公开(公告)号：US10371773B2

公开(公告)日：2019-08-06

申请号：US16130712

申请日：2018-09-13

Applicant: Hyperfine Research, Inc.

Inventor： Michael Stephen Poole ,  Cedric Hugon ,  Hadrien A. Dyvorne ,  Laura Sacolick ,  William J. Mileski ,  Jeremy Christopher Jordan ,  Alan B. Katze, Jr. ,  Jonathan M. Rothberg ,  Todd Rearick ,  Christopher Thomas McNulty

IPC: G01R33/38 ,  G01R33/385 ,  G01R33/383 ,  G01R33/44 ,  G01R33/389 ,  G01R33/421 ,  G01R33/56 ,  A61B5/055 ,  A61B6/00 ,  A61G13/10 ,  G01R33/34 ,  G01R33/48 ,  A61B90/00 ,  A61B50/13 ,  G01R33/36 ,  G01R33/422 ,  G01R33/3873

Abstract: According to some aspects, a low-field magnetic resonance imaging system is provided. The low-field magnetic resonance imaging system comprises a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, the magnetics system comprising, a B0 magnet configured to produce a B0 field for the magnetic resonance imaging system at a low-field strength of less than 0.2 Tesla (T), a plurality of gradient coils configured to, when operated, generate magnetic fields to provide spatial encoding of magnetic resonance signals, and at least one radio frequency coil configured to, when operated, transmit radio frequency signals to a field of view of the magnetic resonance imaging system and to respond to magnetic resonance signals emitted from the field of view, a power system comprising one or more power components configured to provide power to the magnetics system to operate the magnetic resonance imaging system to perform image acquisition, and a power connection configured to connect to a single-phase outlet to receive mains electricity and deliver the mains electricity to the power system to provide power needed to operate the magnetic resonance imaging system. According to some aspects, the power system operates the low-field magnetic resonance imaging system using an average of less than 1.6 kilowatts during image acquisition.

公开(公告)号：US20190227136A1

公开(公告)日：2019-07-25

申请号：US16368931

申请日：2019-03-29

Applicant: Hyperfine Research, Inc.

Inventor： William J. Mileski ,  Gregory L. Charvat ,  Jonathan M. Rothberg ,  Jeremy Christopher Jordan

IPC: G01R33/385 ,  G01R33/46 ,  G05F1/46 ,  H03F3/45 ,  G01R33/38

Abstract: An apparatus to provide power for operating at least one gradient coil of a magnetic resonance imaging system. According to some aspects, the apparatus comprises a plurality of power terminals configured to supply different voltages of a first polarity, and a linear amplifier configured to provide at least one output to power the at least one gradient coil to produce a magnetic field in accordance with a pulse sequence, the linear amplifier configured to be powered by one or more of the plurality of power terminals, wherein the one or more of the plurality of power terminals powering the linear amplifier is selected based, at least in part, on the at least one output.

公开(公告)号：US10330755B2

公开(公告)日：2019-06-25

申请号：US15879203

申请日：2018-01-24

Applicant: Hyperfine Research, Inc.

Inventor： Michael Stephen Poole ,  Cedric Hugon ,  Hadrien A. Dyvorne ,  Laura Sacolick ,  William J. Mileski ,  Jeremy Christopher Jordan ,  Alan B. Katze, Jr. ,  Jonathan M. Rothberg ,  Todd Rearick ,  Christopher Thomas McNulty

IPC: G01R33/34 ,  G01R33/385 ,  G01R33/383 ,  G01R33/44 ,  G01R33/389 ,  G01R33/421 ,  G01R33/56 ,  G01R33/38 ,  A61B5/055 ,  A61B6/00 ,  A61G13/10 ,  G01R33/48 ,  A61B90/00 ,  A61B50/13 ,  G01R33/36 ,  G01R33/422 ,  G01R33/3873

Abstract: According to some aspects, a low power magnetic resonance imaging system is provided. The magnetic resonance imaging system comprises a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging. The magnetics system comprising a B0 magnet configured to produce a B0 field for the magnetic resonance imaging system, a plurality of gradient coils configured to, when operated, generate magnetic fields to provide spatial encoding of emitted magnetic resonance signals, and at least one radio frequency coil configured to, when operated, transmit radio frequency signals to the field of view of the magnetic resonance imaging system and to respond to magnetic resonance signals emitted from the field of view. The magnetic resonance imaging system further comprises a power system comprising one or more power components configured to provide power to the magnetics system to operate the magnetic resonance imaging system to perform image acquisition, wherein the power system operates the low-field magnetic resonance imaging system using an average of less than 1.6 kilowatts during image acquisition. According to some aspects, the magnetic resonance imaging system is a low-field magnetic resonance imaging system comprising a power connection configured to connect to a single-phase outlet to receive mains electricity and deliver the mains electricity to the power system to provide power needed to operate the magnetic resonance imaging system.

公开(公告)号：US10281540B2

公开(公告)日：2019-05-07

申请号：US15097433

申请日：2016-04-13

Applicant: Hyperfine Research, Inc.

Inventor： William J. Mileski ,  Gregory L. Charvat ,  Jonathan M. Rothberg ,  Jeremy Christopher Jordan

IPC: G01R33/00 ,  G01R33/385 ,  G05F1/46 ,  G01R33/38 ,  G01R33/46

Abstract: An apparatus to provide power for operating at least one gradient coil of a magnetic resonance imaging system. According to some aspects, the apparatus comprises a plurality of power terminals configured to supply different voltages of a first polarity, and a linear amplifier configured to provide at least one output to power the at least one gradient coil to produce a magnetic field in accordance with a pulse sequence, the linear amplifier configured to be powered by one or more of the plurality of power terminals, wherein the one or more of the plurality of power terminals powering the linear amplifier is selected based, at least in part, on the at least one output.

公开(公告)号：US10241177B2

公开(公告)日：2019-03-26

申请号：US15498432

申请日：2017-04-26

Applicant: Hyperfine Research, Inc.

Inventor： Michael Stephen Poole ,  Todd Rearick ,  Jonathan M. Rothberg

IPC: G01R33/56 ,  G01R33/36 ,  G01R33/38 ,  G01R33/385 ,  G01R33/44 ,  G01R33/58 ,  G01R33/48 ,  H01F7/02 ,  H01F7/06 ,  G01R33/381 ,  G01R33/383 ,  G01R33/3875 ,  G01R33/54 ,  G01R33/34 ,  G01R33/28 ,  G01R33/565 ,  G01R33/422

Abstract: In some aspects, a magnetic system for use in a low-field MRI system. The magnetic system comprises at least one electromagnet configured to, when operated, generate a magnetic field to contribute to a B0 field for the low-field MRI system, and at least one permanent magnet to produce a magnetic field to contribute to the B0 field.

公开(公告)号：US10222434B2

公开(公告)日：2019-03-05

申请号：US15879254

申请日：2018-01-24

Applicant: Hyperfine Research, Inc.

Inventor： Michael Stephen Poole ,  Cedric Hugon ,  Hadrien A. Dyvorne ,  Laura Sacolick ,  William J. Mileski ,  Jeremy Christopher Jordan ,  Alan B. Katze, Jr. ,  Jonathan M. Rothberg ,  Todd Rearick ,  Christopher Thomas McNulty

IPC: G01R33/385 ,  G01R33/383 ,  G01R33/44 ,  G01R33/389 ,  G01R33/421 ,  G01R33/56 ,  G01R33/38 ,  A61B5/055 ,  A61B6/00 ,  A61G13/10 ,  G01R33/34 ,  G01R33/48 ,  A61B90/00 ,  A61B50/13 ,  G01R33/36 ,  G01R33/422 ,  G01R33/3873

Abstract: According to some aspects, a portable magnetic resonance imaging system is provided, comprising a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging. The magnetics system comprises a permanent B0 magnet configured to produce a B0 field for the magnetic resonance imaging system, and a plurality of gradient coils configured to, when operated, generate magnetic fields to provide spatial encoding of emitted magnetic resonance signals, a power system comprising one or more power components configured to provide power to the magnetics system to operate the magnetic resonance imaging system to perform image acquisition, and a base that supports the magnetics system and houses the power system, the base comprising at least one conveyance mechanism allowing the portable magnetic resonance imaging system to be transported to different locations. According to some aspects, the base has a maximum horizontal dimension of less than or equal to approximately 50 inches. According to some aspects, the portable magnetic resonance imaging system weighs less than 1,500 pounds. According to some aspects, the portable magnetic resonance imaging system has a 5-Gauss line that has a maximum dimension of less than or equal to five feet.

公开(公告)号：US20190033414A1

公开(公告)日：2019-01-31

申请号：US16116389

申请日：2018-08-29

Applicant: Hyperfine Research, Inc.

Inventor： Michal Sofka ,  Jonathan M. Rothberg ,  Gregory L. Charvat ,  Tyler S. Ralston

IPC: G01R33/56 ,  G06K9/62 ,  A61B5/055 ,  A61B5/00 ,  G01R33/38 ,  G01R33/44 ,  G01R33/48 ,  G01R33/483 ,  G06T7/00 ,  G06N3/04 ,  G01R33/383

Abstract: Some aspects include a method of determining change in size of an abnormality in a brain of a patient positioned within a low-field magnetic resonance imaging (MRI) device. The method comprises, while the patient remains positioned within the low-field MRI device, acquiring first and second magnetic resonance (MR) image data of the patient's brain; providing the first and second MR image data as input to a trained statistical classifier to obtain corresponding first and second output; identifying, using the first output, at least one initial value of at least one feature indicative of a size of the abnormality; identifying, using the second output, at least one updated value of the at least one feature; determining the change in the size of the abnormality using the at least one initial value of the at least one feature and the at least one updated value of the at least one feature.

公开(公告)号：US20190018096A1

公开(公告)日：2019-01-17

申请号：US16123989

申请日：2018-09-06

Applicant: Hyperfine Research, Inc.

Inventor： Michael Stephen Poole ,  Cedric Hugon ,  Hadrien A. Dyvorne ,  Laura Sacolick ,  William J. Mileski ,  Jeremy Christopher Jordan ,  Alan B. Katze, JR. ,  Jonathan M. Rothberg ,  Todd Rearick ,  Christopher Thomas McNulty

IPC: G01R33/385 ,  G01R33/44 ,  G01R33/389 ,  A61B50/13 ,  A61B90/00

Abstract: According to some aspects, a portable magnetic resonance imaging system is provided, comprising a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging. The magnetics system comprises a permanent B0 magnet configured to produce a B0 field for the magnetic resonance imaging system, and a plurality of gradient coils configured to, when operated, generate magnetic fields to provide spatial encoding of emitted magnetic resonance signals, a power system comprising one or more power components configured to provide power to the magnetics system to operate the magnetic resonance imaging system to perform image acquisition, and a base that supports the magnetics system and houses the power system, the base comprising at least one conveyance mechanism allowing the portable magnetic resonance imaging system to be transported to different locations. According to some aspects, the base has a maximum horizontal dimension of less than or equal to approximately 50 inches. According to some aspects, the portable magnetic resonance imaging system weighs less than 1,500 pounds. According to some aspects, the portable magnetic resonance imaging system has a 5-Gauss line that has a maximum dimension of less than or equal to five feet.

公开(公告)号：US20190018095A1

公开(公告)日：2019-01-17

申请号：US16123941

申请日：2018-09-06

Applicant: Hyperfine Research, Inc.

Inventor： William J. Mileski ,  Gregory L. Charvat ,  Jonathan M. Rothberg ,  Jeremy Christopher Jordan

IPC: G01R33/385 ,  G05F1/46

Abstract: An apparatus to provide power for operating at least one gradient coil of a magnetic resonance imaging system. According to some aspects, the apparatus comprises a plurality of power terminals configured to supply different voltages of a first polarity, and a linear amplifier configured to provide at least one output to power the at least one gradient coil to produce a magnetic field in accordance with a pulse sequence, the linear amplifier configured to be powered by one or more of the plurality of power terminals, wherein the one or more of the plurality of power terminals powering the linear amplifier is selected based, at least in part, on the at least one output.

公开(公告)号：US10139464B2

公开(公告)日：2018-11-27

申请号：US15721309

申请日：2017-09-29

Applicant: Hyperfine Research, Inc.

Inventor： Todd Rearick ,  Gregory L. Charvat ,  Matthew Scot Rosen ,  Jonathan M. Rothberg

IPC: G01V3/00 ,  G01R33/56 ,  G01R33/36 ,  G01R33/38 ,  G01R33/385 ,  G01R33/44 ,  G01R33/58 ,  G01R33/48 ,  H01F7/02 ,  H01F7/06 ,  G01R33/381 ,  G01R33/383 ,  G01R33/3875 ,  G01R33/54 ,  G01R33/34 ,  G01R33/28 ,  G01R33/565 ,  G01R33/422

Abstract: According to some aspects, a method of suppressing noise in an environment of a magnetic resonance imaging system is provided. The method comprising estimating a transfer function based on multiple calibration measurements obtained from the environment by at least one primary coil and at least one auxiliary sensor, respectively, estimating noise present in a magnetic resonance signal received by the at least one primary coil based at least in part on the transfer function, and suppressing noise in the magnetic resonance signal using the noise estimate.