公开(公告)号：US6162258A

公开(公告)日：2000-12-19

申请号：US382331

申请日：1999-08-25

申请人： Nelson L. Scarborough ,  Todd M. Boyce

发明人： Nelson L. Scarborough ,  Todd M. Boyce

IPC分类号： A61F2/28 ,  A61F2/30 ,  A61L27/36 ,  A61F2/36

CPC分类号： A61L27/3691 ,  A61F2/28 ,  A61F2002/2817 ,  A61F2002/30677 ,  A61L27/3608 ,  A61L27/365 ,  A61L27/3687 ,  A61L2430/02 ,  A61L2430/40

摘要： Monolithic bone intended for implantation is treated in order to conserve its mechanical strength during lyophilization and subsequent packaging and to maintain the strength of the bone during the storage period preceding the rehydration and implantation of the bone. The method of treatment comprises contacting the bone with a mechanical strength-conserving amount of at least one biocompatible mechanical strength-conserving agent, the agent being a liquid organic material which is capable of penetrating and remaining in the bone during its lyophilization, packaging and storage, lyophilizing the bone containing the mechanical strength-conserving agent and packaging the lyophilized bone.

摘要翻译： 为了在冷冻干燥和随后的包装过程中保持其机械强度并在骨水泥再植和植入之前的储存期间保持骨骼的强度，处理了用于植入的单片骨。 所述处理方法包括使所述骨与机械强度保存量的至少一种生物相容性机械强度保持剂接触，所述试剂是液体有机材料，其在其冻干，包装和储存期间能够渗透并保留在骨中 冻干含有机械强度保存剂的骨并包装冻干骨。