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    Stowable utility trailer
    71.
    发明授权
    Stowable utility trailer 失效
    可储存的实用拖车

    公开(公告)号：US5743541A

    公开(公告)日：1998-04-28

    申请号：US661826

    申请日：1996-06-11

    Applicant: Michael James Cook

    Inventor： Michael James Cook

    IPC: B62D63/06

    CPC classification number: B62D63/061

    Abstract: A light weight utility trailer which may be readily converted between an operative and a stowable configuration includes a bed or body that pivotally carries a stud shaft to which a tow bar is secured. A pair of wheels are supported by a shaft pivotally connected to the bed. A first sprocket is secured to the pivot shaft and a second sprocket secured to the wheel support shaft, and a chain is trained about both sprockets. When the tow bar is rotated from the operative position extending forwardly of the bed to a stowable position beneath the bed, the stud shaft is thereby rotated and rotates the wheel support shaft by means of the chain from the operative position extending downwardly beyond the bottom of the bed to an inoperative position wherein the wheels are raised above the bottom of the bed. In the stowable position the wheels are within the profile of the sides of the bed and thus the trailer may be stowed in a minimum of space. Springs are provided to bias the wheel support shaft to rotate toward the operative position until the tow bar has been moved beyond a mid-point position in its travel toward the stowable position, at which time the springs move over-center and urge the wheel support shaft to the stowable position. Fenders are provided above the wheels in the operative position and are moved to a stowable position as the wheels are moved.

    Abstract translation: 可以在操作和可收起构型之间容易地转换的轻量级有用拖车包括枢转地承载固定有拖杆的螺柱轴的床或主体。 一对车轮由枢转地连接到床的轴支撑。 第一链轮被固定到枢转轴和固定到车轮支撑轴的第二链轮，并且围绕两个链轮训练链条。 当拖杆从床的前方的操作位置旋转到床下方的可收起位置时，螺柱轴由此旋转，并且通过链从下方延伸的操作位置使车轮支撑轴向下延伸超过 床到不工作位置，其中车轮升高到床的底部之上。 在收起位置，车轮在床的侧面的轮廓内，因此拖车可以被存放在最小的空间中。 提供弹簧以偏置车轮支撑轴以朝向操作位置旋转，直到牵引杆已经移动超过其行进中的可收起位置的中点位置，此时弹簧移动超过中心并且推动车轮支撑件 轴到收起位置。 挡板设置在车轮上方的工作位置，并随车轮移动而移动到收起位置。

    MODIFIED ANTI-INFLAMMATORY PROTEINS AND METHOD OF USE
    78.
    发明申请
    MODIFIED ANTI-INFLAMMATORY PROTEINS AND METHOD OF USE 有权

    公开(公告)号：US20210061886A1

    公开(公告)日：2021-03-04

    申请号：US17071563

    申请日：2020-10-15

    Applicant: James Cook University

    Inventor： Alex Loukas ,  Andrew Leech ,  Darren Pickering

    IPC: C07K14/81 ,  A61K45/06 ,  C07K14/435 ,  A61K38/57

    Abstract: A modified Ac-TMP-2 protein lacks one or a plurality of acidic C-terminal amino acids normally present in a full-length or wild-type Ac-TMP-2 protein and may also lack one or a plurality of N-terminal amino acids while retaining the amino acid sequence C-S-C at or near the N-terminus. The modified Ac-TMP-2 protein may be useful in method and composition for reducing or alleviating inflammation in a subject. Inflammation may be associated with a disease is a disease of the digestive tract such as chronic gastritis or an inflammatory bowel disease such as Crohn's disease or ulcerative colitis, or a disease of the respiratory system, such as asthma, emphysema, chronic bronchitis, and chronic obstructive pulmonary disease.

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