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公开(公告)号：US20080154351A1
公开(公告)日：2008-06-26
申请号：US11850885
申请日：2007-09-06
申请人： Alan R. Leewood , David D. Grewe , Mark J. Hiatt , Anthony O. Ragheb , William D. Voorhees , Blayne A. Roeder , James D. Purdy
发明人： Alan R. Leewood , David D. Grewe , Mark J. Hiatt , Anthony O. Ragheb , William D. Voorhees , Blayne A. Roeder , James D. Purdy
CPC分类号： A61F2/86 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2/95 , A61F2002/825 , A61F2002/826 , A61F2002/91566 , A61F2002/91575 , A61F2002/9511 , A61F2210/0004 , A61F2220/0075 , A61F2250/0031 , A61F2250/0071
摘要： Various stent structures are provided with improved axial and torsional flexibility. One type of stent structure includes multiple segmented stent structures connected to each other by biodegradable interconnectors. A delivery system adapted to delivery the multiple segmented stents is also described. Another type of stent structure includes biodegradable connectors that are incorporated into a framework of non-biodegradable interconnecting members that form the support structure of the stent. The biodegradable connectors in both stent structures degrade or are absorbed after the stent is deployed. Stabilizing elements may be provided to the stent structures to supplement the stiffness of the stent with stability during loading and deployment.
摘要翻译： 各种支架结构具有改进的轴向和扭转弹性。 一种类型的支架结构包括通过可生物降解的互连器彼此连接的多个分段的支架结构。 还描述了适于递送多个分段支架的递送系统。 另一种类型的支架结构包括可生物降解的连接器，其被结合到形成支架的支撑结构的不可生物降解的互连构件的框架中。 支架结构中的可生物降解的连接器在支架部署后降解或被吸收。 可以将稳定元件提供给支架结构，以在加载和展开期间具有稳定性补充支架的刚度。
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52.发明授权Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists 有权用于局部递送血管紧张素II 2型受体拮抗剂的医疗装置和方法公开(公告)号：US07828840B2
公开(公告)日：2010-11-09
申请号：US12291593
申请日：2008-11-12
CPC分类号： A61F2/86 , A61F2210/0076 , A61F2220/0016 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2250/0067 , A61F2250/0068
摘要： This invention relates to medical devices and an angiotensin II type 2 (AT2) receptor antagonist compound, the medical device being adapted to release the AT2 receptor antagonist compound within a body of a patient. This invention also relates to medical devices and methods of treatment of disease, such as aneurysms and aortic dissection. Medical devices may include coated stents, grafts, stent grafts, balloons and catheters.
摘要翻译： 本发明涉及医疗装置和血管紧张素II型2型（AT2）受体拮抗剂化合物，该医疗装置适于释放患者体内的AT2受体拮抗剂化合物。 本发明还涉及医疗装置和治疗疾病的方法，例如动脉瘤和主动脉夹层。 医疗装置可以包括涂覆支架，移植物，支架移植物，气囊和导管。
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53.发明申请Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists 有权用于局部递送血管紧张素II 2型受体拮抗剂的医疗装置和方法公开(公告)号：US20090177267A1
公开(公告)日：2009-07-09
申请号：US12291593
申请日：2008-11-12
IPC分类号： A61F2/06
CPC分类号： A61F2/86 , A61F2210/0076 , A61F2220/0016 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2250/0067 , A61F2250/0068
摘要： This invention relates to medical devices and an angiotensin II type 2 (AT2) receptor antagonist compound, the medical device being adapted to release the AT2 receptor antagonist compound within a body of a patient. This invention also relates to medical devices and methods of treatment of disease, such as aneurysms and aortic dissection. Medical devices may include coated stents, grafts, stent grafts, balloons and catheters.
摘要翻译： 本发明涉及医疗装置和血管紧张素II型2型（AT2）受体拮抗剂化合物，该医疗装置适于释放患者体内的AT2受体拮抗剂化合物。 本发明还涉及医疗装置和治疗疾病的方法，例如动脉瘤和主动脉夹层。 医疗装置可以包括涂覆支架，移植物，支架移植物，气囊和导管。
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公开(公告)号：US07799266B2
公开(公告)日：2010-09-21
申请号：US12336172
申请日：2008-12-16
申请人： Fred T. Parker , Anthony O. Ragheb
发明人： Fred T. Parker , Anthony O. Ragheb
IPC分类号： B29D23/00
CPC分类号： A61F2/95 , A61F2/958 , A61F2002/9583 , A61F2002/9665 , B29C49/44 , B29C2049/0089 , B29K2105/258 , B29L2031/7542
摘要： A method for manufacturing a stent delivery system having a holder and at least one stent configured to expand from a first diameter to a second diameter is provided. The manufacturing method includes compressing the stent to the first diameter, inserting the stent into a first tube, placing a second tube inside the first tube and inside an inner diameter of the stent. The second tube is airtight. The manufacturing method also includes applying pressure and heat suitable to the second tube, thereby blowmolding the second tube against the stent.
摘要翻译： 提供一种用于制造支架输送系统的方法，该支架输送系统具有保持器和构造成从第一直径扩展到第二直径的至少一个支架。 该制造方法包括将支架压缩到第一直径，将支架插入第一管中，将第二管置于第一管内并且在支架的内径内。 第二根管是气密的。 该制造方法还包括施加适合于第二管的压力和热量，从而将第二管道吹塑成型而抵靠支架。
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公开(公告)号：US20100148409A1
公开(公告)日：2010-06-17
申请号：US12336172
申请日：2008-12-16
申请人： Fred T. Parker , Anthony O. Ragheb
发明人： Fred T. Parker , Anthony O. Ragheb
IPC分类号： B29C49/00
CPC分类号： A61F2/95 , A61F2/958 , A61F2002/9583 , A61F2002/9665 , B29C49/44 , B29C2049/0089 , B29K2105/258 , B29L2031/7542
摘要： A method for manufacturing a stent delivery system having a holder and at least one stent configured to expand from a first diameter to a second diameter is provided. The manufacturing method includes compressing the stent to the first diameter, inserting the stent into a first tube, placing a second tube inside the first tube and inside an inner diameter of the stent. The second tube is airtight. The manufacturing method also includes applying pressure and heat suitable to the second tube, thereby blowmolding the second tube against the stent.
摘要翻译： 提供一种用于制造支架输送系统的方法，该支架输送系统具有保持器和构造成从第一直径扩展到第二直径的至少一个支架。 该制造方法包括将支架压缩到第一直径，将支架插入第一管中，将第二管置于第一管内并且在支架的内径内。 第二根管是气密的。 该制造方法还包括施加适合于第二管的压力和热量，从而将第二管道吹塑成型而抵靠支架。
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公开(公告)号：US20080033522A1
公开(公告)日：2008-02-07
申请号：US11782037
申请日：2007-07-24
IPC分类号： A61F2/06
CPC分类号： A61L31/082
摘要： Medical devices for implantation in a body vessel, and methods of using and making the same, are provided. A medical device can include a frame with a vessel-engaging region on at least a portion of the medical device. The vessel-engaging region may be a particulate coating configured and adapted to engage the interior wall of a body vessel or to attach a material, such as a valve leaflet or graft material, to the frame. Methods of making an implantable medical device and methods of treating a subject are also disclosed.
摘要翻译： 提供了用于植入体内的医疗装置及其使用和制造方法。 医疗装置可以包括在医疗装置的至少一部分上具有容器接合区域的框架。 容器接合区域可以是构造成适于接合身体容器的内壁或者将诸如阀瓣或移植材料的材料附接到框架的颗粒涂层。 还公开了制造可植入医疗装置的方法和治疗受试者的方法。
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