公开(公告)号：US07966236B2

公开(公告)日：2011-06-21

申请号：US10885321

申请日：2004-07-07

Applicant: Carla Noriega ,  Elizabeth L Pedersen ,  David Christensen ,  Mark Lipschutz ,  Andre Kupelian ,  Keyur Patel ,  Takshing Andy Chow ,  Olga Konratev ,  Ellen Brill ,  Angelo Diamantidis

Inventor： Carla Noriega ,  Elizabeth L Pedersen ,  David Christensen ,  Mark Lipschutz ,  Andre Kupelian ,  Keyur Patel ,  Takshing Andy Chow ,  Olga Konratev ,  Ellen Brill ,  Angelo Diamantidis

IPC: G06Q40/00

CPC classification number: G06Q40/00 ,  G06Q20/105 ,  G06Q40/04 ,  G06Q40/06 ,  G06Q40/12

Abstract: Methods and systems for real time margin management are provided. A margin inquiry request from a user is processed in real time. Such a margin inquiry request may include a real time on-demand margin inquiry. In addition, a margin inquiry request may also correspond to a hypothetical margin inquiry.

Abstract translation: 提供实时保证金管理的方法和系统。 来自用户的保证金查询请求被实时处理。 这样的保证金查询请求可以包括实时按需保证金查询。 此外，保证金查询请求也可对应于假设的保证金查询。

公开(公告)号：US07957306B2

公开(公告)日：2011-06-07

申请号：US11518383

申请日：2006-09-08

Applicant: Stewart F. Bryant ,  Mike Shand ,  Gargi Nalawade ,  Robert Raszuk ,  Keyur Patel ,  David D. Ward ,  Clarence Filsfils ,  Stefano B. Previdi

Inventor： Stewart F. Bryant ,  Mike Shand ,  Gargi Nalawade ,  Robert Raszuk ,  Keyur Patel ,  David D. Ward ,  Clarence Filsfils ,  Stefano B. Previdi

IPC: H04L12/26 ,  H04L12/66 ,  G06F15/16

CPC classification number: H04L45/22 ,  H04L45/02 ,  H04L45/04 ,  H04L45/28

Abstract: An apparatus for providing reachability in a routing domain of a data communications network having as components nodes and links therebetween for a routing domain external destination address is provided. The apparatus is arranged to advertise destination address reachability internally to nodes in the routing domain and associate a reachability category with the internal advertisement of the destination address reachability.

Abstract translation: 提供了一种用于在数据通信网络的路由域中提供可达性的装置，其具有用于路由域外部目的地地址的节点和链路之间的组件。 该设备被布置为在路由域中的节点内部向目的地址可达性通告，并将可达性类别与目的地址可达性的内部广告相关联。

公开(公告)号：US20100174947A1

公开(公告)日：2010-07-08

申请号：US12350518

申请日：2009-01-08

Applicant: James M. Caffrey ,  Karla K. Arndt ,  Aspen L. Payton ,  Keyur Patel ,  Robert L. Snyder

Inventor： James M. Caffrey ,  Karla K. Arndt ,  Aspen L. Payton ,  Keyur Patel ,  Robert L. Snyder

IPC: G06F11/30 ,  G06F11/07

CPC classification number: G06F11/0778 ,  G06F11/0721 ,  G06F11/0751 ,  G06F11/076

Abstract: A computer implemented method for a computer including a processor having a software stack accessed by multiple application programs includes receiving software requests from the multiple applications at the software stack; monitoring the rate of stack failures at the stack via a stack monitor; comparing the rate of stack failures with a time related threshold; and generating an alarm when the rate of stack failures exceeds the time related threshold.

Abstract translation: 一种用于计算机的计算机实现的方法，包括具有由多个应用程序访问的软件栈的处理器，包括从软件堆栈的多个应用接收软件请求; 通过堆栈监视器监视堆栈堆栈故障的速率; 将堆栈故障率与时间相关阈值进行比较; 并且当堆栈故障率超过时间相关阈值时产生报警。

公开(公告)号：US07668178B2

公开(公告)日：2010-02-23

申请号：US11214521

申请日：2005-08-30

Applicant: Luca Martini ,  Keyur Patel ,  W. Mark Townsley

Inventor： Luca Martini ,  Keyur Patel ,  W. Mark Townsley

IPC: H04L12/28

CPC classification number: H04L12/4691 ,  H04L12/4641 ,  H04L45/00 ,  H04L45/50

Abstract: Implementation of a VPN service such as a VPLS (Virtual Private Local area network Service) is performed utilizing a two-stage process. A first stage of the two-stage process involves providing notification of whether a PE (Provider Edge) router in a label-switching network has VPLS capability. Notification can include broadcasting a message from a PE router to remote PE routers in the label-switching network to indicate whether the broadcasting PE router is VPLS enabled. A second stage of the two-stage process involves, based on receiving a notification that a PE router is VPLS enabled, generating a query message to discover a set of VPLS instances to which the broadcasting PE router belongs. In this way, a given PE router generating the query message can identify other PE routers in the label-switching network associated with the same VPLS for purposes of setting up the VPLS in the label-switching network.

Abstract translation: 使用两阶段处理来执行诸如VPLS（虚拟专用局域网服务）之类的VPN服务的实现。 两级流程的第一阶段涉及提供标签交换网络中的PE（Provider Edge）路由器是否具有VPLS能力的通知。 通知可以包括从PE路由器向标签交换网络中的远程PE路由器广播消息，以指示广播PE路由器是否启用VPLS。 两级处理的第二阶段是基于接收到PE路由器启用VPLS的通知，生成查询消息以发现广播PE路由器所属的一组VPLS实例。 以这种方式，生成查询消息的给定PE路由器可以识别与相同VPLS相关联的标签交换网络中的其他PE路由器，以便在标签交换网络中建立VPLS。

公开(公告)号：US20090252745A1

公开(公告)日：2009-10-08

申请号：US11901324

申请日：2007-09-17

Applicant: Ravi R. Jhaveri ,  John G. McHutchison ,  Keyur Patel ,  Anna Mae Diehl

Inventor： Ravi R. Jhaveri ,  John G. McHutchison ,  Keyur Patel ,  Anna Mae Diehl

IPC: C12Q1/70 ,  C40B30/06 ,  A61K39/42

CPC classification number: C07K16/109 ,  C12Q1/6883 ,  C12Q1/707 ,  C12Q2600/136 ,  C12Q2600/156 ,  G01N33/5767 ,  G01N2800/085 ,  G01N2800/50

Abstract: The presently disclosed subject matter provides methods and compositions for predicting a tendency of a subject infected with hepatitis C virus (HCV) to develop steatosis. In some embodiments, the disclosed methods include the steps of (a) isolating from the subject a biological sample comprising an HCV Core polypeptide or a nucleic acid molecule encoding an HCV Core polypeptide; and (b) identifying the amino acids in the HCV Core polypeptide or encoded by the nucleic acid molecule in the biological sample corresponding to positions 182/186 of an HCV Core polypeptide amino acid sequence, whereby a tendency to develop steatosis in the subject is predicted when the amino acids corresponding to positions 182/186 of the HCV Core polypeptide amino acid sequence in the biological sample are either phenylalanine/valine or leucine/isoleucine. Also provided are compositions and methods for screening for candidate modulators of lipid accumulation in a subject as well as uses for the candidate modulators.

Abstract translation: 目前公开的主题提供了用于预测感染丙型肝炎病毒（HCV）的受试者发展为脂肪变性趋势的方法和组合物。 在一些实施方案中，所公开的方法包括以下步骤：（a）从受试者分离包含HCV核心多肽或编码HCV核心多肽的核酸分子的生物样品; 和（b）鉴定HCV核心多肽中的氨基酸或由对应于HCV核心多肽氨基酸序列的位置182/186的生物样品中的核酸分子编码的氨基酸，由此预测在受试者中发展脂肪变性的趋势 当对应于生物样品中HCV核心多肽氨基酸序列的位置182/186的氨基酸是苯丙氨酸/缬氨酸或亮氨酸/异亮氨酸时。 还提供了用于筛选受试者中脂质积聚的候选调节剂的组合物和方法以及候选调节剂的用途。

公开(公告)号：US07532631B2

公开(公告)日：2009-05-12

申请号：US11106414

申请日：2005-04-13

Applicant: Robert Raszuk ,  Rex E. Fernando ,  Himanshu Shah ,  Keyur Patel

Inventor： Robert Raszuk ,  Rex E. Fernando ,  Himanshu Shah ,  Keyur Patel

IPC: H04L12/56

CPC classification number: H04L45/28 ,  H04L45/02 ,  H04L45/04 ,  H04L45/54

Abstract: A method and apparatus are disclosed for accelerating Border Gateway Protocol (BGP) route convergence in an autonomous system. A virtual link identifier is assigned to each link of a set of communication links that are established between a BGP host and one or more network elements in one or more networks. For a particular link of the set of communication links, one or more routes that are reachable on the link are determined. The BGP host stores an association of the one or more routes with a BGP identifier of the BGP host and the virtual link identifier that is assigned to the particular link. The BGP host advertises the one or more routes to a BGP peer in a message, where the message includes the BGP identifier and the virtual link identifier.

Abstract translation: 公开了一种用于在自治系统中加速边界网关协议（BGP）路由收敛的方法和装置。 虚拟链路标识符被分配给在一个或多个网络中的BGP主机与一个或多个网络元件之间建立的一组通信链路的每个链路。 对于通信链路集合的特定链路，确定链路上可达到的一个或多个路由。 BGP主机存储一个或多个路由与BGP主机的BGP标识符和分配给特定链路的虚拟链路标识符的关联。 BGP主机向消息中的BGP对等体发布一条或多条路由，其中​​消息中包含BGP标识符和虚连接标识符。

公开(公告)号：US20090016365A1

公开(公告)日：2009-01-15

申请号：US11827772

申请日：2007-07-13

Applicant: Ali Sajassi ,  Keyur Patel ,  Chandrashekhar Appanna ,  Stefano Previdi

Inventor： Ali Sajassi ,  Keyur Patel ,  Chandrashekhar Appanna ,  Stefano Previdi

IPC: H04L12/66

CPC classification number: H04L45/745 ,  H04L45/02 ,  H04L45/04 ,  H04L45/50

Abstract: In one embodiment, a method includes receiving, by a first autonomous system border router (ASBR) of a first autonomous system (AS), a first plurality of provider-provisioned media access control (B-MAC) addresses via Interior Border Gateway Protocol (I-BGP). Each of first plurality of B-MAC addresses is associated with a provider edge (PE) device of the first AS. The first ASBR sends the first plurality of B-MAC addresses to a second ASBR of a second AS using Exterior Border Gateway Protocol (E-BGP). The first ASBR also receives via E-BGP a second plurality of B-MAC addresses each of which is associated with a PE device of the second AS. The first ASBR then distributes the second plurality of B-MAC addresses to each of the PE devices of the first AS using I-BGP.

Abstract translation: 在一个实施例中，一种方法包括由第一自治系统（AS）的第一自治系统边界路由器（ASBR）通过内部边界网关协议（第一自治系统（ASBR））接收第一多个提供者提供的媒体访问控制（B-MAC） I-BGP）。 第一多个B-MAC地址中的每一个与第一AS的提供商边缘（PE）设备相关联。 第一ASBR使用外部边界网关协议（E-BGP）向第二AS的第二ASBR发送第一多个B-MAC地址。 第一ASBR还经由E-BGP接收第二多个B-MAC地址，每个B-MAC地址与第二AS的PE设备相关联。 第一ASBR然后使用I-BGP将第二多个B-MAC地址分配给第一AS的每个PE设备。

公开(公告)号：US20080062986A1

公开(公告)日：2008-03-13

申请号：US11518383

申请日：2006-09-08

Applicant: Mike Shand ,  Stewart F. Bryant ,  David D. Ward ,  Gargi Nalawade ,  Keyur Patel ,  Clarence Filsfils ,  Stefano B. Previdi ,  Robert Raszuk

Inventor： Mike Shand ,  Stewart F. Bryant ,  David D. Ward ,  Gargi Nalawade ,  Keyur Patel ,  Clarence Filsfils ,  Stefano B. Previdi ,  Robert Raszuk

IPC: H04L12/56

CPC classification number: H04L45/22 ,  H04L45/02 ,  H04L45/04 ,  H04L45/28

Abstract: An apparatus for providing reachability in a routing domain of a data communications network having as components nodes and links therebetween for a routing domain—external destination address is described. The apparatus is arranged to advertise destination address reachability internally to nodes in the routing domain and associate a reachability category with said internal advertisement of said destination address reachability.

Abstract translation: 描述了一种用于在数据通信网络的路由域中提供可达性的装置，其具有用于路由域 - 外部目的地地址之间的节点和链路之间的组件。 该装置被布置为在内部向路由域中的节点通告目的地址可达性，并将可达性类别与所述目的地址可达性的所述内部广告相关联。

公开(公告)号：US20060291445A1

公开(公告)日：2006-12-28

申请号：US11152523

申请日：2005-06-14

Applicant: Luca Martini ,  Keyur Patel ,  Thomas Nadeau ,  James Guichard

Inventor： Luca Martini ,  Keyur Patel ,  Thomas Nadeau ,  James Guichard

IPC: H04L12/28

CPC classification number: H04L45/50 ,  H04L45/04

Abstract: A method and computer system for auto-routing of multi-hop pseudowires is presented. A first Provider Edge (PE) device receives an advertisement from a layer 2 (L2) capable network device, the advertisement including routing state for reaching the L2 device. A first Border Gateway Protocol (BGP) table is populated with the routing state for said L2 capable network device which is reachable by way of an address family reserved for L2 end point reachability information. The first PE device advertises the first BGP table information within a first Service Provider (SP) network such that a multi-hop Pseudowire is capable of being established which includes the L2 capable device.

Abstract translation: 提出了一种用于多跳伪线自动路由的方法和计算机系统。 第一提供商边缘（PE）设备从具有层2（L2）的网络设备接收广告，该广告包括到达L2设备的路由状态。 第一个边界网关协议（BGP）表填充有可通过为L2端点可达性信息保留的地址族可达的所述L2能力网络设备的路由状态。 第一PE设备在第一服务提供商（SP）网络内通告第一BGP表信息，使得能够建立包括L2能力设备的多跳伪线。