Potentiometric diagnosis of cancer in vivo
    51.
    发明授权
    Potentiometric diagnosis of cancer in vivo 失效
    体内电位电位诊断

    公开(公告)号:US4407300A

    公开(公告)日:1983-10-04

    申请号:US168018

    申请日:1980-07-14

    申请人: Robert E. Davis

    发明人: Robert E. Davis

    IPC分类号: A61B5/05

    CPC分类号: A61B5/415 A61B5/05 A61B5/418

    摘要: Methods for scanning and diagnosing the presence or absence of malignant cancerous tissue in areas such as mammary tissue and lymph nodes of human and animal bodies by measuring the electromotive force generated by a platinum electrode or probe in contact with skin or subcutaneous portions of a body area to be diagnosed for presence or absence of said malignant tissue, and recording as suspect areas of malignant growth at least those body areas which were in contact with the probe or electrode when a significant negative electromotive force in the order of minus two millivolts or less was measured, the electromotive force being measured across two electrodes or probes, one in contact with normal skin or tissue, and the other in contact with skin or subcutaneous portions of the body area to be diagnosed.

    摘要翻译: 通过测量与身体区域的皮肤或皮下部分接触的铂电极或探针产生的电动势来扫描和诊断在人和动物体的乳腺组织和淋巴结等区域中存在或不存在恶性癌组织的方法 被诊断为存在或不存在所述恶性组织,并且当负2毫伏或更小数量级的显着负电动势为至少那些与探针或电极接触的身体区域时,记录为恶性生长的可疑区域 测量时,在两个电极或探针之间测量电动势,一个与正常皮肤或组织接触,另一个与要诊断的身体区域的皮肤或皮下部分接触。

    Bobbin carrier
    52.
    发明授权
    Bobbin carrier 失效
    绕线架

    公开(公告)号:US4261532A

    公开(公告)日:1981-04-14

    申请号:US83462

    申请日:1979-10-10

    IPC分类号: D01H1/18 B65H49/02 D02H1/00

    CPC分类号: D01H1/18 D04B15/42

    摘要: A bobbin carrier includes a rectangular frame having adjustable support shafts mounted at the corners thereof which, in turn, individually adjustably support brackets, each of which includes means for adjustably and slidably positioning thereon a pair of support rods adapted to receive large yarn bobbins. Yarn bobbins supported upon the carrier are selectively aligned, and spaced uniform distances from generally centrally located first guide means resulting in uniformity of feed of yarns to a machine which utilizes the yarns. Bobbins may be replaced by slidably retracting the support rods relative to the bobbin and the brackets.

    摘要翻译: 筒管架包括:矩形框架,其具有安装在其角部的可调节的支撑轴,该矩形框架又独立地可调节地支撑支架,每个支架包括用于可调节地和可滑动地定位在其上的适于接收大的纱线筒的一对支撑杆的装置。 支撑在载体上的纱线线轴被选择性地对齐,并且与通常位于中心的第一引导装置间隔开均匀的距离,导致纱线进给使用纱线的机器的均匀性。 可以通过相对于线轴和支架滑动地缩回支撑杆来代替线轴。

    Process for the hydroconversion of coal
    53.
    发明授权
    Process for the hydroconversion of coal 失效
    煤的加氢转化工艺

    公开(公告)号:US4189372A

    公开(公告)日:1980-02-19

    申请号:US907933

    申请日:1978-05-22

    IPC分类号: C10G1/00 C10G1/06

    CPC分类号: C10G1/006

    摘要: This invention relates to a process for producing coal derived, hydrogen-rich donor fractions from fractions of coal liquefaction products for use in the hydroconversion of coal. Coal liquefaction products are subjected to a critical solvent deashing process to produce various deashed coal fractions which can only be obtained by practicing that process. Thereafter, the various deashed coal fractions are subjected to hydrogen addition to produce heretofore unavailable hydrogen-rich donor fractions. These hydrogen-rich donor fractions may be recycled to supplant a portion of the liquefaction process solvent or blended with other fractions produced by the deashing process to provide improved fuel products.

    摘要翻译: 本发明涉及从用于煤的加氢转化的煤液化产物的馏分中生产来自煤的富氢供体部分的方法。 对煤液化产物进行临界溶剂除冰过程,以生产各种除渣的煤馏分,只能通过实践该方法获得。 此后,将各种除渣煤馏分进行氢加成以产生迄今为止不可获得的富含氢的供体部分。 这些富氢的供体部分可以被再循环以取代液化过程溶剂的一部分或与通过除冰过程产生的其它馏分混合以提供改进的燃料产物。

    Method of improving yield in a coal liquefaction product deashing process
    54.
    发明授权
    Method of improving yield in a coal liquefaction product deashing process 失效
    提高煤液化产品脱灰过程中产量的方法

    公开(公告)号:US4164466A

    公开(公告)日:1979-08-14

    申请号:US888284

    申请日:1978-03-20

    IPC分类号: C10G1/04 C10G29/20

    CPC分类号: C10G1/045

    摘要: A coal deashing process wherein a feed mixture comprising soluble coal products, insoluble coal products and solvent is separated in a first separation zone into a first heavy phase and a first light phase comprising soluble coal products, solvent and some insoluble coal products. The first light phase is withdrawn and introduced into a second separation zone wherein it separates into a second heavy phase comprising insoluble coal products, soluble coal products and some solvent and a second light phase comprising soluble coal products and solvent. The second heavy phase is withdrawn and at least a portion is recycled to the first separation zone to increase the yield of separable soluble coal products ultimately recovered by the process. In alternate embodiments, additional solvent can be added to the first light phase before introduction into the second separation zone or the recycled portion of the second heavy phase may be introduced into a treatment zone before reintroduction into the first separation zone. The treatment zone effects an increase in the molecular weight of at least a portion of the recycled second heavy phase which facilitates subsequent separation in the first separation zone.

    摘要翻译: 一种煤脱渣方法,其中将包含可溶性煤产物,不溶性煤产物和溶剂的进料混合物在第一分离区中分离成第一重相和包含可溶性煤产物,溶剂和一些不溶性煤产品的第一轻相。 将第一轻相取出并引入第二分离区,其中其分离成包含不溶性煤产物,可溶性煤产物和一些溶剂的第二重相,以及包含可溶性煤产物和溶剂的第二轻相。 第二重相被取出,并且至少一部分被再循环到第一分离区,以增加最终通过该方法回收的可分离的可溶性煤产品的产率。 在替代实施方案中,可以在引入第二分离区之前将另外的溶剂加入到第一轻相中,或者可以在重新引入第一分离区之前将第二重相的再循环部分引入处理区。 处理区域使再循环的第二重质相的至少一部分的分子量增加,这有助于在第一分离区域中随后的分离。

    Cross connect panel having slide switches and bus bar construction
    55.
    发明授权
    Cross connect panel having slide switches and bus bar construction 失效
    具有滑动开关和母线结构的交叉连接面板

    公开(公告)号:US4119816A

    公开(公告)日:1978-10-10

    申请号:US746719

    申请日:1976-12-02

    申请人: Robert E. Davis

    发明人: Robert E. Davis

    IPC分类号: H01H13/70 H01H9/00

    CPC分类号: H01H13/70

    摘要: A cross connect panel having a switchable slider assembly for positive engagement and disengagement of the loads to the supply buses. A resilient detent mechanism is provided for positive indexing of the slider assembly in alignment position with the various supply buses. The parallel supply buses are held in place by a system of bus holders and interlocking spacers and the bus bar assembly is held together by bolts through the interlocking spacers, thereby avoiding the necessity of drilling bolt holes in the bus bars and providing proper insulation therefor.

    摘要翻译: 具有可切换滑块组件的交叉连接面板,用于将负载正向接合和分离到供应总线。 提供弹性制动机构,用于使滑块组件与各种供应总线对准的位置正向分度。 并联供电总线通过总线保持器和互锁间隔件的系统保持在适当位置,母线组件通过螺栓通过互锁间隔件保持在一起,从而避免了在母线中钻螺栓孔并提供适当的绝缘。

    Method of catalyst preparation for use in suppressing hydrocarbon and
carbon monoxide emission from internal combustion engines
    56.
    发明授权
    Method of catalyst preparation for use in suppressing hydrocarbon and carbon monoxide emission from internal combustion engines 失效
    用于抑制来自内燃机的烃和一氧化碳排放的催化剂制备方法

    公开(公告)号:US4087384A

    公开(公告)日:1978-05-02

    申请号:US752319

    申请日:1976-12-20

    申请人: Robert E. Davis

    发明人: Robert E. Davis

    IPC分类号: B01D53/94 B01J23/44 B01J23/42

    CPC分类号: B01D53/944 B01J23/44

    摘要: A method of lowering undesirable vehicle exhaust emissions includes preparing a catalyst for use in the exhaust stream of the vehicle. The method includes impregnating one group of alumina substrates with platinum, impregnating another group of alumina substrates with palladium, and the mixing the first and second groups of impregnated substrates.

    摘要翻译: 减少不期望的车辆废气排放的方法包括制备用于车辆排气流中的催化剂。 该方法包括用铂浸渍一组氧化铝衬底,用钯浸渍另一组氧化铝衬底,并混合第一组和第二组浸渍衬底。

    SELECTIVE SEROTONIN 2A/2C RECEPTOR INVERSE AGONISTS AS THERAPEUTICS FOR NEURODEGENERATIVE DISEASES
    57.
    发明申请
    SELECTIVE SEROTONIN 2A/2C RECEPTOR INVERSE AGONISTS AS THERAPEUTICS FOR NEURODEGENERATIVE DISEASES 有权
    选择性丝氨酸蛋白酶2A / 2C受体反转激动剂作为神经病变性疾病的治疗剂

    公开(公告)号:US20120277221A1

    公开(公告)日:2012-11-01

    申请号:US13539011

    申请日:2012-06-29

    摘要: Behavioral pharmacological data with the compound of formula (I), a novel and selective 5HT2A/2C receptor inverse agonist, demonstrate in vivo efficacy in models of psychosis and dyskinesias. This includes activity in reversing MK-801 induced locomotor behaviors, suggesting that this compound may be an efficacious anti-psychotic, and activity in an MPTP primate model of dyskinesias, suggesting efficacy as an anti-dyskinesia agent. These data support the hypothesis that 5HT2A/2C receptor inverse agonism may confer antipsychotic and anti-dyskinetic efficacy in humans, and indicate a use of the compound of formula (I) and related agents as novel therapeutics for Parkinson's Disease, related human neurodegenerative diseases, and psychosis.

    摘要翻译: 与式(I)化合物(一种新型和选择性的5HT2A / 2C受体反向激动剂)的行为药理学数据证明了在精神病和运动障碍模型中的体内功效。 这包括逆转MK-801诱导的运动行为的活动,表明该化合物可能是MPTP灵长类运动障碍模型中有效的抗精神病药和活性,表明作为抗运动障碍剂的功效。 这些数据支持5HT2A / 2C受体反向激动作用可能赋予人类抗精神病和抗运动障碍功效的假说,并表明使用式(I)化合物和相关药物作为帕金森病,相关人类神经变性疾病的新疗法, 和精神病。

    Selective Serotonin 2A/2C Receptor Inverse Agonists as Therapeutics for Neurodegenerative Diseases
    59.
    发明申请
    Selective Serotonin 2A/2C Receptor Inverse Agonists as Therapeutics for Neurodegenerative Diseases 有权
    选择性5-羟色胺2A / 2C受体反向激动剂作为治疗神经退行性疾病

    公开(公告)号:US20100227885A1

    公开(公告)日:2010-09-09

    申请号:US12759662

    申请日:2010-04-13

    IPC分类号: A61K31/4468 A61P25/28

    摘要: Behavioral pharmacological data with the compound of formula (I), a novel and selective 5HT2A/2C receptor inverse agonist, demonstrate in vivo efficacy in models of psychosis and dyskinesias. This includes activity in reversing MK-801 induced locomotor behaviors, suggesting that this compound may be an efficacious anti-psychotic, and activity in an MPTP primate model of dyskinesias, suggesting efficacy as an anti-dyskinesia agent. These data support the hypothesis that 5HT2A/2C receptor inverse agonism may confer antipsychotic and anti-dyskinetic efficacy in humans, and indicate a use of the compound of formula (I) and related agents as novel therapeutics for Parkinson's Disease, related human neurodegenerative diseases, and psychosis.

    摘要翻译: 与式(I)化合物(一种新型和选择性的5HT2A / 2C受体反向激动剂)的行为药理学数据证明了在精神病和运动障碍模型中的体内功效。 这包括逆转MK-801诱导的运动行为的活动,表明该化合物可能是MPTP灵长类运动障碍模型中有效的抗精神病药和活性,表明作为抗运动障碍剂的功效。 这些数据支持5HT2A / 2C受体反向激动作用可能赋予人类抗精神病和抗运动障碍功效的假说,并表明使用式(I)化合物和相关药物作为帕金森病,相关人类神经变性疾病的新疗法, 和精神病。