公开(公告)号：US20100106231A1

公开(公告)日：2010-04-29

申请号：US12579036

申请日：2009-10-14

申请人： Nathan A. Torgerson ,  Matthew J. Michaels

发明人： Nathan A. Torgerson ,  Matthew J. Michaels

IPC分类号： A61N1/05

CPC分类号： A61N1/36185 ,  A61N1/36082 ,  A61N1/36125

摘要： A medical electrical stimulator provides selective control of stimulation via a combination of two or more electrodes coupled to respective regulated current paths and one or more electrodes coupled to unregulated current paths. Constant current sources may control the current that is sourced or sunk via respective regulated current paths. An unregulated current path may sink or source current to and from an unregulated voltage source that serves as a reference voltage. Unregulated electrodes may function as unregulated anodes to source current from a reference voltage or unregulated cathodes to sink current to a reference voltage.

摘要翻译： 医疗电刺激器通过耦合到相应的调节电流路径的两个或多个电极和耦合到未调节电流路径的一个或多个电极的组合来提供对刺激的选择性控制。 恒定电流源可以通过相应的调节电流路径控制来源或沉没的电流。 未调节的电流路径可能会吸收或者来自作为参考电压的未调节电压源的电流。 未调节的电极可以用作未调节的阳极，以从参考电压或不调节的阴极源电流以将电流吸收到参考电压。

公开(公告)号：US20100106219A1

公开(公告)日：2010-04-29

申请号：US12579220

申请日：2009-10-14

申请人： Nathan A. Torgerson ,  Matthew J. Michaels ,  Shane A. Self ,  Todd D. Heathershaw

发明人： Nathan A. Torgerson ,  Matthew J. Michaels ,  Shane A. Self ,  Todd D. Heathershaw

IPC分类号： A61N1/36

CPC分类号： A61N1/36082 ,  A61N1/025 ,  A61N1/0531 ,  A61N1/0534 ,  A61N1/08 ,  A61N1/36125 ,  A61N1/36185

摘要： A medical electrical stimulator provides selective control of stimulation via a combination of two or more electrodes coupled to respective regulated current paths and one or more electrodes coupled to unregulated current paths. Constant current sources may control the current that is sourced or sunk via respective regulated current paths. An unregulated current path may sink or source current to and from an unregulated voltage source that serves as a reference voltage. Unregulated electrodes may function as unregulated anodes to source current from a reference voltage or unregulated cathodes to sink current to a reference voltage.

摘要翻译： 医疗电刺激器通过耦合到相应的调节电流路径的两个或多个电极和耦合到未调节电流路径的一个或多个电极的组合来提供对刺激的选择性控制。 恒定电流源可以通过相应的调节电流路径控制来源或沉没的电流。 未调节的电流路径可能会吸收或者来自作为参考电压的未调节电压源的电流。 未调节的电极可以用作未调节的阳极，以从参考电压或不调节的阴极源电流以将电流吸收到参考电压。

公开(公告)号：US20090276010A1

公开(公告)日：2009-11-05

申请号：US12112612

申请日：2008-04-30

申请人： Steven M. Goetz ,  Todd V. Smith ,  Nathan A. Torgerson ,  Warren W. Ball

发明人： Steven M. Goetz ,  Todd V. Smith ,  Nathan A. Torgerson ,  Warren W. Ball

IPC分类号： A61N1/08

CPC分类号： A61N1/08 ,  A61N1/36071 ,  A61N1/36185

摘要： Method, controller and system for an implantable medical device having a plurality of electrodes, the implantable medical device capable of delivering therapeutic stimulation to a patient, comprising a control module, a user interface operatively coupled to the control module, the user interface providing control of the control module by a medical professional or other user, and an electrode interface operatively coupled between the plurality of electrodes and the control module. The control module uses the electrode interface to obtain a plurality of measurements of impedance values for a plurality of selected pairs of individual ones of the plurality of electrodes. The control module flags electrodes using the plurality of measurements of impedance values of the selected pairs of individual ones of the plurality of electrodes comparative to a range, and the delivery of therapy on flagged electrodes is inhibited.

摘要翻译： 用于具有多个电极的可植入医疗装置的方法，控制器和系统，所述可植入医疗装置能够向患者递送治疗刺激，所述可植入医疗装置包括控制模块，可操作地耦合到所述控制模块的用户界面，所述用户界面提供 医疗专业人员或其他用户的控制模块以及可操作地耦合在多个电极和控制模块之间的电极接口。 所述控制模块使用所述电极接口来获得所述多个电极中的多个所选择的对中的多个所选对的多个测量值。 控制模块使用多个电极中所选择的多个电极对的多个阻抗值的测量来标记电极，与一个范围相比较，并且禁止在标记的电极上进行治疗。

公开(公告)号：US20090264956A1

公开(公告)日：2009-10-22

申请号：US12425903

申请日：2009-04-17

申请人： Mark T. Rise ,  Jonathon E. Giftakis ,  Paul H. Stypulkowski ,  Timothy J. Denison ,  Nathan A. Torgerson

发明人： Mark T. Rise ,  Jonathon E. Giftakis ,  Paul H. Stypulkowski ,  Timothy J. Denison ,  Nathan A. Torgerson

IPC分类号： A61N1/36

CPC分类号： A61N1/36082 ,  A61B5/01 ,  A61B5/0488 ,  A61B5/08 ,  A61B5/0816 ,  A61B5/165 ,  A61B5/441 ,  A61B5/4836 ,  A61B5/7275 ,  G06F19/00 ,  G16H20/70 ,  G16H40/63

摘要： A therapy system for managing a psychiatric disorder of the patient may be controlled based on a patient mood state. Therapy may be delivered to a patient according to a therapy program, and a physiological parameter of the patient may be monitored during or after therapy delivery. The patient mood state may be determined based on the monitored physiological parameter, and the therapy delivery may be controlled based on the determined mood state. In some embodiments, the therapy delivery is stopped prior to determining the patient mood state and the therapy delivery is restarted upon detecting a negative mood state. In other embodiments, therapy delivery is delivered until a positive mood state is detected, at which point the therapy delivery may be stopped.

摘要翻译： 可以基于患者情绪状态来控制用于管理患者精神障碍的治疗系统。 治疗可以根据治疗程序递送到患者，并且可以在治疗递送期间或之后监测患者的生理参数。 可以基于所监测的生理参数来确定患者情绪状态，并且可以基于所确定的情绪状态来控制治疗递送。 在一些实施例中，在确定患者情绪状态之前停止治疗递送，并且在检测到负情绪状态时重新开始治疗递送。 在其它实施方案中，递送治疗递送直到检测到正状态，此时可以停止治疗递送。

公开(公告)号：US20080103557A1

公开(公告)日：2008-05-01

申请号：US11590684

申请日：2006-10-31

申请人： Timothy J. Davis ,  Alan Robert Helfinstine ,  Boysie R. Morgan ,  David P. Olson ,  Todd V. Smith ,  Nathan A. Torgerson ,  Leroy L. Perz

发明人： Timothy J. Davis ,  Alan Robert Helfinstine ,  Boysie R. Morgan ,  David P. Olson ,  Todd V. Smith ,  Nathan A. Torgerson ,  Leroy L. Perz

IPC分类号： A61N1/00

CPC分类号： A61N1/3787 ,  A61N2001/37294

摘要： Storable implantable medical device assembly and container for an implantable device having a charging sub-assembly. The implantable medical device has therapeutic componentry and a rechargeable power source operatively coupled to the therapeutic componentry. The charging sub-assembly having an electro-chemical power source, such as a battery, and a charging circuit operatively coupled to the electro-chemical power source. The implantable medical device and the charging sub-assembly are co-located within the container. The charging circuit of the charging sub-assembly is operatively coupled to the chargeable power source within the container to charge the rechargeable power source while the implantable medical device remains in the container. The charging sub-assembly may use inductive coupling to charge the implantable device mimicking implantable device charging following implantation.

摘要翻译： 用于具有充电子组件的可植入装置的可存储的植入式医疗装置组件和容器。 可植入医疗装置具有治疗性组件和可操作地耦合到治疗组件的可再充电电源。 具有诸如电池的电化学电源的充电子组件和可操作地耦合到电化学电源的充电电路。 可植入医疗装置和充电子组件共同位于容器内。 充电子组件的充电电路可操作地耦合到容器内的可充电电源，以在可植入医疗装置保留在容器中时对可再充电电源充电。 充电子组件可以使用电感耦合来对植入后模拟可植入装置充电的可植入装置进行充电。

公开(公告)号：US07089057B2

公开(公告)日：2006-08-08

申请号：US10133925

申请日：2002-04-26

申请人： Todd D. Heathershaw ,  Nathan A. Torgerson ,  Mark Stein

发明人： Todd D. Heathershaw ,  Nathan A. Torgerson ,  Mark Stein

IPC分类号： A61N1/08

CPC分类号： A61N1/36125

摘要： Apparatus and method for monitoring capacitive elements of an implantable medical device system for device failure and responding thereto. A therapy measurement block monitors a charge value across one or more capacitive elements. If the charge value falls outside a prescribed range, indicating possible failure in the capacitive element, the system removes from service the capacitive element and its associated regulator, notifies the implantable neuro stimulator of the failure and/or takes appropriate corrective measures.

公开(公告)号：US06950706B2

公开(公告)日：2005-09-27

申请号：US10133513

申请日：2002-04-26

申请人： John Delfin Rodriguez ,  Nathan A. Torgerson ,  Marc Stein ,  Steven L. Jensen

发明人： John Delfin Rodriguez ,  Nathan A. Torgerson ,  Marc Stein ,  Steven L. Jensen

IPC分类号： A61N1/34 ,  A61N1/36 ,  A61N1/372 ,  A61N1/00

CPC分类号： A61N1/36071

摘要： In the embodiment of the invention, apparatus and method provide flexibility in generating a stimulation waveform (that comprises at least a stimulation pulse) to an electrode of an Implantable Neuro Stimulator (INS). The waveform is synthesized for each rate period interval. A portion of the rate period interval is identified, in which the portion comprises at least one phase. During each phase, the stimulation waveform is synthesized by a waveform controller and a waveform generator. The waveform controller utilizes waveform parameters, e.g. the initial value, final value, and step time duration, to form a digital signal to the waveform generator. The waveform generator utilizes the digital signal to form the synthesized waveform.

摘要翻译： 在本发明的实施例中，装置和方法提供了向植入式神经刺激器（INS）的电极生成刺激波形（至少包括刺激脉冲）的灵活性。 每个速率周期间隔合成波形。 识别速率周期间隔的一部分，其中该部分包括至少一个相位。 在每个阶段，刺激波形由波形控制器和波形发生器合成。 波形控制器利用波形参数，例如 初始值，最终值和步长持续时间，以形成到波形发生器的数字信号。 波形发生器利用数字信号形成合成波形。

公开(公告)号：US10543359B2

公开(公告)日：2020-01-28

申请号：US12432268

申请日：2009-04-29

申请人： Jonathon E. Giftakis ,  Nathan A. Torgerson

发明人： Jonathon E. Giftakis ,  Nathan A. Torgerson

IPC分类号： A61B5/0476 ,  A61N1/05 ,  A61B5/03 ,  A61B5/00 ,  A61N1/36

摘要： A medical system implements a seizure detection algorithm to detect a seizure based on a first patient parameter. The medical system monitors a second patient parameter to adjust the seizure detection algorithm. In some examples, the medical system determines whether a seizure for which therapy delivery is desirable occurred based on a second patient parameter. If a target seizure occurred, and the seizure detection algorithm did not detect the target seizure, the medical system adjusts the seizure detection algorithm to detect the target seizure. For example, the medical system may determine a first patient parameter characteristic indicative of the target seizure detected based on the second patient parameter and store the first patient parameter characteristic as part of the seizure detection algorithm. In some examples, the first patient parameter is an electrical brain signal and the second patient parameter is patient activity (e.g., patient motion or posture).

公开(公告)号：US09987493B2

公开(公告)日：2018-06-05

申请号：US12579036

申请日：2009-10-14

申请人： Nathan A. Torgerson ,  Matthew J. Michaels

发明人： Nathan A. Torgerson ,  Matthew J. Michaels

IPC分类号： A61N1/36

CPC分类号： A61N1/36185 ,  A61N1/36082 ,  A61N1/36125

摘要： A medical electrical stimulator provides selective control of stimulation via a combination of two or more electrodes coupled to respective regulated current paths and one or more electrodes coupled to unregulated current paths. Constant current sources may control the current that is sourced or sunk via respective regulated current paths. An unregulated current path may sink or source current to and from an unregulated voltage source that serves as a reference voltage. Unregulated electrodes may function as unregulated anodes to source current from a reference voltage or unregulated cathodes to sink current to a reference voltage.

公开(公告)号：US09937342B2

公开(公告)日：2018-04-10

申请号：US12110906

申请日：2008-04-28

申请人： Dennis M. Skelton ,  Joseph J. Nolan ,  Nathan A. Torgerson ,  Wende L. Dewing ,  Todd V. Smith ,  Shyam Gokaldas ,  Steven M. Goetz ,  Andrew H. Houchins ,  Jeffrey T. Keacher

发明人： Dennis M. Skelton ,  Joseph J. Nolan ,  Nathan A. Torgerson ,  Wende L. Dewing ,  Todd V. Smith ,  Shyam Gokaldas ,  Steven M. Goetz ,  Andrew H. Houchins ,  Jeffrey T. Keacher

IPC分类号： A61N1/05 ,  A61N1/372

CPC分类号： A61N1/0553 ,  A61N1/0531 ,  A61N1/0534 ,  A61N1/37247

摘要： The disclosure provides techniques for parameter-directed shifting of electrical stimulation electrode combinations. An external programmer permits a user to shift electrode combinations, e.g., along the length of a lead or leads. The external programmer accepts shift input and causes an electrical stimulator to shift electrode combinations as indicated by the input. Different sets of electrodes may have different electrode counts. For example, an array of electrodes carried by one lead may have a greater number of electrodes than an array of electrodes carried on another lead. The disclosure provides techniques for shifting electrode combinations among leads with different electrode counts. For example, an external programmer may execute shifts in a series of shift operations, where the number of shift operations along the length of a lead having a greater electrode count is greater than the number of shift steps along the length of a lead having a lesser electrode count.