公开(公告)号：US20120005405A1

公开(公告)日：2012-01-05

申请号：US12828241

申请日：2010-06-30

申请人： William Wu ,  Shai Traister ,  Jianmin Huang ,  Neil David Hutchison ,  Steven Sprouse

发明人： William Wu ,  Shai Traister ,  Jianmin Huang ,  Neil David Hutchison ,  Steven Sprouse

IPC分类号： G06F12/02 ,  G06F12/00

CPC分类号： G06F12/0246 ,  G06F12/0253

摘要： A method and system pre-emptively perform garbage collection operations of a forced amount on update blocks in a memory device. The amount of garbage collection needed by a certain data write is monitored and adjusted to match the forced amount if necessary. Update blocks may be selected on the basis of their recent usage or the amount of garbage collection required. Another method and system may store control information about update blocks in a temporary storage area so that a greater number of update blocks are utilized. The sequential write performance measured by the Speed Class test may be optimized by using this method and system.

摘要翻译： 一种方法和系统在存储器设备中的更新块上优先地执行强制量的垃圾回收操作。 监视和调整某些数据写入所需的垃圾回收量，以便在必要时与强制量匹配。 可以基于它们最近的使用或所需的垃圾收集量来选择更新块。 另一种方法和系统可以将关于更新块的控制信息存储在临时存储区域中，以便利用更多数量的更新块。 通过速度等级测试测量的顺序写入性能可以通过使用此方法和系统进行优化。

公开(公告)号：US07198894B2

公开(公告)日：2007-04-03

申请号：US09998481

申请日：2001-11-30

申请人： Francis Barany ,  Weiguo Cao ,  Jianmin Huang ,  Jing Lu

发明人： Francis Barany ,  Weiguo Cao ,  Jianmin Huang ,  Jing Lu

IPC分类号： C12Q1/68 ,  C12P19/34

CPC分类号： C12Q1/683 ,  C12Q2531/113 ,  C12Q2521/501 ,  C12Q2521/301

摘要： The present invention is a method for detecting DNA sequence differences including single nucleotide mutations or polymorphisms, one or more nucleotide insertions, and one or more nucleotide deletions. Labeled heteroduplex PCR fragments containing base mismatches are prepared. Endonuclease cleaves the heteroduplex PCR fragments both at the position containing the variation (one or more mismatched bases) and to a lesser extent, at non-variant (perfectly matched) positions. Ligation of the cleavage products with a DNA ligase corrects non-variant cleavages and thus substantially reduces background. This is then followed by a detection step in which the reaction products are detected, and the position of the sequence variations are determined.

摘要翻译： 本发明是检测DNA序列差异的方法，包括单核苷酸突变或多态性，一个或多个核苷酸插入和一个或多个核苷酸缺失。 制备含有碱基错配的标记的异源双链PCR片段。 核酸内切酶在含有变异（一个或多个错配碱基）的位置和较少程度上在非变体（完全匹配）位置处切割异源双链PCR片段。 用DNA连接酶连接切割产物校正非变体切割，从而大大减少背景。 然后进行检测步骤，其中检测反应产物，并确定序列变异的位置。