Carboxamides
    52.
    发明授权
    Carboxamides 有权
    羧甲酰胺

    公开(公告)号:US07842710B2

    公开(公告)日:2010-11-30

    申请号:US10588491

    申请日:2005-01-22

    IPC分类号: A61K31/4155 C07D231/12

    摘要: The invention relates to novel carboxamides of formula (I), in which M represents a phenyl ring, pyridine ring or pyrimidine, pyridazine or pyrazine ring, respectively monosubstituted by R8, or represents a thiazole ring substituted by R8-A; R8 represents hydrogen, fluorine, chlorine, methyl, isopropyl, methylthio or trifluoromethyl; R8 can also represent methoxy; R8-A represents hydrogen, methyl, methylthio or trifluoromethyl; L1 represents C1-C10 alkene (alkanediyl); Q represents O, S, SO, SO2 or NR9; L2 represents a direct bond, SiR10R11 or CO; R represents hydrogen, C1-C8 alkyl, C1-C8 alkoxy, C1-C4 alkoxy-C1-C4-alkyl, C1-C4 alkylthio-C1-C4-alkyl, C2-C8 alkenyl, C2-C8 alkynyl, C1-C6 haloalkyl, C2-C6-haloalkenyl, C2-C6 haloalkynyl or C3-C6 cycloalkyl; A represents the group of formula (AI); the remaining substituents are defined in claim 1. The inventive substances have a powerful microbicidal action and can be used to control undesirable micro-organisms such as fungi and bacteria in the phyto-protection and material protection fields.

    摘要翻译: 本发明涉及式(I)的新型甲酰胺,其中M表示分别被R8单取代的苯环,吡啶环或嘧啶,哒嗪或吡嗪环,或表示被R8-A取代的噻唑环; R8代表氢,氟,氯,甲基,异丙基,甲硫基或三氟甲基; R8也可以代表甲氧基; R8-A表示氢,甲基,甲硫基或三氟甲基; L1代表C1-C10烯烃(烷二基); Q表示O,S,SO,SO 2或NR 9; L2表示直接键合,SiR 10 R 11或CO; R代表氢,C 1 -C 8烷基,C 1 -C 8烷氧基,C 1 -C 4烷氧基-C 1 -C 4 - 烷基,C 1 -C 4烷硫基-C 1 -C 4烷基,C 2 -C 8烯基,C 2 -C 8炔基,C 1 -C 6卤代烷基 ,C 2 -C 6卤代链烯基,C 2 -C 6卤代炔基或C 3 -C 6环烷基; A代表式(AI)的基团; 其余的取代基如权利要求1中所定义。本发明的物质具有强大的杀微生物作用,可用于防止植物保护和材料保护领域中的不期望的微生物如真菌和细菌。