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    Process for selecting bone for transplantation
    2.
    发明授权
    Process for selecting bone for transplantation 有权
    选择骨移植的方法

    公开(公告)号：US08750960B2

    公开(公告)日：2014-06-10

    申请号：US10519202

    申请日：2003-07-17

    申请人： Todd M. Boyce ,  Stephen N. Mercadante

    发明人： Todd M. Boyce ,  Stephen N. Mercadante

    IPC分类号： A61B5/05

    CPC分类号： A61B6/505 ,  A61B34/10 ,  A61F2002/2835 ,  A61F2002/30948

    摘要： A procedure for determining a plan for cutting a bone sample for use as an implant provides scanning the bone with a CT scanning system to provide slice images of the bone. The scanning system then determines the cortical or cancellous bone dimensions and density of the bone. Determining such dimensions and density permits accurate planning and preparation of an implant graft that is correlated to the predetermined plan without waste of bone through cutting test specimens to determine the bone parameters. Other images techniques that provide slice images are also disclosed.

    摘要翻译： 用于确定切割用作植入物的骨样品的计划的步骤提供用CT扫描系统扫描骨骼以提供骨的切片图像。 然后扫描系统确定皮质或松质骨的尺寸和骨密度。 确定这种尺寸和密度允许准确地规划和准备与预定计划相关的植入物植入物，而不会通过切割试样来浪费骨骼以确定骨骼参数。 还公开了提供切片图像的其它图像技术。

    OSTEOINDUCTIVE DEMINERALIZED CANCELLOUS BONE
    3.
    发明申请
    OSTEOINDUCTIVE DEMINERALIZED CANCELLOUS BONE 有权

    公开(公告)号：US20140065239A9

    公开(公告)日：2014-03-06

    申请号：US12140025

    申请日：2008-06-16

    申请人： Keyvan Behnam ,  Nanette Forsyth ,  James Russell ,  John M. Winterbottom ,  Todd M. Boyce

    发明人： Keyvan Behnam ,  Nanette Forsyth ,  James Russell ,  John M. Winterbottom ,  Todd M. Boyce

    IPC分类号： A61K35/32

    CPC分类号： A61K35/32 ,  A61F2/28 ,  A61F2002/2817 ,  A61F2002/30059 ,  A61F2310/00359 ,  A61L27/3608 ,  A61L27/3641 ,  A61L27/3645 ,  A61L27/3683 ,  A61L27/3687 ,  A61L27/3691 ,  A61L27/3695 ,  A61L27/3878 ,  A61L2430/02

    摘要： An osteoinductive demineralized bone matrix, corresponding osteoimplants, and methods for making the osteoinductive demineralized bone matrix are disclosed. The osteoinductive demineralized bone matrix may be prepared by providing demineralized bone and altering the collagenous structure of the bone. The osteoinductive demineralized bone matrix may also be prepared by providing demineralized bone and compacting the bone, for example via mechanical compaction, grinding into a particulate, or treatment with a chemical. Additives such as growth factors or bioactive agents may be added to the osteoinductive demineralized bone matrix. The osteoinductive demineralized bone matrix may form an osteogenic osteoimplant. The osteoimplant, when implanted in a mammalian body, may induce at the locus of the implant the full developmental cascade of endochondral bone formation including vascularization, mineralization, and bone marrow differentiation. The osteoinductive demineralized bone matrix may also be used as a delivery device to administer bioactive agents.

    摘要翻译： 公开了一种骨诱导的软骨骨架，相应的骨关节植入物以及用于制造骨诱导性软骨骨架的方法。 可以通过提供软化骨和改变骨的胶原结构来制备骨诱导的软骨骨架。 还可以通过提供脱矿质骨和压实骨，例如通过机械压实，研磨成颗粒或用化学品处理来制备骨诱导的软化骨基质。 添加剂如生长因子或生物活性剂可以加入到骨诱导的软化骨基质中。 骨诱导的骨质疏松骨质可形成成骨植骨。 当植入植入哺乳动物体内的植骨植入物可能在植入物的位置诱导软骨内骨形成的完全发育级联，包括血管化，矿化和骨髓分化。 骨诱导的软化骨基质也可以用作施用生物活性剂的递送装置。

    Non-destructive method for evaluating the strength of cancellous bone
    6.
    发明授权
    Non-destructive method for evaluating the strength of cancellous bone 有权
    用于评估松质骨强度的非破坏性方法

    公开(公告)号：US07448264B2

    公开(公告)日：2008-11-11

    申请号：US10884097

    申请日：2004-07-02

    申请人： Todd M. Boyce ,  David R. Kaes ,  Lawrence A. Shimp ,  John M. Winterbottom

    发明人： Todd M. Boyce ,  David R. Kaes ,  Lawrence A. Shimp ,  John M. Winterbottom

    IPC分类号： G01M19/00

    CPC分类号： G01N33/4833 ,  G01N2203/0089

    摘要： A non-destructive method for evaluating the strength of cancellous bone includes the steps of performing at least two of the following tests on each cancellous bone of a population of cancellous bones: a manual compression test, an apparent density test, and an appearance test; determining a compressive strength for each cancellous bone based on the two tests performed; comparing the determined compressive strength of each cancellous bone against a predetermined compressive strength requirement; and, eliminating a subset of cancellous bone from the population of cancellous bone, which subset of cancellous bone fails to meet the predetermined compressive strength requirement.

    摘要翻译： 用于评价松质骨强度的非破坏性方法包括以下步骤：对松质骨群体的每个松质骨执行以下测试中的至少两项：手动压缩试验，表观密度试验和外观试验; 基于所进行的两次测试确定每个松质骨的抗压强度; 将每个松质骨的确定的抗压强度与预定的抗压强度要求进行比较; 并且从松质骨群体中消除松质骨的子集，松质骨的哪一个子组不能满足预定的抗压强度要求。