公开(公告)号：US20130197233A1

公开(公告)日：2013-08-01

申请号：US13638310

申请日：2011-03-29

Applicant: Anu Mittal ,  Anmol Kumar Ray ,  Mahavir Singh Khanna ,  Rajesh Kumar Thaper ,  Mohan Prasad

Inventor： Anu Mittal ,  Anmol Kumar Ray ,  Mahavir Singh Khanna ,  Rajesh Kumar Thaper ,  Mohan Prasad

IPC: C07D401/12

CPC classification number: C07D401/12

Abstract: The present invention relates to the salts of dexlansoprazole in amorphous form. The present invention further relates to processes for the preparation of salts of dexlansoprazole.

Abstract translation: 本发明涉及无定形形式的右兰索拉唑盐。 本发明还涉及右兰索拉唑盐的制备方法。

公开(公告)号：US20130005777A1

公开(公告)日：2013-01-03

申请号：US13508878

申请日：2010-11-12

Applicant: Jagdev Singh Jaryal ,  Swargam Sathyanarayana ,  Rajesh Kumar Thaper ,  Mohan Prasad

Inventor： Jagdev Singh Jaryal ,  Swargam Sathyanarayana ,  Rajesh Kumar Thaper ,  Mohan Prasad

IPC: C07D213/81 ,  A61K31/44

CPC classification number: C07D213/81

Abstract: The present invention provides sorafenib ethane sulphonate, process for its preparation, pharmaceutical composition comprising sorafenib ethane sulphonate and its use for the treatment of cancer. Formula (III).

Abstract translation: 本发明提供索拉非尼乙磺酸盐，其制备方法，包含索拉非尼乙磺酸盐的药物组合物及其用于治疗癌症的用途。 式（III）。

公开(公告)号：US20120184750A1

公开(公告)日：2012-07-19

申请号：US13321231

申请日：2010-05-20

Applicant: Ashwini Kumar Kapoor ,  Hiten Sharadchandra Mehta ,  Asok Nath ,  Mohan Prasad

Inventor： Ashwini Kumar Kapoor ,  Hiten Sharadchandra Mehta ,  Asok Nath ,  Mohan Prasad

IPC: C07D405/14

CPC classification number: C07D405/14

Abstract: The present invention provides an improved process for the preparation of olmesartan medoxomil, which is free of OLM-acid and has lower amount of eliminate and acetic acid impurity.

Abstract translation: 本发明提供了一种制备奥美沙坦酯的改进方法，其不含OLM-酸并具有较少量的消除和乙酸杂质。

公开(公告)号：US20120070470A1

公开(公告)日：2012-03-22

申请号：US13240795

申请日：2011-09-22

Applicant: Mohan Prasad Pahari ,  Giacomo Basadonna ,  Denny Lo

Inventor： Mohan Prasad Pahari ,  Giacomo Basadonna ,  Denny Lo

IPC: A61K9/14 ,  A61M5/00 ,  A61M37/00 ,  A61K33/06 ,  A61P7/04 ,  B82Y5/00

CPC classification number: A61K33/06 ,  A61F13/00034 ,  A61F13/00063 ,  A61F13/36 ,  A61F2013/00472 ,  A61K8/0208 ,  A61K9/14 ,  A61L15/28 ,  A61L15/44 ,  A61L15/60 ,  A61L26/0004 ,  A61L26/0066 ,  A61L26/0076 ,  A61L2300/404 ,  A61L2400/04 ,  A61M11/007 ,  A61M35/003 ,  A61M2202/064

Abstract: Compositions that include a clay such as kaolin dispersed in a liquid such as water may be useful for promoting the clotting of blood. The compositions may be in a liquid, gel, paste, foam, or another form. Uses may include treating a traumatic injury such as in injury caused by a bullet, an explosive, a blade etc., or an injury caused during a medical procedure such as surgery.

Abstract translation: 包括分散在诸如水的液体中的粘土如高岭土的组合物可用于促进血液凝固。 组合物可以是液体，凝胶，糊剂，泡沫或其它形式。 用途可以包括治疗创伤性损伤，例如由子弹，爆炸物，刀片等引起的损伤，或在诸如手术的医疗过程中引起的损伤。

公开(公告)号：US20110207933A1

公开(公告)日：2011-08-25

申请号：US13100833

申请日：2011-05-04

Applicant: Yatendra KUMAR ,  Mohan PRASAD ,  Mahivir Singh KHANNA ,  Seema AHUJA

Inventor： Yatendra KUMAR ,  Mohan PRASAD ,  Mahivir Singh KHANNA ,  Seema AHUJA

IPC: C07D413/14

CPC classification number: C07D417/12

Abstract: The invention relates to processes for the preparation of substantially pure ziprasidone. The invention also relates to the preparation of acid addition salts of ziprasidone. More particularly, it relates to the preparation of substantially pure hydrochloride salt of ziprasidone. The invention also relates to pharmaceutical compositions that include the substantially pure ziprasidone or ziprasidone hydrochloride and use of said compositions for treating schizophrenia.

Abstract translation: 本发明涉及制备基本上纯的齐拉西酮的方法。 本发明还涉及齐拉西酮的酸加成盐的制备。 更具体地说，本发明涉及齐拉西酮基本上纯的盐酸盐的制备。 本发明还涉及药物组合物，其包括基本上纯的齐拉西酮或齐拉昔酮盐酸盐以及所述组合物用于治疗精神分裂症的用途。

公开(公告)号：US20110082293A1

公开(公告)日：2011-04-07

申请号：US12934348

申请日：2009-03-23

Applicant: Vinod George ,  Hashim Nizar Poovanathil Nagoor Meeran ,  Neera Tiwari ,  Mohan Prasad

Inventor： Vinod George ,  Hashim Nizar Poovanathil Nagoor Meeran ,  Neera Tiwari ,  Mohan Prasad

IPC: C07D487/04

CPC classification number: C07D477/20

Abstract: The present invention relates to a process for the preparation of sterile doripenem.

Abstract translation: 本发明涉及无菌多立培南的制备方法。

公开(公告)号：US20100311970A1

公开(公告)日：2010-12-09

申请号：US12745094

申请日：2008-04-30

Applicant: Neera Tewari ,  Dinesh Shashidharan Nair ,  Hashim Nizar Poovanathil Nagoor Meeran ,  Mohan Prasad

Inventor： Neera Tewari ,  Dinesh Shashidharan Nair ,  Hashim Nizar Poovanathil Nagoor Meeran ,  Mohan Prasad

IPC: C07D411/04

CPC classification number: C07D411/04

Abstract: The present invention relates to a process for the preparation of substituted 1,3-oxathiolanes. The present invention specifically relates to a process for the preparation of lamivudine.

Abstract translation: 本发明涉及一种制备取代的1,3-氧硫杂环戊烷的方法。 本发明具体涉及制备拉米夫定的方法。

公开(公告)号：US20090306173A1

公开(公告)日：2009-12-10

申请号：US12422602

申请日：2009-06-02

Applicant: Vipin TYAGI ,  Wajid Sajjad Jafri ,  Sanjay Kumar ,  Saridi Madhava Dileep Kumar ,  Swargam Sathyanarayana ,  Kaptan Singh ,  Mohan Prasad

Inventor： Vipin TYAGI ,  Wajid Sajjad Jafri ,  Sanjay Kumar ,  Saridi Madhava Dileep Kumar ,  Swargam Sathyanarayana ,  Kaptan Singh ,  Mohan Prasad

IPC: A61K31/40 ,  C07D207/34 ,  A61P9/10

CPC classification number: C07D207/34

Abstract: The present invention relates to crystalline forms of Atorvastatin magnesium and processes for their preparation. The crystalline forms of the present invention are designated as form X, form Y, form Z and form P of atorvastatin magnesium. The present invention further relates to pharmaceutical compositions comprising form X, form Y, form Z and form P of atorvastatin magnesium and method of using the crystalline forms.

Abstract translation: 本发明涉及阿托伐他汀镁的结晶形式及其制备方法。 本发明的结晶形式被称为形式X，形式Y，形式Z和阿托伐他汀镁的形式P. 本发明还涉及包含形式X，形式Y，形式Z和阿托伐他汀镁形式P的药物组合物和使用结晶形式的方法。

公开(公告)号：US20070060556A1

公开(公告)日：2007-03-15

申请号：US10555628

申请日：2004-05-03

Applicant: Yatendra Kumar ,  Mahavir Khanna ,  Mohan Prasad

Inventor： Yatendra Kumar ,  Mahavir Khanna ,  Mohan Prasad

IPC: A61K31/555 ,  A61K31/4439 ,  C07D403/02

CPC classification number: C07D401/12 ,  A61K31/4439

Abstract: A barium salt of the S-enantiomer of omeprazole which is (S)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methyl]sulfinyl]-1H-benzimidazole is provided. Further, processes for preparing the barium salt, pharmaceutical compositions comprising the salt and a method of treatment or prevention of gastrointestinal ulcers comprising administration of the salt are provided.

Abstract translation: 提供了（S）-5-甲氧基-2 - [[（4-甲氧基-3,5-二甲基-2-吡啶基） - 甲基]亚磺酰基] -1H-苯并咪唑的奥美拉唑的S-对映异构体的钡盐 。 此外，提供了制备钡盐的方法，包含该盐的药物组合物以及治疗或预防包括施用盐的胃肠溃疡的方法。

公开(公告)号：US20070037971A1

公开(公告)日：2007-02-15

申请号：US11461062

申请日：2006-07-31

Applicant: Hashim Nizar Meeran ,  Bishwa Rai ,  Shailendra Singh ,  Mohan Prasad

Inventor： Hashim Nizar Meeran ,  Bishwa Rai ,  Shailendra Singh ,  Mohan Prasad

IPC: C07D487/04 ,  C07D205/02

CPC classification number: C07D413/06 ,  C07D205/08 ,  C07D403/12

Abstract: Provided are processes for desilylating carbapenem intermediates. In particular, such desilylation reactions are done in the presence of one or more desilylating agents selected from acetyl chloride, silica chloride, thionyl chloride, oxalyl chloride or mixtures thereof.

Abstract translation: 提供了对碳青霉烯中间体脱甲基的方法。 特别地，这种脱甲硅烷基化反应在一种或多种选自乙酰氯，二氧化氯化物，亚硫酰氯，草酰氯或其混合物中的脱甲硅烷基化剂的存在下进行。