公开(公告)号：US10804091B2

公开(公告)日：2020-10-13

申请号：US16209140

申请日：2018-12-04

Applicant: PERKINELMER HEALTH SCIENCES CANADA, INC.

Inventor： Chady Stephan ,  Samad Bazargan

IPC: H01J49/10 ,  H01J49/00 ,  H01J49/26 ,  H01J49/16 ,  G01N30/72 ,  H01J49/04

Abstract: Methods and systems of identifying two or more elements in a single individual particle are described. In some examples, an optical emission from each of an ionized first element and an ionized second element can simultaneously be detected to identify at least a first element in a particle from a plurality of particles using the optical emission from the ionized first element, and to identify at least a second element in the particle from the plurality of particles using the optical emission from the second ionized element. The identified first element and the identified second element can be used to identify a source of the particle from a plurality of particles.

公开(公告)号：US20200161117A1

公开(公告)日：2020-05-21

申请号：US16551056

申请日：2019-08-26

Applicant: PERKINELMER HEALTH SCIENCES CANADA, INC.

Inventor： Chady Stephan ,  Hamid Badiei ,  Serguei Savtchenko ,  Samad Bazargan

IPC: H01J49/10 ,  H01J49/16 ,  H01J49/04 ,  G01N30/72

Abstract: Devices, systems and methods including a spray chamber are described. In certain examples, the spray chamber may be configured with an outer chamber configured to provide tangential gas flows. In other instances, an inner tube can be positioned within the outer chamber and may comprise a plurality of microchannels. In some examples, the outer chamber may comprise dual gas inlet ports. In some instances, the spray chamber may be configured to provide tangential gas flow and laminar gas flows to prevent droplet formation on surfaces of the spray chamber. Optical emission devices, optical absorption devices and mass spectrometers using the spray chamber are also described.

公开(公告)号：US20190341241A1

公开(公告)日：2019-11-07

申请号：US15970517

申请日：2018-05-03

Applicant: Perkinelmer Health Sciences Canada Inc.

Inventor： Frenny Kaushal ,  Gholamreza Javahery ,  Lisa Cousins ,  Charles Jolliffe

IPC: H01J49/16 ,  H01J49/06 ,  H01J49/42

Abstract: An ionizer includes a probe having multiple coaxially aligned conduits. The conduits may carry liquids, and nebulizing and heating gases at various flow rates and temperatures, for generation of ions from a liquid source. An outermost conduit defines an entrainment region that transports and entrains ions in a gas for a defined distance along the length of the conduits. In embodiments, various voltages may be applied to the multiple conduits to aid in ionization and to guide ions. Depending on the voltages applied to the multiple conduits and electrodes, the ionizer can act as an electrospray, APCI, or APPI source. Further, the ionizer may include a source of photons or a source of corona ionization. Formed ions may be provided to a downstream mass analyser.

公开(公告)号：US10395912B2

公开(公告)日：2019-08-27

申请号：US16146752

申请日：2018-09-28

Applicant: PERKINELMER HEALTH SCIENCES CANADA, INC.

Inventor： Chady Stephan ,  Hamid Badiei ,  Serguei Savtchenko ,  Samad Bazargan

IPC: H01J49/00 ,  H01J49/10 ,  H01J49/04 ,  H01J49/16 ,  G01N30/72

Abstract: Devices, systems and methods including a spray chamber are described. In certain examples, the spray chamber may be configured with an outer chamber configured to provide tangential gas flows. In other instances, an inner tube can be positioned within the outer chamber and may comprise a plurality of microchannels. In some examples, the outer chamber may comprise dual gas inlet ports. In some instances, the spray chamber may be configured to provide tangential gas flow and laminar gas flows to prevent droplet formation on surfaces of the spray chamber. Optical emission devices, optical absorption devices and mass spectrometers using the spray chamber are also described.