公开(公告)号：US20210106227A1

公开(公告)日：2021-04-15

申请号：US17031182

申请日：2020-09-24

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh ,  Jeffrey M. Gillberg

IPC: A61B5/00 ,  A61B5/0408

Abstract: Systems, methods, and devices are described herein for evaluation of patient's cardiac condition based on monitored electrical activity from a plurality of external electrodes. Various information such as electrical heterogeneity information may be generated based on the monitored electrical activity, which may be further analyzed to evaluate the patient's cardiac condition. The systems, methods, and devices may provide an indication of whether the patient may benefit from cardiac therapy based on the evaluation of the patient's cardiac condition.

公开(公告)号：US20210023367A1

公开(公告)日：2021-01-28

申请号：US16521000

申请日：2019-07-24

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh

IPC: A61N1/368 ,  A61N1/375 ,  A61N1/05

Abstract: An implantable medical system may provide atrioventricular synchronous pacing using the ventricular septal wall. The system may include a ventricular electrode coupled to an intracardiac housing or a first medical lead implantable in the ventricular septal wall of the patient's heart to deliver cardiac therapy to or sense electrical activity of the left ventricle of the patient's heart and a right atrial electrode coupled to a leadlet or second medical lead to deliver cardiac therapy to or sense electrical activity of the right atrium of the patient's heart. A right ventricular electrode may be coupled to the intracardiac housing or the first medical lead and implantable in the ventricular septal wall of the patient's heart to deliver cardiac therapy to or sense electrical activity of the right ventricle of the patient's heart.

公开(公告)号：US10687722B2

公开(公告)日：2020-06-23

申请号：US15720119

申请日：2017-09-29

Applicant: Medtronic, Inc.

Inventor： Juan Du ,  Subham Ghosh ,  Jeffrey M. Gillberg

IPC: A61B5/04 ,  A61B5/0408 ,  A61B5/00 ,  A61B5/0456 ,  A61N1/365

Abstract: A system and associated method for determining whether a signal is ambiguous, wherein the system includes a plurality of electrodes configured to be located proximate tissue of a patient. A display apparatus thereof includes a graphical user interface configured to present information to a user. A computing apparatus thereof is configured to determine maximums for beats of signals from the electrodes.

公开(公告)号：US10668290B2

公开(公告)日：2020-06-02

申请号：US15909603

申请日：2018-03-01

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh

IPC: A61N1/365 ,  A61N1/02 ,  A61N1/375 ,  A61N1/372 ,  A61N1/368 ,  A61N1/37

Abstract: A method and system for delivering cardiac pacing therapy that includes sensing electrical activity of tissue of a patient from a plurality of external electrodes during delivery of a non-ambulatory pacing therapy from a pacing device and determining an optimal electromechanical (EM) response time from an optimal electrical activation determined from electrical heterogeneity information obtained during non-ambulatory pacing therapy. During delivery of subsequent ambulatory pacing, the pacing sensing an EM signal from an EM sensor of the pacing device, determines a current EM response time in response to the sensed EM signal, and adjusting a pacing parameter setting of the ambulatory pacing therapy in response to comparing the current EM response time to the optimal EM response time.

公开(公告)号：US20190290918A1

公开(公告)日：2019-09-26

申请号：US15928753

申请日：2018-03-22

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh

IPC: A61N1/37 ,  A61N1/368 ,  A61N1/02 ,  A61N1/372

Abstract: A method and system for delivering a cardiac pacing therapy that includes a cardiac signal being sensed via electrodes of an atrial lead, and an occurrence of one of an intrinsic and a paced atrial depolarization event of a current cardiac cycle being determined in response to the sensed cardiac signal. A first pacing therapy is delivered during the current cardiac cycle in response to the determined occurrence of the depolarization event, and an amplitude of the cardiac signal within the current cardiac cycle subsequent to the delivered first pacing therapy is compared to a predetermined amplitude threshold. A second pacing therapy is delivered, via a left ventricular lead, within the same cardiac cycle and subsequent to the delivered first pacing therapy in response to the amplitude not being more negative than the predetermined amplitude threshold and is not delivered in response to the amplitude being more negative than the predetermined amplitude threshold.

公开(公告)号：US20190290909A1

公开(公告)日：2019-09-26

申请号：US15934517

申请日：2018-03-23

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh ,  Zhongping Yang

IPC: A61N1/368 ,  A61B5/0408 ,  A61N1/365 ,  A61N1/37 ,  A61N1/362

Abstract: Cardiac electrical heterogeneity information may be used to determine whether one or more ventricle from atrium (VfA) paced settings for VfA pacing therapy are acceptable. Cardiac electrical heterogeneity information may be generated during VfA pacing, and then evaluated to determine whether the VfA paced settings are acceptable.

公开(公告)号：US20190192023A1

公开(公告)日：2019-06-27

申请号：US15853160

申请日：2017-12-22

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh

IPC: A61B5/04 ,  A61B5/0408 ,  A61B5/00 ,  A61N1/365

Abstract: The exemplary systems and methods may be configured for use in the determination of ectopic beat-compensated electrical heterogeneity information. Electrical activity can be monitored by a plurality of external electrodes. Ectopic beat information can be detected. Ectopic beat-compensated electrical heterogeneity information can be generated based on the monitored electrical activity and the detected ectopic beat information.

公开(公告)号：US20190143117A1

公开(公告)日：2019-05-16

申请号：US16186967

申请日：2018-11-12

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh

IPC: A61N1/368 ,  A61N1/365 ,  A61N1/362 ,  A61N1/37

Abstract: An implantable device and associated method for delivering multi-site pacing therapy is disclosed. The device comprises a set of electrodes including a first ventricular electrode and a second ventricular electrode, spatially separated from one another and all coupled to an implantable pulse generator. The device comprises a processor configured for selecting a first cathode and a first anode from the set of electrodes to form a first pacing vector at a first pacing site along a heart chamber and selecting a second cathode and a second anode from the set of electrodes to form a second pacing vector at a second pacing site along the same heart chamber. The pulse generator is configured to deliver first pacing pulses to the first pacing vector and delivering second pacing pulses to the second pacing vector. The pulse generator generates a recharging current for recharging a first coupling capacitor over a first recharge time period in response to the first pacing pulses. The pulse generator for generating a recharging current for recharging a second coupling capacitor over a second recharge time period in response to the second pacing pulses. An order of recharging the first and second coupling capacitors is dependent upon one of ventricular pacing mode, left ventricle to right ventricle delay (V-V) pace delay, multiple point LV delay and latest delivered pacing pulses to one of the first and second pacing vectors.

公开(公告)号：US20190030342A1

公开(公告)日：2019-01-31

申请号：US16152078

申请日：2018-10-04

Applicant: Medtronic, Inc.

Inventor： Richard M.T. Lu ,  Subham Ghosh ,  Robert W. Stadler

IPC: A61N1/37 ,  A61N1/368 ,  A61B5/046 ,  A61N1/362

Abstract: The present disclosure pertains to cardiac pacing methods and systems, and, more particularly, to cardiac resynchronization therapy (CRT). In particular, the present disclosure pertains to determining whether a patient is experiencing atrial fibrillation (AF). If the patient is experiencing AF, the efficacy of CRT is determined. A signal is sensed in response to a ventricular pacing stimulus. Through signal processing, a number of features are parsed from the signal and a determination is made as to whether the ventricular pacing stimulus evoked a response from the ventricle.

公开(公告)号：US10064567B2

公开(公告)日：2018-09-04

申请号：US14227919

申请日：2014-03-27

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh ,  Jeffrey Gillberg ,  Manfred Justen ,  Eric Schilling

IPC: A61N1/365 ,  A61B5/044 ,  A61B5/0205 ,  A61B5/00 ,  A61N1/368 ,  A61N1/37 ,  A61N1/372

CPC classification number: A61B5/044 ,  A61B5/0205 ,  A61B5/4029 ,  A61N1/365 ,  A61N1/36585 ,  A61N1/3686 ,  A61N1/371 ,  A61N1/37247

Abstract: Systems, methods, and graphical user interfaces are described herein for identification of optimal electrical vectors for use in assisting a user in implantation of implantable electrodes to be used in cardiac therapy. Cardiac improvement information may be generated for each pacing configuration, and one or more pacing configuration may be selected based on the cardiac improvement information. Optimal electrical vectors using the selected pacing configurations may be identified using longevity information generated for each electrical vector. Electrodes may then be implanted for use in cardiac therapy to form the optimal electrical vector.