Method of treating oral inflammatory disease
    63.
    发明授权
    Method of treating oral inflammatory disease 失效
    治疗口腔炎症的方法

    公开(公告)号:US5512299A

    公开(公告)日:1996-04-30

    申请号:US092024

    申请日:1993-07-14

    IPC分类号: A61K9/00 A61K9/22 A61K9/20

    摘要: A method of treating inflammatory disease of the mouth by locally delivering beclomethasone dipropionate and related compounds to the oral cavity of a patient over an extended period of time is disclosed. In one embodiment, beclomethasone dipropionate is delivered by an osmotic device (10), in another embodiment, it is delivered by an erosion controlled device (110) and in yet another embodiment, it is delivered by a diffusion controlled device (310).

    摘要翻译: 公开了一种通过在长时间内将二丙酸倍氯米松和相关化合物局部递送到患者的口腔来治疗口腔炎症的方法。 在一个实施方案中,二丙酸倍氯米松通过渗透装置(10)递送,在另一个实施方案中,其由侵蚀受控装置(110)递送,并且在另一个实施方案中,其由扩散控制装置(310)递送。

    Osmotically-driven fluid dispenser
    67.
    发明授权
    Osmotically-driven fluid dispenser 失效
    渗透驱动的流体分配器

    公开(公告)号:US07335193B2

    公开(公告)日:2008-02-26

    申请号:US10885188

    申请日:2004-07-06

    IPC分类号: A61K9/22

    摘要: Improvements in a mini-osmotic pump and coating compositions are described. The dispensing pump includes an inner fluid-filled bag encased by an osmotic layer and outer, semi-permeable membrane. The inner bag is formed with an arcuate edge at the open end of the bag to inhibit formation of fissures in the outer membrane in this edge region. The coating compositions include cellulose acetate butyrate, cellulose acetate propionate, and polymethylmethacrylate polymers, optionally mixed with ethyl cellulose in acetone based solvent systems.

    摘要翻译: 描述了微型渗透泵和涂料组合物的改进。 分配泵包括由渗透层和外部半透膜封装的内部充满液体的袋。 内袋在袋的开口端处形成有弧形边缘,以防止在该边缘区域中的外膜中的裂缝的形成。 涂料组合物包括乙酸丁酸纤维素,乙酸丙酸纤维素和聚甲基丙烯酸甲酯聚合物,任选地与丙酮基溶剂体系中的乙基纤维素混合。