公开(公告)号：US20200345615A1

公开(公告)日：2020-11-05

申请号：US16934596

申请日：2020-07-21

Applicant: Colgate-Palmolive Company

Inventor： Lynette A. ZAIDEL ,  Guisheng PAN ,  Suman K. CHOPRA ,  Prakasarao MANDADI ,  Michael PRENCIPE

IPC: A61K8/81 ,  A61K8/02 ,  A61K8/22 ,  A61Q11/00 ,  A61Q11/02 ,  A61K8/24 ,  A61K8/90 ,  A61K8/49 ,  A61K8/891

Abstract: Oral care compositions comprising: (a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer (e.g., poly-N-vinyl polylactam, or poly-N-vinyl-polyimide); (b) a whitening agent (e.g., hydrogen peroxide); and (c) an orally acceptable carrier. In one embodiment, the carrier comprises a film forming material. Methods are also provided for making an oral care composition comprising: (a) mixing a whitening agent, silicone adhesive and carrier fluid to form a homogenous mixture; (b) adding a peroxide complex to said homogenous mixture, wherein said complex comprises hydrogen peroxide and an N-vinyl heterocyclic polymer; and (c) mixing under vacuum.

公开(公告)号：US20200297597A1

公开(公告)日：2020-09-24

申请号：US16897701

申请日：2020-06-10

Applicant: Colgate-Palmolive Company

Inventor： Aarti REGE ,  Michael PRENCIPE ,  Madhuleena BHADRA

IPC: A61K8/27 ,  A61K8/21 ,  A61K8/24 ,  A61K8/36 ,  A61Q11/00

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride and an organic acid buffer system, as well as methods of using the same.

公开(公告)号：US20200254286A1

公开(公告)日：2020-08-13

申请号：US16859288

申请日：2020-04-27

Applicant: Colgate-Palmolive Company

Inventor： Steven FISHER ,  Linh FRUGE ,  Michael PRENCIPE

IPC: A61Q11/00 ,  A61K8/20 ,  A61K8/24 ,  A61K8/365

Abstract: A dentifrice composition having a low water phase comprising effective amounts of polyphosphate and ionic active ingredients.

公开(公告)号：US20200170913A1

公开(公告)日：2020-06-04

申请号：US16777936

申请日：2020-01-31

Applicant: Colgate-Palmolive Company

Inventor： Marcella MOURAO ,  Wilbens JOSIAS ,  Betty WON ,  Lisa MANUS ,  Michael A. STRANICK ,  Xiaoyi HUANG ,  Michael PRENCIPE ,  Amy RUSSO ,  Hansruedi STETTLER ,  Peng YAN ,  Chengkang TAN ,  Vyoma PATEL ,  André Michelle MORGAN ,  Andrei POTANIN

IPC: A61K8/44 ,  A61K8/365 ,  A61K8/34 ,  A61K8/25 ,  A61K8/37 ,  A61K8/04 ,  A61K8/21 ,  A61K8/73 ,  A61Q11/00 ,  A61K8/27 ,  A61K8/24

Abstract: Described herein are oral care compositions comprising a basic amino acid; a combination of zinc ion sources; and from about 0.75 wt. % to about 2 wt. % of a chelating system; along with methods of making and using same.

公开(公告)号：US20200121572A1

公开(公告)日：2020-04-23

申请号：US16717459

申请日：2019-12-17

Applicant: Colgate-Palmolive Company

Inventor： Aarti REGE ,  Michael PRENCIPE

IPC: A61K8/27 ,  A61K8/365 ,  A61K8/24 ,  A61K8/44 ,  A61K8/21 ,  A61Q11/00 ,  A61K8/19

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride, an anionic polymer, and a basic amino acid, as well as methods of using the same.

公开(公告)号：US20200009031A1

公开(公告)日：2020-01-09

申请号：US16572749

申请日：2019-09-17

Applicant: Colgate-Palmolive Company

Inventor： Michael PRENCIPE ,  Yun XU ,  Xiao Yi HUANG

IPC: A61K8/27 ,  A61K8/43

Abstract: An oral care composition comprising: (a) arginine, in free or salt form; and (b) zinc oxide and zinc citrate. The oral care composition can reduce or inhibit biofilm formation in an oral cavity.

公开(公告)号：US20190275355A1

公开(公告)日：2019-09-12

申请号：US16425312

申请日：2019-05-29

Applicant: Colgate-Palmolive Company

Inventor： Ying YANG ,  Dandan CHEN ,  Robert D'AMBROGIO ,  Paul THOMSON ,  Harsh Mahendra TRIVEDI ,  Michael PRENCIPE ,  James MASTERS ,  Stanislav JARACZ

IPC: A61Q11/00 ,  A61K8/21 ,  A61Q17/00 ,  A61K8/365 ,  A61K8/35 ,  A61K8/34 ,  A61K8/22 ,  A61K36/9068 ,  A61K8/97 ,  A61K8/27 ,  A61K45/06

Abstract: This invention relates to oral care compositions comprising zingerone, bisabolol, a stannous ion source, zinc oxide, and zinc citrate, as well as to methods of using and of making these compositions.

公开(公告)号：US20190224089A1

公开(公告)日：2019-07-25

申请号：US16376185

申请日：2019-04-05

Applicant: Colgate-Palmolive Company

Inventor： Aarti REGE ,  Michael PRENCIPE

IPC: A61K8/27 ,  A61K8/24 ,  A61K8/362 ,  A61Q11/00 ,  A61K8/20 ,  A61K8/19 ,  A61K8/21

Abstract: An oral care composition comprising high water oral care compositions comprising an orally acceptable carrier, zinc phosphate, a first stannous ion source (i.e., stannous fluoride), and a second stannous ion source (i.e., stannous chloride). Methods and uses for this composition are also described throughout.

公开(公告)号：US20190125636A1

公开(公告)日：2019-05-02

申请号：US16225823

申请日：2018-12-19

Applicant: Colgate-Palmolive Company

Inventor： Michael PRENCIPE ,  Xiao Yi HUANG ,  Yuan Hui XIE

IPC: A61K8/24 ,  A61K8/21 ,  A61K8/19 ,  A61Q11/00 ,  A61K8/27 ,  A61K8/365

Abstract: The present invention relates to an oral care composition with a high water content which has improved robustness towards microbial challenge. The oral care composition includes compositions comprising from 0.125 wt % to 0.75 wt % of a water soluble source of stannous ions, wherein the composition comprises at least 50 wt % water and wherein the source of stannous ions is selected from the group consisting of stannous chloride, stannous pyrophosphate, stannous formate, stannous acetate, stannous gluconate, stannous lactate, stannous tartrate, stannous oxalate, stannous malonate, stannous citrate, stannous ethylene glyoxide, and mixtures thereof.

公开(公告)号：US20190117542A1

公开(公告)日：2019-04-25

申请号：US16225898

申请日：2018-12-19

Applicant: Colgate-Palmolive Company

Inventor： Aarti REGE ,  Michael PRENCIPE

IPC: A61K8/44 ,  A61Q11/00 ,  A61K8/365 ,  A61K8/24 ,  A61K8/27 ,  A61K8/21 ,  A61K8/35

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride, arginine or lysine and an organic acid buffer system, as well as methods of using the same.