公开(公告)号：US08703953B2

公开(公告)日：2014-04-22

申请号：US13777144

申请日：2013-02-26

Applicant: Bristol-Myers Squibb Company

Inventor： Vivekananda M. Vrudhula ,  Senliang Pan ,  Ramkumar Rajamani ,  John E. Macor ,  Joanne J. Bronson ,  Carolyn Diane Dzierba ,  Susheel Jethanand Nara ,  Maheswaran Sivasamban Karatholuvhu

IPC: A61K31/44 ,  C07D491/00

CPC classification number: C12N9/99 ,  C07D491/04 ,  C07D491/052 ,  C07D491/20

Abstract: The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.

Abstract translation: 本公开一般涉及可以抑制AAK1（衔接子相关激酶1），包含这些化合物的组合物和抑制AAK1的方法的化合物。

公开(公告)号：US20130237555A1

公开(公告)日：2013-09-12

申请号：US13777144

申请日：2013-02-26

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Vivekananda M. Vrudhula ,  Senliang Pan ,  Ramkumar Rajamani ,  John E. Macor ,  Joanne J. Bronson ,  Carolyn Diane Dzierba ,  Susheel Jethanand Nara ,  Maheswaran Sivasamban Karatholuvhu

IPC: C07D491/052 ,  C12N9/99 ,  C07D491/20

CPC classification number: C12N9/99 ,  C07D491/04 ,  C07D491/052 ,  C07D491/20

Abstract: The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.

Abstract translation: 本公开一般涉及可以抑制AAK1（衔接子相关激酶1），包含这些化合物的组合物和抑制AAK1的方法的化合物。