公开(公告)号：US6411093B2

公开(公告)日：2002-06-25

申请号：US78040601

申请日：2001-02-12

申请人： BRUKER BIOSPIN AG

发明人： SCHWILCH ARTHUR ,  GOSTELI CHRISTOPH

IPC分类号： G01R33/36 ,  H03B28/00 ,  G01V3/00

CPC分类号： G01R33/3607

摘要： A method of operating a high-resolution NMR spectrometer comprising a DDS generator containing an NCOL for generating an LO frequency, wherein the frequency of the NCOL is defined by inputting a numerical value Z, is characterized in that this numerical value Z may assume only values which satisfy the equation Z=n.N/m, wherein Z, n, N, and m are integer and positive numbers, N is a power of 2 with a positive integer exponent, wherein said exponent represents the maximum number of bits during the calculation process, m is approximately 2.fs/DELTAB, n approximately m.fout/fs and m additionally a common integer divisor of n.N and fs is the clock frequency of the NCOL, DELTAB is the desired bandwidth with high spectral purity and fout is the output frequency of the NCOL. This method allows the use of a DDS generator even in the case where very high spectral purity is required, wherein in particular quantization noise is largely eliminated over the frequency range relevant for NMR measurements.

摘要翻译： 一种操作包括含有用于产生LO频率的NCOL的DDS发生器的高分辨率NMR光谱仪的方法，其中通过输入数值Z来定义NCOL的频率，其特征在于该数值Z可以仅取值 其满足方程Z = nN / m，其中Z，n，N和m是整数和正数，N是具有正整数指数的2的幂，其中所述指数表示在计算过程期间的最大比特数 ，m约为2.fs / DELTAB，n约为m.fout / fs，m为nN的公共整数除数，fs为NCOL的时钟频率，DELTAB为高频谱纯度的期望带宽，fout为输出 NCOL的频率。 即使在需要非常高的光谱纯度的情况下，该方法也允许使用DDS发生器，其中在与NMR测量相关的频率范围内，特别是消除了量化噪声。

公开(公告)号：US11199599B2

公开(公告)日：2021-12-14

申请号：US15841947

申请日：2017-12-14

申请人： Bruker BioSpin AG

发明人： Kenneth Guenter ,  Robert Schauwecker

IPC分类号： G01R33/3815 ,  G01R33/385 ,  H01B1/02 ,  H01F6/06 ,  G01R33/3875 ,  H01H3/00

摘要： A magnet assembly in a magnetic resonance apparatus includes a cryostat and a superconducting main field magnet coil system arranged therein for generating a magnetic field in the direction of a z-axis in a working volume. The magnet assembly includes a shim device arranged inside the cryostat for adjusting the spatial variation or homogeneity of the magnetic field generated in the working volume by the magnet coil system. The shim device comprises at least one closed superconducting shim conductor path having an HTS layer. The HTS layer forms a surface that is geometrically developable such that unwrapping onto a plane changes the geodesic distance between any two points on the surface formed by the HTS layer by no more than 10%. The inner and/or outer contour of the geometrical development of the HTS layer describes a non-convex curve.

公开(公告)号：US10830845B2

公开(公告)日：2020-11-10

申请号：US16194907

申请日：2018-11-19

申请人： Bruker BioSpin AG

发明人： Jevgeni Guidoulianov ,  Nicolas Freytag

IPC分类号： G01R33/30 ,  G01R33/46

摘要： A first radial bearing includes nozzles in the stator at a radius r1 and a bearing surface on a circular section of the rotor at a radius R1. A second radial bearing includes nozzles in the stator at a radius r2 and a bearing surface on the rotor at a radius R2. An axial bearing includes a nozzle in the stator and a bearing surface on an axial end of the rotor, which runs orthogonally to the rotation axis and has an outer radius R3. The second radial bearing is formed on an end section of the rotor, which has a smaller radius than or a radius that decreases away from the circular section, so that R2

公开(公告)号：US10649047B2

公开(公告)日：2020-05-12

申请号：US16194900

申请日：2018-11-19

申请人： Bruker BioSpin AG

发明人： Nicolas Freytag ,  Fabian Kuehler ,  David Osen

IPC分类号： G01R33/30 ,  G01R33/34

摘要： An MAS NMR probe head arrangement has a stator (2) aligned along an axis of rotation (RA) to support a rotor (1), a stator mount (32), and a RF coil arrangement (21) to emit/receive RF pulses into/from the measurement substance (40) in the rotor. The stator mount has a stator bearing (41) into which the stator can be axially inserted and extracted. The stator, when inserted, passes through the RF coil arrangement (21), and can be fed through the RF coil arrangement (21). A mechanism fixes the stator axially in the stator bearing (41) when inserted. This arrangement enhances both ease of assembly and maintenance of the arrangement.

公开(公告)号：US10557899B2

公开(公告)日：2020-02-11

申请号：US16026552

申请日：2018-07-03

申请人： Bruker BioSpin AG

发明人： Roger Meister ,  Daniel Guy Baumann ,  Daniel Schmidig ,  Christian Kasper

IPC分类号： G01R33/36 ,  H01G4/38 ,  G01R33/34

摘要： An adjustment device (1) for an RF resonant circuit (96) of an NMR probe (90) has a plurality of movable elements (6) which are arranged in succession, such that adjacent movable elements mutually engage, so as to be movable relative to one another in a limited range. The movable elements each have at least one electrical functional part (20; 20a-20b) for adjusting the RF resonant circuit. N outwardly oriented electrical contact elements (15; 15a-15b; 23, 24) include at least two functional part terminals (21, 22), and the electrical contact elements are each connected to a functional part terminal. The adjustment device also includes a first connection assembly (11) for slidingly contacting at least a portion of the movable elements from outside, to contact the contact elements in dependence on the movement position of the movable elements, as well as a movement device (4), configured to move one of the movable elements.

公开(公告)号：US10401447B2

公开(公告)日：2019-09-03

申请号：US15487089

申请日：2017-04-13

申请人： Bruker BioSpin AG

发明人： Patrick Wikus ,  Steffen Bonn

IPC分类号： G01V3/00 ,  G01R33/38 ,  F25B9/14 ,  F25D19/00 ,  G01R33/3815

摘要： A cooling device (1) has a cryostat (2) and a cold head (3) of a cooling system (52), and additionally includes a pivot bearing (35), with which the cold head (3) is mounted on the cryostat (2) so as to be rotatable about a rotation axis (A). A connecting line (15) for a working gas of the cooling system (52) is connected to the cold head so that forces caused by the cooling system (52) act on the cold head (3) via the connecting line (15) at a force application point (EP) in a force application direction (ER). The force application direction (ER) is inclined by no more than 40° with respect to the normal (N) of a lever plane (HE) which contains the rotation axis (A) and the force application point (EP).

公开(公告)号：US10310034B2

公开(公告)日：2019-06-04

申请号：US15091592

申请日：2016-04-06

申请人： Bruker BioSpin AG

发明人： Nicolas Freytag

IPC分类号： G01R33/36 ,  G01R33/343 ,  G01R33/34 ,  G01R33/422 ,  G01R33/565

摘要： A nuclear magnetic resonance coil configuration having at least one flat or cylindrical coil (18), through which current flows in operation, which coil generates a high-frequency magnetic B1 field at the location of a sample (16) which is oriented parallel to an x-axis, and which for the purpose of connection to a tuning network is connected to at least two electrical feed lines (11), through which in-phase currents flow in operation, and which generate a high-frequency magnetic B2 field in the sample (16), the orientation of which encloses an angle α with the direction of the B1 field, is characterized in that the following applies for the angle α: α=180°±Δα, where Δα

公开(公告)号：US20190108932A1

公开(公告)日：2019-04-11

申请号：US16155262

申请日：2018-10-09

申请人： Bruker BioSpin AG

发明人： Patrick WIKUS ,  Joerg HINDERER ,  Marco STROBEL

IPC分类号： H01F6/06 ,  H01F6/04

摘要： A magnet assembly (1) with a cryostat (2) has a superconducting magnet coil system (3), an active cooling device (4) for the coil system, and current leads (5a, 5b) for charging the coil system. The current leads have at least one normal-conducting region (15a, 15b), wherein multiple cold reservoirs (20) are thermally coupled to the current leads along the normal-conducting region thereof, in order to absorb heat the normal-conducting region during charging of the magnet coil system. The current leads have a variable cross-sectional area B in the normal-conducting region along the extension direction thereof, wherein at least over a predominant fraction of their overall length in the normal-conducting region, the cross-sectional area B decreases from a cold end (18a, 18b) toward a warm end (19a, 19b). This provides a magnet assembly requiring reduced cooling power during charging, with less heat introduced into the magnet coil system in normal operation.

公开(公告)号：US10228430B2

公开(公告)日：2019-03-12

申请号：US14296476

申请日：2014-06-05

申请人： BRUKER BIOSPIN AG

发明人： Marc A. Schnell ,  Marc Enrique Paredes ,  Cengiz Cetrefli ,  Philippe Stauffenegger ,  Daniel Marek

IPC分类号： G01R33/34 ,  G01R33/31

摘要： A method for the transmission/reception of RF signals for NMR measurements uses a heat exchanger (1) for cooling heat sources (5), the heat exchanger having a contact element (4.2) for thermal connection between a cryogenic fluid and the heat source, is characterized in that the heat exchanger comprises a container having an interior volume VB into which a first cryogenic fluid F1 that has a liquid component F1L and a gaseous component F1G flows through an inflow conduit (8) and from which a second cryogenic fluid F2 that has liquid component F2L and a gaseous component F2G flows out through an outflow conduit (9). The inflow conduit has a flow cross-section QZ and a circumference UZ from which an associated parameter VZ=4·Q2Z/UZ results, wherein VB>10·VZ, and the outflow conduit has a flow diameter QA wherein QA≥QZ. The contact element is in close thermal contact with both the liquid volume component VL of the cryogenic fluid and with the heat source. A device for setting the inflow quantity of the first cryogenic fluid F1 into the container is provided that ensures a state F1L/F1G>F2L/F2G during operation. In this way, vibrations due to the cooling process can be largely reduced and the consumption of cryogenic fluid minimized.

公开(公告)号：US10203381B2

公开(公告)日：2019-02-12

申请号：US15988508

申请日：2018-05-24

申请人： Bruker BioSpin AG

发明人： Roger Meister ,  Daniel Schmidig

IPC分类号： G01R33/36 ,  G01R33/34 ,  G01R33/30

摘要： An NMR probe head (1) comprising one or more HF coils (2) arranged around a vertical axis of symmetry (z), and an HF network (3) surrounded by an apparatus (4) for shielding from external HF radiation comprising an electrically conductive shielding tube (5) arranged along a z-axis and that can be moved around the HF coils and the HF network in a z direction towards a base disc (6)A shielding disc (7) is provided at an axial distance from the base disc, wherein a tensible HF seal (8) is arranged between the shielding disc and the shielding tube. When the shielding tube is in a mounted state, the HF seal, in a first mounting state, can slide over the shielding disc in an unbraced and force-free manner. When the HF seal is in a second mounting state, the HF seal is mechanically braced between the shielding disc and the shielding tube to ensure an electrically conductive connection.