选的识别元件以形成共价结合的识别元件 - 多功能连接子分子 - 膜组件。 此外，提供适于随后共价连接识别元件的化学组合物，其包括包含一个或多个锚定基团的多官能连接分子，报道基团和由能够随后共价键合的反应性基团封端的亲水性间隔基 一个或多个结合在膜中的锚定基团。

公开(公告)号：US07903242B2

公开(公告)日：2011-03-08

申请号：US12889823

申请日：2010-09-24

申请人： Richard Karl Fenrich ,  Lin Li

发明人： Richard Karl Fenrich ,  Lin Li

IPC分类号： G06K9/74

CPC分类号： G06K9/00046

摘要： A fingerprint imaging system configured to capture an image of a friction ridge pattern of a subject (e.g., a fingerprint, a palm print, a hand print, a footprint, etc.). The system may include one or more components that reduce the impact of ambient light on the performance of the system. In some implementations, the system may reduce the impact of ambient light without requiring additional power (e.g., to generate an increased amount of radiation) and without including “external” hoods and/or covers designed to block ambient light prior to the ambient light entering system. Instead, the system may reduce the impact of ambient light on performance by blocking ambient light internally within the system along an optical path of radiation used to electronically capture an image of the friction ridge pattern.

公开(公告)号：US20110013174A1

公开(公告)日：2011-01-20

申请号：US12889823

申请日：2010-09-24

申请人： Richard Karl FENRICH ,  Lin Li

发明人： Richard Karl FENRICH ,  Lin Li

IPC分类号： G06K9/74

CPC分类号： G06K9/00046

摘要： A fingerprint imaging system configured to capture an image of a friction ridge pattern of a subject (e.g., a fingerprint, a palm print, a hand print, a footprint, etc.). The system may include one or more components that reduce the impact of ambient light on the performance of the system. In some implementations, the system may reduce the impact of ambient light without requiring additional power (e.g., to generate an increased amount of radiation) and without including “external” hoods and/or covers designed to block ambient light prior to the ambient light entering system. Instead, the system may reduce the impact of ambient light on performance by blocking ambient light internally within the system along an optical path of radiation used to electronically capture an image of the friction ridge pattern.

公开(公告)号：US07864416B2

公开(公告)日：2011-01-04

申请号：US12072348

申请日：2008-02-26

申请人： Jianguo Huang ,  Lin Li ,  Jiandong Yang ,  Weimin Ma

发明人： Jianguo Huang ,  Lin Li ,  Jiandong Yang ,  Weimin Ma

IPC分类号： G02B23/00

CPC分类号： G02B23/06 ,  F16M11/10 ,  F16M11/22 ,  F16M11/28 ,  F16M11/34 ,  F16M2200/027

摘要： A portable astronomical telescope includes the cylinder body, on which three telescopic legs are hinged through a joint to form a tripod stand. The bottom of aforementioned cylinder body is fixed by means of connection element and mounted with part box. On the bottom end of this part box, a bottom cover is insert-mounted. On the upper end of the part box, limit connection elements of the connected telescopic leg are hinged. Within the aforementioned cylinder body, a guide bush is fixed and installed, inside of which telescope base is mounted. On the side of this telescope base, a guide pin is established. On the side of the guide sleeve, an L-shaped feed-through slot is established to accommodate the guide sleeve. On the tail end of the above feed-through slot, one guide pin residence slot is connected. The aforementioned telescope base is activated by the lug and mounted with bellows. This product can be used without need for separate assembly, and eliminates the need for a separate package. With small volume and light-weight features, it can hide the bellows within the cylinder body, in order to provide protection, which facilitates the product carrying and movement, particularly suitable for astronomy enthusiasts at the time of outdoor observation activities.

摘要翻译： 便携式天文望远镜包括气缸体，三个伸缩腿通过接头铰接在其上，形成三脚架。 上述缸体的底部通过连接元件固定，并安装有零件箱。 在该部件盒的底端，底盖是插入式安装的。 在零件盒的上端，连接的伸缩腿的限位连接元件铰接。 在上述筒体内，固定安装导向衬套，其内安装有望远镜底座。 在这个望远镜底座的一侧，建立了一个导销。 在引导套筒的一侧，建立一个L形馈通槽以容纳引导套筒。 在上述馈通槽的尾端连接有一个导销固定槽。 上述望远镜基座由凸耳激活并安装有波纹管。 本产品无需单独组装即可使用，无需单独包装。 具有体积小，重量轻的特点，可以隐藏气缸体内的波纹管，以提供保护，便于产品携带和移动，特别适合于户外观察活动时的天文爱好者。

公开(公告)号：US07816538B2

公开(公告)日：2010-10-19

申请号：US12509190

申请日：2009-07-24

申请人： Patrick G. Harran ,  Xiaodong Wang ,  Jef K. De Brabander ,  Lin Li ,  Ranny Mathew Thomas ,  Hidetaka Suzuki

发明人： Patrick G. Harran ,  Xiaodong Wang ,  Jef K. De Brabander ,  Lin Li ,  Ranny Mathew Thomas ,  Hidetaka Suzuki

IPC分类号： C07D249/04 ,  C07D257/04 ,  A61K31/41 ,  A61K31/42

CPC分类号： C07D413/14 ,  A61K31/41 ,  A61K31/422 ,  C07D207/08 ,  C07D401/10 ,  C07D403/10 ,  C07D403/14 ,  C07D405/10 ,  C07D409/10 ,  C07D413/04 ,  C07D413/06 ,  C07D413/10 ,  C07D417/04 ,  C07D417/10 ,  C07D417/14 ,  C07D495/04 ,  C07K5/06026 ,  C07K5/06034

摘要： Caspase activity and apoptosis are promoted using active, dimeric Smac peptide mimetics of the general formula M1-L-M2, wherein moieties M1 and M2 are monomeric Smac mimetics and L is a covalent linker. Target cancerous or inflammatory cells are contacted with an effective amount of an active, dimeric Smac mimetic, and a resultant increase in apoptosis of the target cells is detected. The contacting step may be effected by administering to a pharmaceutical composition comprising a therapeutically effective amount of The compoundic mimetic, wherein the individual may be subject to concurrent or antecedent radiation or chemotherapy for treatment of a neoproliferative pathology.

摘要翻译： 使用通式M1-L-M2的活性二聚体Smac肽模拟物促进胱天蛋白酶活性和凋亡，其中部分M1和M2是单体Smac模拟物，L是共价连接体。 靶向癌性或炎性细胞与有效量的活性二聚体Smac模拟物接触，并且检测到靶细胞凋亡的最终增加。 接触步骤可以通过给予包含治疗有效量的复合模拟物的药物组合物来实现，其中个体可以同时或先前放射或化疗用于治疗新生血管病变。

公开(公告)号：US20100008969A1

公开(公告)日：2010-01-14

申请号：US12216718

申请日：2008-07-10

申请人： Yi Li ,  Jiashen Li ,  Junyan Hu ,  Lin Li

发明人： Yi Li ,  Jiashen Li ,  Junyan Hu ,  Lin Li

IPC分类号： A61F2/00 ,  A61K38/17

CPC分类号： A61L27/227 ,  A61L27/18 ,  A61L27/56 ,  C08L67/04

摘要： The present invention relates to methods for preparing porous natural or synthetic material scaffolds with keratin for improving cell affinity.

摘要翻译： 本发明涉及用于改善细胞亲和力的用于制备具有角蛋白的多孔天然或合成材料支架的方法。

公开(公告)号：US20090281155A1

公开(公告)日：2009-11-12

申请号：US12509218

申请日：2009-07-24

申请人： Patrick G. Harran ,  Xiaodong Wang ,  Jef K. De Brabander ,  Lin Li ,  Ranny Mathew Thomas ,  Hidetaka Suzuki

发明人： Patrick G. Harran ,  Xiaodong Wang ,  Jef K. De Brabander ,  Lin Li ,  Ranny Mathew Thomas ,  Hidetaka Suzuki

IPC分类号： A61K31/421 ,  C07D257/04 ,  A61K31/41 ,  C07D263/08 ,  C12Q1/02 ,  A61P35/00 ,  A61P37/06

CPC分类号： C07D413/14 ,  A61K31/41 ,  A61K31/422 ,  C07D207/08 ,  C07D401/10 ,  C07D403/10 ,  C07D403/14 ,  C07D405/10 ,  C07D409/10 ,  C07D413/04 ,  C07D413/06 ,  C07D413/10 ,  C07D417/04 ,  C07D417/10 ,  C07D417/14 ,  C07D495/04 ,  C07K5/06026 ,  C07K5/06034

摘要： Caspase activity and apoptosis are promoted using active, dimeric Smac peptide mimetics of the general formula M1-L-M2, wherein moieties M1 and M2 are monomeric Smac mimetics and L is a covalent linker. Target cancerous or inflammatory cells are contacted with an effective amount of an active, dimeric Smac mimetic, and a resultant increase in apoptosis of the target cells is detected. The contacting step may be effected by administering to a pharmaceutical composition comprising a therapeutically effective amount of The compoundic mimetic, wherein the individual may be subject to concurrent or antecedent radiation or chemotherapy for treatment of a neoproliferative pathology.

公开(公告)号：US07541196B2

公开(公告)日：2009-06-02

申请号：US11172244

申请日：2005-06-29

申请人： Jennifer S. Martinez ,  Basil I. Swanson ,  John E. Shively ,  Lin Li

发明人： Jennifer S. Martinez ,  Basil I. Swanson ,  John E. Shively ,  Lin Li

IPC分类号： G01N33/551

CPC分类号： B82Y30/00 ,  B82Y15/00 ,  G01N33/57473 ,  G01N2610/00 ,  Y10S436/805

摘要： An assay element is described including recognition ligands adapted for binding to carcinoembryonic antigen (CEA) bound to a film on a single mode planar optical waveguide, the film from the group of a membrane, a polymerized bilayer membrane, and a self-assembled monolayer containing polyethylene glycol or polypropylene glycol groups therein and an assay process for detecting the presence of CEA is described including injecting a possible CEA-containing sample into a sensor cell including the assay element, maintaining the sample within the sensor cell for time sufficient for binding to occur between CEA present within the sample and the recognition ligands, injecting a solution including a reporter ligand into the sensor cell; and, interrogating the sample within the sensor cell with excitation light from the waveguide, the excitation light provided by an evanescent field of the single mode penetrating into the biological target-containing sample to a distance of less than about 200 nanometers from the waveguide thereby exciting any bound reporter ligand within a distance of less than about 200 nanometers from the waveguide and resulting in a detectable signal.

摘要翻译： 描述了一种测定元件，其包括适于结合到单模平面光波导上与膜结合的癌胚抗原（CEA）的识别配体，来自膜组的膜，聚合双层膜和含有 描述了其中的聚乙二醇或聚丙二醇基团，并且描述了用于检测CEA存在的测定方法，包括将可能的含CEA的样品注入到包含测定元件的传感器单元中，将样品保持在传感器单元内足以结合发生的时间 在样品中存在的CEA和识别配体之间，将包含报道分子配体的溶液注入到传感器单元中; 并且使用来自波导的激发光来询问传感器单元内的样本，由单一模式的消逝场提供的激发光穿透到含生物靶标的样品中，距离波导的距离小于约200纳米，由此令人兴奋 距离波导小于约200纳米的范围内的任何结合的报道配体，并产生可检测的信号。

公开(公告)号：US20080246952A1

公开(公告)日：2008-10-09

申请号：US11733080

申请日：2007-04-09

申请人： Richard Karl Fenrich ,  Lin Li

发明人： Richard Karl Fenrich ,  Lin Li

IPC分类号： G06K9/74

CPC分类号： G06K9/00046

摘要： A fingerprint imaging system configured to capture an image of a friction ridge pattern of a subject (e.g., a fingerprint, a palm print, a hand print, a footprint, etc.). The system may include one or more components that reduce the impact of ambient light on the performance of the system. In some implementations, the system may reduce the impact of ambient light without requiring additional power (e.g., to generate an increased amount of radiation) and without including “external” hoods and/or covers designed to block ambient light prior to the ambient light entering system. Instead, the system may reduce the impact of ambient light on performance by blocking ambient light internally within the system along an optical path of radiation used to electronically capture an image of the friction ridge pattern.

摘要翻译： 一种被配置为捕获被摄体的摩擦脊图案（例如，指纹，手掌印刷，手印，印记等）的图像的指纹成像系统。 该系统可以包括减少环境光对系统性能的影响的一个或多个组件。 在一些实施方案中，系统可以减少环境光的影响，而不需要额外的功率（例如，产生增加的辐射量），并且不包括设计成在环境光进入之前阻挡环境光的“外部”罩和/或盖 系统。 相反，系统可以通过沿着用于电子捕获摩擦脊图案的图像的辐射光路阻挡系统内的环境光来减小环境光对性能的影响。