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公开(公告)号:US4952577A
公开(公告)日:1990-08-28
申请号:US202542
申请日:1988-06-06
申请人: Marco Alpegiani , Giovanni Franceschi , Ettore Perrone , Franco Zarini , Constantino Della Bruna
发明人: Marco Alpegiani , Giovanni Franceschi , Ettore Perrone , Franco Zarini , Constantino Della Bruna
IPC分类号: C07D499/897 , A61K31/43 , A61P31/04 , C07D499/06 , C07D499/88 , C07D499/883
CPC分类号: C07D499/88
摘要: A substantially (.gtoreq.95%) optically pure (5R,6S,1'R) penem of formula ##STR1## and the pharmaceutically acceptable salts and the ester prodrugs thereof, are endowed with antibacterial activity.