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公开(公告)号:US20230024262A1
公开(公告)日:2023-01-26
申请号:US17883518
申请日:2022-08-08
发明人: Yongjin Xu , Timothy C. Dunn , Gary Hayter
IPC分类号: A61B5/145 , A61B5/00 , A61M5/172 , G16H20/17 , A61B5/1486 , G01N33/557 , G01N33/72
摘要: Methods, devices, and systems may use a kinetic model to determine physiological parameters related to the kinetics of red blood cell glycation, elimination, and generation. Such physiological parameters can be used, for example, to determine a more reliable calculated HbA1c. In another example, a method may comprise: receiving a plurality of glucose levels over a time period; receiving a glycated hemoglobin (HbA1c) level corresponding to an end of the time period; determining at least one physiological parameter selected from the group consisting of: a red blood cell glycation rate constant (kgly), a red blood cell generation rate constant (kgen), a red blood cell elimination constant (kage), and an apparent glycation constant (K), based on (1) the plurality of glucose levels and (2) the HbA1c level; and adjusting a glucose level target based on the at least one physiological parameter.
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公开(公告)号:US20230000400A1
公开(公告)日:2023-01-05
申请号:US17942684
申请日:2022-09-12
发明人: Mohammad E. Moein , Louis G. Pace , Udo Hoss , Phu X. Le , Samuel Mason Curry
IPC分类号: A61B5/1486 , A61B5/00 , A61B5/145 , A61B5/1468 , A61B5/1473 , H05K3/32
摘要: Glucose monitoring devices and related systems and methods, the glucose monitoring devices including a sensor electronics unit having a housing and a printed circuit board disposed within the housing, a transcutaneous glucose sensor assembly, and a conductive sensor connector. The printed circuit board includes a first electrical contact, the transcutaneous glucose sensor assembly includes a distal portion having a working electrode and proximal portion having a working-electrode contact in electrical communication with the working electrode, and the conductive sensor connector electrically connects the working-electrode contact with the first electrical contact. Further, the conductive sensor connector extends through a hole in the proximal portion of the transcutaneous glucose sensor assembly and through a hole in the printed circuit board.
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公开(公告)号:US20220409053A1
公开(公告)日:2022-12-29
申请号:US17847001
申请日:2022-06-22
发明人: Marc B. Taub , Namvar Kiaie
IPC分类号: A61B5/00
摘要: Embodiments described herein include a medical monitoring system with a cloud communication interface in which individual components of the medical monitoring system, including medical sensors and data receiving devices are configured to communicate with remote cloud servers of the medical monitoring system using cellular networks. The remote cloud servers process medical data reported by the medical sensors and deliver data to the data receiving devices. The components of the medical monitoring system are low-cost and durable. The sensors are considered disposable after the expiration of their active use lifetime. The data receiving device can be manufactured using low-cost durable components to be protected against loss caused by accidental damage, destruction, or misplacement. Embodiments described herein further provide for authentication and for secure communication among the components of the medical monitoring system.
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54.
公开(公告)号:US11534089B2
公开(公告)日:2022-12-27
申请号:US17557534
申请日:2021-12-21
发明人: Marc B. Taub , Jai Karan , Annie C. Tan , Timothy C. Dunn , Joel M. Goldsmith , Christine M. Neuhaus , Stephen A. Rossi , Sujit R. Jangam
IPC分类号: A61B5/1473 , A61B5/145 , G01N33/487 , A61B5/00
摘要: Analyte monitoring systems, devices, and methods associated with analyte monitoring devices, and devices incorporating the same are provided. Various graphical user interfaces (GUI) and navigation flows are provided for performing various features, activities, functions, etc., associated with the analyte monitoring device or system. Intuitive navigation is provided to enhance the interpretation of analyte measurements.
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55.
公开(公告)号:US20220389475A1
公开(公告)日:2022-12-08
申请号:US17818912
申请日:2022-08-10
IPC分类号: C12Q1/00 , C12Q1/26 , G01N27/327 , C12N11/082 , G01N33/573 , G01N33/66
摘要: NADP-dependent oxidoreductase compositions, and electrodes, sensors and systems that include the same. Analyte sensors include an electrode having a sensing layer disposed thereon, the sensing layer comprising a polymer and an enzyme composition distributed therein. The enzyme composition includes nicotinamide adenine dinucleotide phosphate (NAD(P)+) or derivative thereof; an NAD(P)+-dependent dehydrogenase; an NAD(P)H oxidoreductase; and an electron transfer agent comprising a transition metal complex.
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公开(公告)号:US20220372542A1
公开(公告)日:2022-11-24
申请号:US17763647
申请日:2020-10-01
发明人: Anthony Muerhoff , Thomas Leary , Christopher Marohnic , Barry Kreutz , Josie Corby , Benjamin Feldman , Tianmei Ouyang , Ahmed Wali , Oscar Alvizo
摘要: Compositions of matter, methods, devices, systems and apparatus for detecting analytes are disclosed including, for example, protein switches and their use in an in vivo sensor. The protein switch can be used to determine a level of an analyte that is diagnostic for health and/or well-being of a subject.
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公开(公告)号:US20220338803A1
公开(公告)日:2022-10-27
申请号:US17725063
申请日:2022-04-20
发明人: Panganamala Ashwin Kumar , Kimberly Hilton , Jessica Rose Floeh , Andrew M. Revoltar , Lindsey C. Swinehart , Vyshnnavi Parthasarathy , Addison Veronica Edwards-Gillas , Jonathan M. Fern , Matthew T. Novak , Gary A. Hayter
摘要: Systems, devices and methods are provided for incorporating a medication delivery device into an integrated management system. The integrated management system may be an integrated diabetes management system and may include a glucose monitor, a connected insulin pen, and software. The integrated management system may produce a plurality of reports that may include data related to analyte levels (e.g., glucose levels) and medication delivered (e.g., insulin delivered).
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公开(公告)号:US20220338763A1
公开(公告)日:2022-10-27
申请号:US17862303
申请日:2022-07-11
发明人: Mark ESHOO , Benjamin FELDMAN , Tianmei OUYANG , Lam TRAN
IPC分类号: A61B5/1473 , C12Q1/00 , C12Q1/46 , A61B5/00 , A61B5/1486
摘要: In vivo monitoring devices and systems for enzymes and/or analytes including devices having a reactant reservoir are provided.
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公开(公告)号:US11471075B2
公开(公告)日:2022-10-18
申请号:US17715922
申请日:2022-04-07
发明人: Thomas A. Peyser , Adam Heller
IPC分类号: A61B5/1486 , A61B5/1473 , A61B5/145 , A61B5/00
摘要: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor.
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公开(公告)号:USD966333S1
公开(公告)日:2022-10-11
申请号:US29768559
申请日:2021-01-29
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