公开(公告)号：US5026917A

公开(公告)日：1991-06-25

申请号：US486783

申请日：1990-03-01

Applicant: Gary P. Hagen ,  Gregory E. Schmidt ,  John M. Weis ,  Thomas G. Smith

Inventor： Gary P. Hagen ,  Gregory E. Schmidt ,  John M. Weis ,  Thomas G. Smith

IPC: C07C45/46 ,  C07C45/80 ,  C07C45/81 ,  C07C45/82

CPC classification number: C07C45/82 ,  C07C45/46 ,  C07C45/80 ,  C07C45/81

Abstract: A regioselective acetylation process is provided for converting a 2-methylnaphthalene compound to a 2-acetyl-6-methylnaphthalene compound. The process is conducted under liquid phase conditions using a new complexing agent which is regiospecific for the beta position of naphthalene and which is an electron-rich, carbon-based compound. A preferred such agent is hexamethylbenzene. Also provided is a novel method for producing a 2-acetyl-6-methylnaphthalene compound of relative high purity from isomer mixtures by recrystallization from a hydrocarbon solvent, such as n-octane, isooctane, or n-nonane.

Abstract translation: 提供了一种区域选择性乙酰化方法，用于将2-甲基萘化合物转化为2-乙酰基-6-甲基萘化合物。 该方法在液相条件下使用对于萘的β位具有区域特异性，并且是富电子的碳基化合物的新的络合剂进行。 优选的这种试剂是六甲基苯。 还提供了通过从烃溶剂如正辛烷，异辛烷或正壬烷中重结晶制备异构体混合物中相对高纯度的2-乙酰基-6-甲基萘化合物的新方法。

公开(公告)号：US4892625A

公开(公告)日：1990-01-09

申请号：US65481

申请日：1987-06-23

Applicant: Shumpei Shimizu ,  Mamoru Yoshizako ,  Toshitsura Cho

Inventor： Shumpei Shimizu ,  Mamoru Yoshizako ,  Toshitsura Cho

IPC: B01D3/00 ,  B01D3/16 ,  B01D3/22 ,  C01B7/07 ,  C01B7/13 ,  C01B7/19 ,  C01B11/16 ,  C01B21/46 ,  C07C17/383 ,  C07C45/78 ,  C07C45/81 ,  C07C45/82 ,  C07C51/44

CPC classification number: C07C51/44 ,  B01D3/00 ,  C01B11/16 ,  C01B21/46 ,  C01B7/0712 ,  C01B7/135 ,  C01B7/196 ,  C07C17/383 ,  C07C45/78 ,  C07C45/81 ,  C07C45/82 ,  Y10S203/11

Abstract: A distillable liquid containing non-volatile impurities is freed of those impurities by boiling the liquid to form vapors of the liquid, passing the vapors through a packed column heated to a temperature such that liquid entrained in the vapors is completely vaporized and the non-volatile impurities remain in the packed column, and condensing the vapors from the column.

公开(公告)号：US4889952A

公开(公告)日：1989-12-26

申请号：US166633

申请日：1988-03-11

Applicant: Isoo Shimizu ,  Yasuo Matsumura ,  Yutaka Arai

Inventor： Isoo Shimizu ,  Yasuo Matsumura ,  Yutaka Arai

IPC: C07C59/84 ,  B01J31/16 ,  B01J31/24 ,  C07B61/00 ,  C07C5/333 ,  C07C15/50 ,  C07C45/50 ,  C07C45/82 ,  C07C47/232 ,  C07C47/32 ,  C07C51/00 ,  C07C51/235 ,  C07C51/245 ,  C07C51/255 ,  C07C51/373 ,  C07C67/00

CPC classification number: C07C51/255 ,  C07C15/50 ,  C07C45/50 ,  C07C45/82 ,  C07C47/232 ,  C07C47/32 ,  C07C5/3332 ,  C07C51/245 ,  C07C51/373

Abstract: A novel compound of .alpha.-(3-(1-phenylethenyl)phenyl)-propionaldehyde and a method for producing .alpha.-(3-benzoylphenyl)propionic acid which is prepared by oxidizing the former compound as an intermediate. The method is characterized in the easiness in operation, the low cost and the high purity of the product.

公开(公告)号：US4885399A

公开(公告)日：1989-12-05

申请号：US218693

申请日：1988-07-13

Applicant: Stanley F. Newman ,  Jacques C. De Deken ,  Michael L. Cook

Inventor： Stanley F. Newman ,  Jacques C. De Deken ,  Michael L. Cook

IPC: C07C45/34 ,  C07C45/80 ,  C07C45/82 ,  C07C45/85

CPC classification number: C07C45/82 ,  C07C45/34 ,  C07C45/80 ,  C07C45/85

Abstract: Tischtschenko condensation of aldehydes is used to remove aldehydes from dry ketone-containing streams. The tischtschenko condensation is used to condense the aldehydes into esters whose boiling points are significantly different than the ketones, greatly simplifying the separation of the esters from the ketones. An organic extraction step is used to obtain a substantially dry ketone containing stream. One particularly preferred class of extraction solvents is selected from the group consisting of butane, pentane, hexane, heptane, octane, nonane, decane and mixtures thereof. In particularly preferred embodiments, the Tischtschenko reaction is used in the context of aqueous-phase catalyzed olefin oxidation to ketones. The aldehyde to ester condensation permits easy and efficient removal of the aldehyde analogs of the desired ketones.

公开(公告)号：US4814512A

公开(公告)日：1989-03-21

申请号：US945303

申请日：1986-12-19

Applicant: Michio Ueshima ,  Yoshiyuki Takahashi ,  Masatoshi Tsuchino ,  Noboru Saito

Inventor： Michio Ueshima ,  Yoshiyuki Takahashi ,  Masatoshi Tsuchino ,  Noboru Saito

IPC: C07C45/36 ,  C07C45/78 ,  C07C45/81 ,  C07C45/82 ,  C07C45/32

CPC classification number: C07C45/81 ,  C07C45/36 ,  C07C45/78 ,  C07C45/82

Abstract: A method for the production of p-methoxybenzaldehyde by the vapor-phase catalytic oxidation of p-methoxytoluene, which method comprises cooling and condensing a mixed gas formed by said reaction of oxidation thereby preparing a solution containing p-methoxybenzaldehyde, treating said solution in the presence of at least one alkali selected from the group consisting of an alkali metal compound and an ammonium compound soluble in water and alkaline in nature, and subsequently distilling the resultant treated solution.

Abstract translation: 通过对甲氧基甲苯的气相催化氧化生产对甲氧基苯甲醛的方法，该方法包括冷却和冷凝通过氧化反应形成的混合气体，从而制备含有对甲氧基苯甲醛的溶液， 存在选自碱金属化合物和本质上可溶于水和碱的铵化合物的至少一种碱，然后蒸馏得到的处理溶液。

公开(公告)号：US4559110A

公开(公告)日：1985-12-17

申请号：US512508

申请日：1983-07-11

Applicant: Loren L. Swearingen ,  Alfred W. Heinsohn ,  Craig W. Snook ,  Wallace E. Embrey ,  Garnet E. McConchie

Inventor： Loren L. Swearingen ,  Alfred W. Heinsohn ,  Craig W. Snook ,  Wallace E. Embrey ,  Garnet E. McConchie

IPC: B01D3/10 ,  B01D3/40 ,  C07C45/80 ,  C07C45/82 ,  C07C45/85

CPC classification number: C07C45/80 ,  B01D3/10 ,  B01D3/40 ,  C07C45/82 ,  C07C45/85

Abstract: Distillation of the heavy waste stream from the manufacture of phenol via the cumene process provides an overhead stream containing phenol, acetophenone and 2-phenyl propionaldehyde. Extraction of the overhead stream with aqueous caustic removes the phenol and subsequent distillation of the remaining two components in the presence of a catalytic amount of caustic provides a substantially pure acetophenone distillate.

Abstract translation: 通过异丙苯法从苯酚的制造中蒸馏重质废物流提供了含苯酚，苯乙酮和2-苯基丙醛的塔顶物流。 用苛性碱水溶液萃取塔顶馏出物，除去苯酚，随后在催化量苛性碱的存在下蒸馏剩余的两种组分，提供基本上纯的苯乙酮馏出物。

公开(公告)号：US4511751A

公开(公告)日：1985-04-16

申请号：US540870

申请日：1983-10-11

Applicant: Yoichi Ninagawa ,  Osamu Yamada ,  Tsumoru Renge ,  Sunao Kyo ,  Takayoshi Osaki ,  Koichi Kushida

Inventor： Yoichi Ninagawa ,  Osamu Yamada ,  Tsumoru Renge ,  Sunao Kyo ,  Takayoshi Osaki ,  Koichi Kushida

IPC: C07C1/20 ,  C07C2/86 ,  C07C29/40 ,  C07C45/00 ,  C07C45/81 ,  C07C45/82 ,  C07D309/18 ,  C07D319/06 ,  C07C11/18

CPC classification number: C07D319/06 ,  C07C1/20 ,  C07C2/867 ,  C07C29/40 ,  C07C45/00 ,  C07C45/81 ,  C07C45/82 ,  C07D309/18

Abstract: A process for producing isoprene in good yield is provided. The process is characterized in that isobutene and/or tertiary butanol and a formaldehyde source are fed, together with water, into an acidic aqueous solution continuously or intermittently while maintaining the reaction pressure in an adequate range and at the same time distilling off the product isoprene and unreacted starting materials, together with water, from the reaction zone.

Abstract translation: 提供了以良好的产率生产异戊二烯的方法。 该方法的特征在于将异丁烯和/或叔丁醇和甲醛源与水一起连续或间歇地进料到酸性水溶液中，同时保持反应压力在适当的范围内，同时蒸除产物异戊二烯 和来自反应区的未反应的起始原料与水一起。

公开(公告)号：US4496768A

公开(公告)日：1985-01-29

申请号：US501859

申请日：1983-06-07

Applicant: Alan J. Dennis ,  George E. Harrison ,  James P. Wyber

Inventor： Alan J. Dennis ,  George E. Harrison ,  James P. Wyber

IPC: B01J31/00 ,  B01J31/20 ,  B01J31/22 ,  C07B61/00 ,  C07C45/00 ,  C07C45/50 ,  C07C45/82 ,  C07C47/02 ,  C07C67/00 ,  C07F15/00

CPC classification number: B01J31/185 ,  B01J31/20 ,  C07C45/50 ,  C07C45/82 ,  C07F15/008 ,  B01J2231/321 ,  B01J2531/822

Abstract: A continuous process for the production an aldehyde by hydroformylation of an optionally substituted alpha-olefin comprises:providing a hydroformylation zone containing a charge of a liquid reaction medium having dissolved therein a complex rhodium hydroformylation catalyst comprising rhodium in complex combination with carbon monoxide and with a cyclic phosphite having a bridgehead phosphorus atom linked to three oxygen atoms at least two of which form together with the bridgehead phosphorus atom part of a ring;supplying said alpha-olefin to the hydroformylation zone;maintaining temperature and pressure conditions in the hydroformylation zone conducive to hydroformylation of the alpha-olefin;supplying make-up hydrogen and carbon monoxide to the hydroformylation zone; andrecovering from the liquid hydroformylation medium a hydroformylation product comprising at least one aldehyde.

Abstract translation: 用于通过任选取代的α-烯烃的羰基化生产醛的连续方法包括：提供含有液体反应介质的加氢甲酰化区，该液体反应介质溶解有复合铑加氢甲酰化催化剂，其包含与一氧化碳复合组合的铑 环状亚磷酸酯，其具有连接至三个氧原子的桥头磷原子，其中至少两个与桥环磷原子部分一起形成; 将所述α-烯烃供应到加氢甲酰化区; 维持加氢甲酰化区中有利于α-烯烃加氢甲酰化的温度和压力条件; 向加氢甲酰化区提供补充氢和一氧化碳; 并从液体加氢甲酰化介质中回收含有至少一种醛的加氢甲酰化产物。

公开(公告)号：US4479012A

公开(公告)日：1984-10-23

申请号：US363565

申请日：1982-03-30

Applicant: Karl Fischer ,  Armin V. Grenacher ,  Manfred Herr ,  Max Strohmeyer

Inventor： Karl Fischer ,  Armin V. Grenacher ,  Manfred Herr ,  Max Strohmeyer

IPC: B01J23/00 ,  B01J23/46 ,  C07B61/00 ,  C07C45/00 ,  C07C45/50 ,  C07C45/81 ,  C07C45/82 ,  C07C47/02 ,  C07C67/00 ,  B01D3/14

CPC classification number: C07C45/81 ,  C07C45/50 ,  C07C45/82 ,  Y02P20/582 ,  Y10S203/06 ,  Y10S203/09

Abstract: Aldehydes are obtained from the gaseous product of the hydroformylation of olefinically unsaturated compounds using a rhodium catalyst by a process (cf. FIG. 2) in which(a) this gaseous product is introduced, without being cooled or depressured, into a distillation column D,(b) the top fraction from this column is cooled in a condenser K so that the greater part of the aldehydes contained therein is condensed,(c) the condensate is separated, in a separator A, into a gas phase and a liquid phase,(d) the gas phase from A, after waste gas has been separated off, is again brought to the hydroformylation pressure by means of a compressor P, and is returned to the reactor as a recycle gas,(e) the liquid phase from A is returned to D, and(f) the aldehydes are taken off from column D as liquid bottom products and/or as a vaporous side stream.

Abstract translation: 醛通过使用铑催化剂的方法（参见图2）从烯属不饱和化合物的加氢甲酰化的气态产物获得，其中（a）将该气态产物不经冷却或减压引入蒸馏塔D ，（b）将该塔的顶部馏分在冷凝器K中冷却，使其中含有的大部分醛缩合，（c）冷凝物在分离器A中分离成气相和液相 ，（d）在废气分离后，来自A的气相再次通过压缩机P进入加氢甲酰化反应器，并作为循环气体返回到反应器，（e）液相从 A返回到D，和（f）醛作为液体底部产物和/或作为蒸气侧流从塔D中取出。

公开(公告)号：US4340447A

公开(公告)日：1982-07-20

申请号：US267603

申请日：1981-05-27

Applicant: Robert G. Laverick ,  James M. Scotland

Inventor： Robert G. Laverick ,  James M. Scotland

IPC: C07C49/08 ,  C07C45/00 ,  C07C45/53 ,  C07C45/81 ,  C07C45/82 ,  C07C67/00 ,  B01D3/34

CPC classification number: C07C45/81 ,  C07C45/53 ,  C07C45/82 ,  Y10S203/20

Abstract: Pure acetone is recovered from a crude acetone vapor fraction removed overhead from a first column separating phenol and higher boilers as a bottom fraction from a cumene hydroperoxide cleavage reaction product by partially condensing the crude acetone fraction, returning the condensed portion of the crude acetone fraction to the first column as reflux, feeding the remaining portion as a vapor to an intermediate point in a second distillation column to which there is also fed continuously at a point above the acetone feedpoint a dilute aqueous solution of an alkali, removing from the base of the second column a residue fraction comprising compounds boiling above acetone, removing from a point in the second column intermediate; between the alkali feedpoint and the top of the column as a liquid sidedraw fraction pure acetone having a permanganate time (PT) greater than 4 hours, and removing from the top of the second column as a vapor fraction acetone having a PT less than that of the sidedraw fraction, condensing the acetone vapor fraction and returning to the second column at a point above the liquid acetone sidedraw removal point a portion of the condensate as reflux.

Abstract translation: 从粗制丙酮蒸气馏分中回收纯丙酮蒸气馏分，该塔顶馏出物通过部分冷凝粗丙酮馏分，将粗丙酮馏分的冷凝部分返回至粗丙酮馏分的冷凝部分，从第一塔分离苯酚和较高沸点作为底部馏分，由氢过氧化枯烯裂解反应产物 第一塔作为回流，将剩余部分作为蒸气输送到第二蒸馏塔中的中间点，在第二蒸馏塔中还在丙酮给料点上方连续供给稀碱水溶液，从碱 第二列是包含沸点高于丙酮的化合物的残余馏分，从第二塔中间体的一个点去除; 在碱进料点和塔顶之间，作为大于4小时的高锰酸盐时间（PT）的液体双侧馏分纯丙酮，并且从第二塔的顶部除去PT的蒸气馏分丙酮，其PT比 侧面馏分，冷凝丙酮蒸气馏分，并在液体丙酮侧面抽出点上方的一个位置返回到第二塔，将一部分冷凝物作为回流。