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公开(公告)号：US09636512B2
公开(公告)日：2017-05-02
申请号：US14932311
申请日：2015-11-04
Applicant: Medtronic, Inc.
Inventor： Can Cinbis , Vladimir P. Nikolski , Jian Cao , James K. Carney , Melissa G. T. Christie , Richard J. O'Brien , Amy E. Thompson-Nauman
CPC classification number: A61N1/3962 , A61N1/0587 , A61N1/3621 , A61N1/3918 , A61N1/3987
Abstract: This disclosure provides an extravascular ICD system and method for defibrillating a heart of a patient. The extravascular ICD system includes multiple extravascular electrical stimulation leads or lead segments located in close proximity to one another and having respective defibrillation electrodes. The ICD system utilizes the multiple defibrillation electrodes to form an extravascular electrode vector that may result a reduction in the shock impedance and/or a reduction in the DFT compared to extravascular ICD systems that include only a single extravascular defibrillation electrode. An ICD of the system may, for example, deliver a defibrillation shock using an electrode vector in which a first polarity of the electrode vector is formed by electrically coupling first and second defibrillation electrodes of first and second leads, respectively, to the therapy circuitry and a second polarity of the electrode vector is formed by electrically coupling a housing of the ICD to the therapy circuitry.
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公开(公告)号：US09138157B2
公开(公告)日：2015-09-22
申请号：US14056003
申请日：2013-10-17
Applicant: Medtronic, Inc.
Inventor： Amy E. Thompson-Nauman , Michael J Ebert , Rick D McVenes , Nathan A Grenz
IPC: A61N1/37 , A61B5/0402
CPC classification number: A61B5/0402 , A61B5/14546 , A61B5/686 , A61N1/0587 , A61N1/37247 , A61N1/37258 , A61N1/37264 , G16H40/63
Abstract: A method and medical device for monitoring cardiac function in a patient that includes a plurality of electrodes to deliver cardiac pacing therapy, and a processor configured to determine a pacing threshold in response to initial delivery of the pacing therapy, determine whether there is a change in the pacing threshold during initial delivery of the pacing therapy, adjust a delivery parameter of the pacing therapy in response to determining the change in the pacing threshold during initial delivery of the pacing therapy, determine whether there is an increase in the pacing threshold during delivery of the adjusted pacing therapy, and determine hypokalemia in response to the increase in the pacing threshold during delivery of the adjusted pacing therapy being present.
Abstract translation: 一种用于监测患者心脏功能的方法和医疗装置，所述方法和医疗装置包括多个用于递送心脏起搏疗法的电极，以及配置成响应于起搏治疗的初始递送确定起搏阈值的处理器，确定是否存在改变 在起搏治疗的初始递送期间的起搏阈值，响应于确定起搏治疗的初始递送过程中起搏阈值的变化，调整起搏治疗的递送参数，确定在分娩期间起搏阈值是否增加 调整的起搏治疗，并且响应于调节起搏治疗的递送期间起搏阈值的增加来确定低钾血症。
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公开(公告)号：US20140330331A1
公开(公告)日：2014-11-06
申请号：US14261488
申请日：2014-04-25
Applicant: Medtronic, Inc.
Inventor： Amy E. Thompson-Nauman , Melissa G.T. Christie , Paul J. DeGroot , Rick D. McVenes
Abstract: Implantable leadless cardiac pacing systems and methods for providing substernal pacing using the leadless cardiac pacing systems are described. In one embodiment, an implantable leadless cardiac pacing system includes a housing, a first electrode on the housing, a second electrode on the housing, and a pulse generator within the housing and electrically coupled to the first electrode and the second electrode. The housing is implanted substantially within an anterior mediastinum of a patient and the pulse generator is configured to deliver pacing pulses to a heart of the patient via a therapy vector formed between the first and second electrodes.
Abstract translation: 描述了可植入无引心心脏起搏系统和使用无引心心脏起搏系统提供下位起搏的方法。 在一个实施例中，可植入无引心心脏起搏系统包括壳体，壳体上的第一电极，壳体上的第二电极以及壳体内的脉冲发生器，并且电耦合到第一电极和第二电极。 壳体基本上植入患者的前纵隔中，并且脉冲发生器被配置为经由形成在第一和第二电极之间的治疗矢量将起搏脉冲输送到患者的心脏。
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64.发明申请IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR (ICD) SYSTEM INCLUDING SUBSTERNAL LEAD 审中-公开可植入式除颤器（ICD）系统，包括后置引线公开(公告)号：US20140330327A1
公开(公告)日：2014-11-06
申请号：US14261470
申请日：2014-04-25
Applicant: Medtronic, Inc.
Inventor： Amy E. Thompson-Nauman , Melissa G.T. Christie , Paul J. DeGroot , Rick D. McVenes , Becky L. Dolan
CPC classification number: A61N1/3962 , A61N1/05 , A61N1/3956
Abstract: Substernal implantable cardioveter-defibrillator (ICD) systems and methods for providing substernal electrical stimulation therapy to treat malignant tachyarrhythmia, e.g., ventricular tachycardia (VT) and ventricular fibrillation (VF) are described. In one example, an implantable cardioveter-defibrillator (ICD) system includes an ICD implanted in a patient and an implantable medical electrical lead. The lead includes an elongated lead body having a proximal end and a distal portion, a connector at the proximal end of the lead body configured to couple to the ICD, and one or more electrodes along the distal portion of the elongated lead body. The distal portion of the elongated lead body of the lead is implanted substantially within an anterior mediastinum of the patient and the ICD is configured to deliver electrical stimulation to a heart of the patient using the one or more electrodes.
Abstract translation: 描述了用于治疗恶性快速性心律失常，例如室性心动过速（VT）和心室颤动（VF）的基础植入式心脏除颤器（ICD）系统和用于提供次要电刺激治疗的方法。 在一个示例中，植入式心脏除颤器（ICD）系统包括植入患者体内的ICD和可植入医用电导线。 引线包括具有近端和远端部分的细长引线体，在引线本体的近端处的连接器，其被配置为耦合到ICD，以及沿着细长引线体的远端部分的一个或多个电极。 引线的细长引线体的远端部分基本上植入患者的前纵隔，并且ICD构造成使用一个或多个电极将电刺激递送到患者的心脏。
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公开(公告)号：US20140330287A1
公开(公告)日：2014-11-06
申请号：US14257462
申请日：2014-04-21
Applicant: Medtronic, Inc.
Inventor： Amy E. Thompson-Nauman , Melissa G.T. Christie
IPC: A61N1/05
CPC classification number: A61N1/05 , A61N1/057 , A61N1/0573 , A61N1/3956 , A61N2001/0578 , A61N2001/058
Abstract: Anchoring mechanisms for an implantable electrical medical lead that is positioned within a substernal space are disclosed. The anchoring mechanisms fixedly-position a distal portion of the lead, that is implanted in the substernal space.
Abstract translation: 公开了一种位于下层空间内的可植入电气医疗引线的固定机构。 锚固机构固定地定位引线的远端部分，其被植入在下层空间中。
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Patent Agency Ranking
公开(公告)号：US20140330248A1
公开(公告)日：2014-11-06
申请号：US14257549
申请日：2014-04-21
Applicant: Medtronic, Inc.
Inventor： Amy E. Thompson-Nauman , Melissa G.T. Christie , Noah D. Barka
IPC: A61N1/05
CPC classification number: A61N1/05 , A61B17/3462 , A61B17/3468 , A61B17/3494 , A61B2017/00243 , A61B2017/00331 , A61B2017/00455 , A61B2017/320056 , A61M5/14 , A61N1/0504 , A61N1/0563
Abstract: Implant tools and techniques for implantation of a medical lead, catheter or other implantable component are provided. The implant tools and techniques are particularly useful in implanting medical electrical leads in implant locations such as substernal spaces or subcutaneous locations. The implant tools include a sheath coupled to a sealing device. The sheath includes a continuous lumen that is in fluid communication with a passage of the sealing device. The lead is advanced through the passage and the lumen for placement of the distal end of the lead at the implant location.
Abstract translation: 提供用于植入医疗引线，导管或其它可植入部件的植入物工具和技术。 植入物工具和技术在植入医疗电引线在植入位置例如下位空间或皮下位置中特别有用。 植入工具包括耦合到密封装置的护套。 鞘包括与密封装置的通道流体连通的连续内腔。 引线通过通道和内腔前进，以将铅的远端放置在植入位置。
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67.发明授权公开(公告)号：US12178470B2
公开(公告)日：2024-12-31
申请号：US17397276
申请日：2021-08-09
Applicant: Medtronic, Inc.
Inventor： Ronald A. Drake , Kevin R. Seifert , Lester O. Stener , Amy E. Thompson-Nauman
Abstract: Extravascular implant tools that utilize a bore-in mechanism to safely access extravascular locations and implant techniques utilizing these tools are described. The bore-in mechanism may include a handle and a helix extending from the handle. The bore-in mechanism is used, for example, in conjunction with a tunneling tool to traverse the diaphragmatic attachments to access a substernal location. The tunneling tool may be an open channel tunneling tool or a conventional tunneling tool (e.g., metal rod).
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公开(公告)号：US12144979B2
公开(公告)日：2024-11-19
申请号：US16990321
申请日：2020-08-11
Applicant: Medtronic, Inc.
Inventor： Mark T. Marshall , Amy E. Thompson-Nauman , Melissa G. T. Christie , Gonzalo Martinez , Kevin R. Seifert
Abstract: A lead body having a defibrillation electrode positioned along a distal portion of the lead body is described. The defibrillation electrode includes a plurality of electrode segments spaced a distance apart from each other. At least one of the plurality of defibrillation electrode segments includes at least one coated portion and at least one uncoated portion. The at least one coated portion is coated with an electrically insulating material configured to prevent transmission of a low voltage signal (e.g., a pacing pulse) while allowing transmission of a high voltage signal (e.g., a cardioversion defibrillation shock). The at least one uncoated portion is configured to transmit both low voltage and high voltage signals. The lead may also include one or more discrete electrodes proximal, distal or between the defibrillation electrode segments.
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公开(公告)号：US12059568B2
公开(公告)日：2024-08-13
申请号：US18324689
申请日：2023-05-26
Applicant: Medtronic, Inc.
Inventor： Amy E. Thompson-Nauman , Melissa G. T. Christie , Mark T. Marshall , Thomas H. Spear
CPC classification number: A61N1/36521 , A61N1/3706 , A61N1/3925 , A61N1/3956
Abstract: An extra-cardiovascular medical device is configured to select a capacitor configuration from a capacitor array and deliver a low voltage, pacing pulse by discharging the selected capacitor configuration across an extra-cardiovascular pacing electrode vector. In some examples, the medical device is configured to determine the capacitor configuration based on a measured impedance of the extra-cardiovascular pacing electrode vector.
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公开(公告)号：US11986213B2
公开(公告)日：2024-05-21
申请号：US17492102
申请日：2021-10-01
Applicant: Medtronic, Inc.
Inventor： Vladimir P. Nikolski , Linnea R. Lentz , Amy E. Thompson-Nauman , Teresa A Whitman , Mark T. Marshall
CPC classification number: A61B17/3468 , A61B17/00234 , A61B17/3415 , A61M25/008 , A61N1/0504 , A61B2017/00331 , A61B2017/320056 , A61B17/3494 , A61M25/0194 , A61N1/3968
Abstract: In some examples, a system includes a medical device comprising an elongate body configured to advance through layers of tissue of a patient, a lumen extending through the elongate body, a fluid line configured to supply fluid to the lumen, and a pressure sensor positioned within the lumen or the fluid line. The system may further include processing circuitry configured to receive, from the pressure sensor, a signal corresponding to the pressure of the fluid at each of a plurality of time points, determine, for each time point: a corresponding amplitude value of the signal, a difference between two amplitude values of the signal, an amplitude oscillation status of the signal, a position of the elongate body based on the difference and the amplitude oscillation status; and provide an indication of the position of the elongate body relative to the layers of tissue.
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