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公开(公告)号：US20080125702A1
公开(公告)日：2008-05-29
申请号：US12021967
申请日：2008-01-29
IPC分类号： A61M5/142
CPC分类号： A61M5/14276 , A61M5/1452 , A61M5/16881 , A61M2005/14264 , A61M2005/14506 , A61M2205/33 , A61M2205/3372
摘要： The present invention relates to an implantable infusion pump having a refillable infusate reservoir in fluid communication with a delivery site via a flow path. This flow path includes a flow resistance. The infusion pump includes a sensing device(s), positioned relative to the flow path, to provide data regarding a flow rate along the flow path. The infusion pump effects a division of a total flow period into at least a plurality of unit dose periods, each unit dose period effecting delivery of a unit dose of infusate. The cumulative effect of delivering the total number of unit dose periods is the delivery of a desired dose over the total flow period. The present invention permits a reservoir pressure to vary over any portion of total flow period but effects a constant-pressure state over each unit dose cycle.
摘要翻译： 本发明涉及一种植入式输注泵，其具有经由流路与输送部位流体连通的可再填充输液管储存器。 该流路包括流动阻力。 输液泵包括相对于流动路径定位的感测装置，以提供关于沿着流动路径的流量的数据。 输注泵将总流动周期分成至少多个单位剂量周期，每个单位剂量周期影响输送单位剂量的输注液。 递送单位剂量周期总数的累积效应是在总流动周期内递送期望的剂量。 本发明允许储存器压力在总流动周期的任何部分上变化，但是在每个单位剂量周期上影响恒定压力状态。
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公开(公告)号：US07295876B1
公开(公告)日：2007-11-13
申请号：US11072998
申请日：2005-03-04
申请人： John H. Erickson
发明人： John H. Erickson
IPC分类号： A61N1/18
CPC分类号： A61N1/08
摘要： A system, method, and computer program product for interactively defining and calibrating a treatment protocol program for a stimulation device such as an implantable pulse generator (IPG). An IPG, whether it is a self-contained implantable pulse generator (SCIPG) or externally-powered implantable pulse generator (EPIPG), communicates with an external patient programmer (EPP) to receive treatment protocol programs. Using the EPP, treatment protocol programs are developed, executed, and tested while the patient provides real-time feedback, providing efficient and effective programming.
摘要翻译： 一种用于交互地定义和校准诸如可植入脉冲发生器（IPG）的刺激装置的治疗协议程序的系统，方法和计算机程序产品。 IPG，无论是独立的可植入脉冲发生器（SCIPG）还是外部供电的可植入脉冲发生器（EPIPG），与外部患者编程器（EPP）通信以接收治疗协议程序。 使用EPP，开发，执行和测试治疗方案程序，同时患者提供实时反馈，提供高效和有效的编程。
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公开(公告)号：US06880564B2
公开(公告)日：2005-04-19
申请号：US10331425
申请日：2002-12-30
申请人： John H. Erickson
发明人： John H. Erickson
CPC分类号： A61M5/14276 , A61M5/14216 , A61M5/16881 , A61M39/22 , A61M2005/14208 , A61M2205/3507 , F04B49/225 , Y10T137/0318 , Y10T137/8242 , Y10T137/86389 , Y10T137/88062
摘要： The invention is directed to a dose control apparatus. The apparatus has two armatures pressed against a valve seat by at least one spring. A coil induces a magnetic field that motivates the armatures against the force of the spring, thereby opening the valve. The armatures may move along a common axis in opposite directions. The apparatus may also include a core located between the armatures and a casing about the coil. The core and casing act to guide the magnetic field, reducing the power requirements for creating the field. Current may be periodically reversed in the coil to provide a degaussing field. In addition, a signal may be produced by the coil in the presence an externally applied magnetic field such as an MRI. An opposing magnetic field may be produced by the coil or the current provided to the coil may be adjusted.
摘要翻译： 本发明涉及剂量控制装置。 该装置具有通过至少一个弹簧压靠在阀座上的两个电枢。 线圈引起磁场，其抵抗弹簧的力促使电枢，从而打开阀。 电枢可以沿着相反方向的公共轴线移动。 该装置还可以包括位于电枢之间的芯和围绕线圈的外壳。 核心和套管用于引导磁场，减少了创建场地的功率要求。 线圈中的电流可以周期性地反转以提供消磁场。 此外，在存在诸如MRI的外部施加的磁场的情况下，可以由线圈产生信号。 可以通过线圈产生相反的磁场，或者可以调节提供给线圈的电流。
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公开(公告)号：US08838243B2
公开(公告)日：2014-09-16
申请号：US13471153
申请日：2012-05-14
CPC分类号： A61N1/36192 , A61N1/08 , A61N1/36071 , A61N1/37241 , A61N1/37247 , A61N1/37264 , A61N1/3758 , A61N1/3787 , G16H40/63
摘要： In one embodiment, a method of programming an IPG comprises providing one or several GUI screens on the programmer device, the GUI screens comprising a master amplitude GUI control for controlling amplitudes for stimsets of a stimulation program and one or several balancing GUI controls for controlling amplitudes of each stimset of the stimulation program; communicating one or several commands from the programmer device to the IPG to change the amplitude of all stimsets of the stimulation program in response to manipulation of the master amplitude GUI control, wherein the amplitude of each stimulation set is automatically calculated by a level selected through the master amplitude GUI control and one or several calibration parameters for the respective stimulation set; and automatically recalculating the one or several calibration parameters for a respective stimulation set in response to manipulation of one of the balancing GUI controls and storing the recalculated calibration parameters.
摘要翻译： 在一个实施例中，编程IPG的方法包括在编程器设备上提供一个或多个GUI屏幕，GUI屏幕包括用于控制刺激程序的刺激的幅度的主幅度GUI控制和用于控制幅度的一个或多个平衡GUI控件 刺激计划的每个刺激; 将一个或多个命令从编程器设备传送到IPG，以响应于主幅度GUI控制的操纵来改变刺激程序的所有刺激的幅度，其中每个刺激集合的幅度被自动计算通过 主幅度GUI控制和用于各个刺激组的一个或几个校准参数; 以及响应于所述平衡GUI控件之一的操纵并且存储所述重新计算的校准参数而自动重新计算相应刺激组的所述一个或多个校准参数。
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公开(公告)号：US08180451B2
公开(公告)日：2012-05-15
申请号：US12814968
申请日：2010-06-14
IPC分类号： A61N1/08
CPC分类号： A61N1/36192 , A61N1/08 , A61N1/36071 , A61N1/37241 , A61N1/37247 , A61N1/37264 , A61N1/3758 , A61N1/3787 , G16H40/63
摘要： In one embodiment, a method of programming an IPG comprises providing one or several GUI screens on the programmer device, the GUI screens comprising a master amplitude GUI control for controlling amplitudes for stimsets of a stimulation program and one or several balancing GUI controls for controlling amplitudes of each stimset of the stimulation program; communicating one or several commands from the programmer device to the IPG to change the amplitude of all stimsets of the stimulation program in response to manipulation of the master amplitude GUI control, wherein the amplitude of each stimulation set is automatically calculated by a level selected through the master amplitude GUI control and one or several calibration parameters for the respective stimulation set; and automatically recalculating the one or several calibration parameters for a respective stimulation set in response to manipulation of one of the balancing GUI controls and storing the recalculated calibration parameters.
摘要翻译： 在一个实施例中，编程IPG的方法包括在编程器设备上提供一个或多个GUI屏幕，GUI屏幕包括用于控制刺激程序的刺激的幅度的主幅度GUI控制和用于控制幅度的一个或多个平衡GUI控件 刺激计划的每个刺激; 将一个或多个命令从编程器设备传送到IPG，以响应于主幅度GUI控制的操纵来改变刺激程序的所有刺激的幅度，其中每个刺激集合的幅度被自动计算通过 主幅度GUI控制和用于各个刺激组的一个或几个校准参数; 以及响应于所述平衡GUI控件之一的操纵并且存储所述重新计算的校准参数而自动重新计算相应刺激组的所述一个或多个校准参数。
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56.发明授权公开(公告)号：US07981119B2
公开(公告)日：2011-07-19
申请号：US11010136
申请日：2004-12-10
IPC分类号： A61B19/00
CPC分类号： A61N1/0539 , A61N1/36017 , A61N1/36067
摘要： In one aspect, an apparatus is provided for securing an electrical stimulation lead in position in a person's brain. The apparatus includes a flexible disc comprising a substantially radial slot adapted to secure the lead in position within the brain after implantation. The slot is adapted to elastically expand as the lead is inserted into the slot and is also adapted to elastically contract on the lead to secure the lead in position within the brain after implantation. The apparatus further includes a ring adapted to seat within a burr hole formed in the person's skull. The ring comprises a channel adapted to receive and secure the flexible disc.
摘要翻译： 一方面，提供一种用于将电刺激引线固定在人的大脑中的位置的装置。 该装置包括柔性盘，其包括适于在植入之后将引线固定在大脑内部的位置的基本上径向的槽。 插槽适于在引线插入槽中时弹性膨胀，并且还适于在植入之后弹性收缩引线以将引线固定在大脑内的适当位置。 该装置还包括适于位于形成在人的头骨中的钻孔内的环。 环包括适于接收和固定软盘的通道。
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公开(公告)号：US07896018B2
公开(公告)日：2011-03-01
申请号：US12559232
申请日：2009-09-14
申请人： John H. Erickson
发明人： John H. Erickson
CPC分类号： A61M5/14276 , A61M5/14216 , A61M5/16881 , A61M39/22 , A61M2005/14208 , A61M2205/3507 , F04B49/225 , Y10T137/0318 , Y10T137/8242 , Y10T137/86389 , Y10T137/88062
摘要： The invention is directed to a dose control apparatus. The apparatus has two armatures pressed against a valve seat by at least one spring. A coil induces a magnetic field that motivates the armatures against the force of the spring, thereby opening the valve. The armatures may move along a common axis in opposite directions. The apparatus may also include a core located between the armatures and a casing about the coil. The core and casing act to guide the magnetic field, reducing the power requirements for creating the field. Current may be periodically reversed in the coil to provide a degaussing field. In addition, a signal may be produced by the coil in the presence an externally applied magnetic field such as an MRI. An opposing magnetic field may be produced by the coil or the current provided to the coil may be adjusted.
摘要翻译： 本发明涉及剂量控制装置。 该装置具有通过至少一个弹簧压靠在阀座上的两个电枢。 线圈引起磁场，其抵抗弹簧的力促使电枢，从而打开阀。 电枢可以沿着相反方向的公共轴线移动。 该装置还可以包括位于电枢之间的芯和围绕线圈的外壳。 核心和套管用于引导磁场，减少了创建场地的功率要求。 线圈中的电流可以周期性地反转以提供消磁场。 此外，在存在诸如MRI的外部施加的磁场的情况下，可以由线圈产生信号。 可以通过线圈产生相反的磁场，或者可以调节提供给线圈的电流。
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公开(公告)号：US07738963B2
公开(公告)日：2010-06-15
申请号：US11359746
申请日：2006-02-21
CPC分类号： A61N1/36192 , A61N1/08 , A61N1/36071 , A61N1/37241 , A61N1/37247 , A61N1/37264 , A61N1/3758 , A61N1/3787 , G16H40/63
摘要： In one embodiment, a method of programming an IPG comprises providing one or several GUI screens on the programmer device, the GUI screens comprising a master amplitude GUI control for controlling amplitudes for stimsets of a stimulation program and one or several balancing GUI controls for controlling amplitudes of each stimset of the stimulation program; communicating one or several commands from the programmer device to the IPG to change the amplitude of all stimsets of the stimulation program in response to manipulation of the master amplitude GUI control, wherein the amplitude of each stimulation set is automatically calculated by a level selected through the master amplitude GUI control and one or several calibration parameters for the respective stimulation set; and automatically recalculating the one or several calibration parameters for a respective stimulation set in response to manipulation of one of the balancing GUI controls and storing the recalculated calibration parameters.
摘要翻译： 在一个实施例中，编程IPG的方法包括在编程器设备上提供一个或多个GUI屏幕，GUI屏幕包括用于控制刺激程序的刺激的幅度的主幅度GUI控制和用于控制幅度的一个或多个平衡GUI控件 刺激计划的每个刺激; 将一个或多个命令从编程器设备传送到IPG，以响应于主幅度GUI控制的操纵来改变刺激程序的所有刺激的幅度，其中每个刺激集合的幅度被自动计算通过 主幅度GUI控制和用于各个刺激组的一个或几个校准参数; 以及响应于所述平衡GUI控件之一的操纵并且存储所述重新计算的校准参数而自动重新计算相应刺激组的所述一个或多个校准参数。
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公开(公告)号：US20100010479A1
公开(公告)日：2010-01-14
申请号：US12559232
申请日：2009-09-14
申请人： John H. Erickson
发明人： John H. Erickson
IPC分类号： A61K9/22
CPC分类号： A61M5/14276 , A61M5/14216 , A61M5/16881 , A61M39/22 , A61M2005/14208 , A61M2205/3507 , F04B49/225 , Y10T137/0318 , Y10T137/8242 , Y10T137/86389 , Y10T137/88062
摘要： The invention is directed to a dose control apparatus. The apparatus has two armatures pressed against a valve seat by at least one spring. A coil induces a magnetic field that motivates the armatures against the force of the spring, thereby opening the valve. The armatures may move along a common axis in opposite directions. The apparatus may also include a core located between the armatures and a casing about the coil. The core and casing act to guide the magnetic field, reducing the power requirements for creating the field. Current may be periodically reversed in the coil to provide a degaussing field. In addition, a signal may be produced by the coil in the presence an externally applied magnetic field such as an MRI. An opposing magnetic field may be produced by the coil or the current provided to the coil may be adjusted.
摘要翻译： 本发明涉及剂量控制装置。 该装置具有通过至少一个弹簧压靠在阀座上的两个电枢。 线圈引起磁场，其抵抗弹簧的力促使电枢，从而打开阀。 电枢可以沿着相反方向的公共轴线移动。 该装置还可以包括位于电枢之间的芯和围绕线圈的外壳。 核心和套管用于引导磁场，减少了创建场地的功率要求。 线圈中的电流可以周期性地反转以提供消磁场。 此外，在存在诸如MRI的外部施加的磁场的情况下，可以由线圈产生信号。 可以通过线圈产生相反的磁场，或者可以调节提供给线圈的电流。
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公开(公告)号：US07588046B1
公开(公告)日：2009-09-15
申请号：US11065726
申请日：2005-02-25
申请人： John H. Erickson
发明人： John H. Erickson
IPC分类号： F16K31/06
CPC分类号： A61M5/14276 , A61M5/14216 , A61M5/16881 , A61M39/22 , A61M2005/14208 , A61M2205/3507 , F04B49/225 , Y10T137/0318 , Y10T137/8242 , Y10T137/86389 , Y10T137/88062
摘要： The invention is directed to a dose control apparatus. The apparatus has two armatures pressed against a valve seat by at least one spring. A coil induces a magnetic field that motivates the armatures against the force of the spring, thereby opening the valve. The armatures may move along a common axis in opposite directions. The apparatus may also include a core located between the armatures and a casing about the coil. The core and casing act to guide the magnetic field, reducing the power requirements for creating the field. Current may be periodically reversed in the coil to provide a degaussing field. In addition, a signal may be produced by the coil in the presence an externally applied magnetic field such as an MRI. An opposing magnetic field may be produced by the coil or the current provided to the coil may be adjusted.
摘要翻译： 本发明涉及剂量控制装置。 该装置具有通过至少一个弹簧压靠在阀座上的两个电枢。 线圈引起磁场，其抵抗弹簧的力促使电枢，从而打开阀。 电枢可以沿着相反方向的公共轴线移动。 该装置还可以包括位于电枢之间的芯和围绕线圈的外壳。 核心和套管用于引导磁场，减少了创建场地的功率要求。 线圈中的电流可以周期性地反转以提供消磁场。 此外，在存在诸如MRI的外部施加的磁场的情况下，可以由线圈产生信号。 可以通过线圈产生相反的磁场，或者可以调节提供给线圈的电流。
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