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公开(公告)号:US5389514A
公开(公告)日:1995-02-14
申请号:US937490
申请日:1992-08-28
申请人: John Taylor
发明人: John Taylor
CPC分类号: C07K14/005 , C12N15/102 , A61K48/00 , C12N2760/10122
摘要: A method is provided for specifically altering the nucleotide sequence of an RNA molecule. As performed in vitro the method comprises: (1) selecting a target sequence in an RNA molecule; (3) hybridizing the target sequence with a complementary nucleic acid, either DNA or RNA, thereby forming a double-stranded structure; (4) incubating the hybrid molecule with a cellular extract which contains components capable of specifically converting U to C in an RNA molecule, when the U is disposed within a double-stranded structure. Incubation of the hybrid molecule with cellular extracts comprising the RNA editing component results in a specific alteration of the nucleotide sequence of the RNA at the target sequence. The method of the invention may also be applied in vivo. Complementary nucleic acids are introduced into cells and hybridized to the target sequence to form a double-stranded structure. The RNA editing components already present in the cell may then specifically convert U to C in the target sequence resulting in an alteration in the target RNA molecule.
摘要翻译: 提供了用于特异性改变RNA分子的核苷酸序列的方法。 如在体外进行的,该方法包括:(1)选择RNA分子中的靶序列; (3)将靶序列与互补核酸,DNA或RNA杂交,从而形成双链结构; (4)当U配置在双链结构内时,将杂化分子与含有能够将RNA分子中的U特异性转化为C的成分的细胞提取物一起培养。 杂交分子与包含RNA编辑组分的细胞提取物的孵育导致目标序列中RNA的核苷酸序列的特异性改变。 本发明的方法也可以在体内应用。 将互补核酸引入细胞并与靶序列杂交以形成双链结构。 已经存在于细胞中的RNA编辑组分可以特异性地将U转化为靶序列中的C,导致靶RNA分子的改变。
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公开(公告)号:US5251426A
公开(公告)日:1993-10-12
申请号:US990399
申请日:1992-12-15
申请人: Rick Heisler , Ronald Heisler , John Taylor
发明人: Rick Heisler , Ronald Heisler , John Taylor
CPC分类号: B65B7/2807
摘要: An apparatus and method for the automatic on-demand conveying of stacks of nested lids to a lid placer employing two powered sections for first elevating the stacks of nested lids placed on a platform assembly then, shuttling the elevated nested stack interior of a guide assembly from a first position to a second position, the guide assembly then acts as an extension of the magazine of the lid placer until a predetermined quantity of lids have been separated and placed.
摘要翻译: 一种用于将嵌套盖的自动按需传送到盖子放置器的装置和方法,所述盖子采用两个动力部分,用于首先升高放置在平台组件上的嵌套盖子的堆叠,然后穿过引导组件的升高的嵌套堆叠内部 第一位置到第二位置时,引导组件然后用作盖子放置器的盒子的延伸部分,直到预定量的盖子被分离和放置。
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公开(公告)号:US5175798A
公开(公告)日:1992-12-29
申请号:US597827
申请日:1990-10-15
申请人: John Taylor , Denise Gorse , Trevor Clarkson
发明人: John Taylor , Denise Gorse , Trevor Clarkson
CPC分类号: G06N3/0472
摘要: A neuron for use in a neural processing network, comprises a memory having a plurality of storage locations at each of which a number representing a probability is stored, each of the storage locations being selectively addressable to cause the contents of the location to be read to an input of a comparator. A noise generator inputs to the comparator a random number representing noise. At an output of the comparator an output signal appears having a first or second value depending on the values of the numbers received from the addressed storage location and the noise generator, the probability of the output signal having a given one of the first and second values being determined by the number at the addressed location. Preferably the neuron receives from the environment signals representing success or failure of the network, the value of the number stored at the addressed location being changed in such a way as to increase the probability of the successful action if a success signal is received, and to decrease the probability of the unsuccessful action if a failure signal is received.
摘要翻译: 用于神经处理网络的神经元包括具有多个存储位置的存储器,每个存储位置存储代表概率的数字,每个存储位置可选地可寻址以使该位置的内容被读取到 比较器的输入。 噪声发生器向比较器输入表示噪声的随机数。 在比较器的输出端,根据从所寻址的存储位置和噪声发生器接收到的数字的值,出现具有第一或第二值的输出信号,输出信号具有第一和第二值中给定的一个的概率 由所处理位置的数量决定。 优选地,神经元从环境中接收到表示网络的成功或失败的信号,存储在寻址位置处的数量的值被改变,以便如果接收到成功信号则增加成功动作的概率,并且 如果接收到故障信号,则降低不成功的动作概率。
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公开(公告)号:US5153844A
公开(公告)日:1992-10-06
申请号:US469644
申请日:1990-01-23
申请人: Joseph A. Beni , Michael J. Merrill , Arun Prakash , John Taylor
发明人: Joseph A. Beni , Michael J. Merrill , Arun Prakash , John Taylor
IPC分类号: G01B11/30
CPC分类号: G01B11/306
摘要: This invention relates to a method and apparatus for determining the flatness or planarity of a surface and, specifically, to a method and apparatus for determining the flatness or planarity of a surface using a computerized optics technique.
摘要翻译: 本发明涉及一种用于确定表面的平坦度或平面度的方法和装置,具体地说,涉及使用计算机化光学技术确定表面的平坦度或平面度的方法和装置。
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公开(公告)号:US4825496A
公开(公告)日:1989-05-02
申请号:US178173
申请日:1988-04-06
申请人: John Taylor
发明人: John Taylor
CPC分类号: A47L11/40 , A47L1/08 , A47L11/185 , A47L11/4041 , A47L11/4069 , A47L11/4075 , A47L11/4088 , B08B1/04
摘要: A wheeled trolley (11,12) supports a removable back-pack unit (35,36) containing a motor drive (37,39) and a fluid pump (38). The motor (37) drives the pump (38) to draw fluid from a canister (32) and supply the fluid via flexible hoses (62,63, 64, 65) to a rotary brush unit (57,58,59). The motor rotates the brush via a flexible drive line (61) running from an output (39) on the back-pack to an input (56) on the brush handle (57). The trolley body (11) and back-pack casing (35) co-operate to retain the back-pack on the trolley in a readily removable manner. The canister (32) is likewise readily removable. The fluid supply and the motor electrical supply both run independently of the trolley. The back-pack can therefore be used as such, at locations remote from the trolley, or can remain on the trolley to function as a power pack for the apparatus. The brush (59) may be a cylindrical brush and two different formats (66,83) are disclosed.
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公开(公告)号:USD898291S1
公开(公告)日:2020-10-06
申请号:US29665511
申请日:2018-10-04
申请人: John Taylor , Fred Hein
设计人: John Taylor , Fred Hein
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公开(公告)号:US08801103B2
公开(公告)日:2014-08-12
申请号:US13447341
申请日:2012-04-16
申请人: D. Scott Bittinger , Vincent Audet , Ravi Hosalli , Johnathan Larner , Travis D. Bechtel , John Taylor
发明人: D. Scott Bittinger , Vincent Audet , Ravi Hosalli , Johnathan Larner , Travis D. Bechtel , John Taylor
CPC分类号: B60N2/874
摘要: An extendible and retractable head rest system for a motor vehicle seat has a head rest coupled to a linkage and an actuator coupled to the linkage. The linkage includes an offset drive link that upon the actuator being actuated to extend the head rest system to an operative position, the linkage moves the head rest up and forward and upon the actuator being actuated to retract the head rest system to an inoperative position, the linkage moves the head rest back and down. In an aspect, the linkage kneels when the head rest reaches an upper position to move the head rest to a forward position.
摘要翻译: 用于机动车辆座椅的可伸缩的头枕系统具有联接到联动装置的联接装置和连接到联动装置上的致动器的头枕。 该联动装置包括偏移驱动连杆,致动器被致动以将头枕系统延伸到操作位置,联动装置将头枕向上和向前移动,并且致动器被致动以将头枕系统缩回至不工作位置, 连杆使头枕上下移动。 在一方面,当头枕到达上部位置时,连杆机构跪下,以将头枕移动到向前的位置。
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公开(公告)号:US08188088B2
公开(公告)日:2012-05-29
申请号:US12304177
申请日:2007-06-14
IPC分类号: A61K31/497
CPC分类号: C07D231/14 , A01N43/36 , A01N43/56 , A01N43/647 , A01N43/78 , C07D207/34 , C07D249/04 , C07D277/56 , C07D403/12 , C07D417/12
摘要: Compounds of the formula (I), which are suitable for use as microbiocides, and in which A is A1, or A is A2, or A is A3, or A is A4 and B is a phenyl, naphthyl or quinolinyl group.
摘要翻译: 适用作杀微生物剂,其中A为A1或A为A2或A为A3的式(I)化合物为A,A为A4,B为苯基,萘基或喹啉基。
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公开(公告)号:US20110258696A1
公开(公告)日:2011-10-20
申请号:US13168789
申请日:2011-06-24
IPC分类号: G06F17/00
CPC分类号: H04L63/1441 , H04L63/1466 , H04W12/06 , H04W24/08 , H04W84/12
摘要: In one embodiment of the invention, a wireless network is adapted with a wireless network switch in communication with a plurality of access points, which are in communication with one or more stations. Coupled to the access points over an interconnect, the wireless network switch is adapted to receive a DEAUTHENTICATION message sent by one of the plurality of access points in the same coverage area of the station so as to detect the DEAUTHENTICATION message and to block communications between the plurality of access points and the station in response to determining that the DEAUTHENTICATION message is invalid.
摘要翻译: 在本发明的一个实施例中,无线网络适用于与与一个或多个站通信的多个接入点通信的无线网络交换机。 通过互连耦合到接入点,无线网络交换机适于接收由站的相同覆盖区域中的多个接入点之一发送的DEAUTHENTICATION消息,以便检测DEAUTHENTICATION消息并阻止 响应于确定DEAUTHENTICATION消息无效,多个接入点和站。
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公开(公告)号:US20100154624A1
公开(公告)日:2010-06-24
申请号:US12278113
申请日:2008-07-02
申请人: John Taylor , Raphael Joseph Francis Chetcuti , Charles Thomas Marshall , Colin Carson Mackenzie
发明人: John Taylor , Raphael Joseph Francis Chetcuti , Charles Thomas Marshall , Colin Carson Mackenzie
摘要: The following invention relates to a mount for holding a charge in a breech. The mount attaches, or is integral to, a charge and is provided with a dilation means which rests within a breech of a gun to prevent the charge from sliding back out of the breech when the gun is held at a high angle. The dilation means is fabricated from a material which, when the gun is fired, combusts to leave negligible debris in the breech.
摘要翻译: 本发明涉及一种用于在后膛中保持电荷的安装座。 安装件附接或与电荷成一体,并且设置有放置在枪的后膛中的扩张装置,以防止当枪保持高角度时电荷从后膛滑出。 扩张装置由一种材料制成,当枪被射出时,这种材料燃烧以在后膛中留下可忽略的碎片。
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