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    Thoracic impedance detection with blood resistivity compensation
    71.
    发明授权
    Thoracic impedance detection with blood resistivity compensation 有权
    胸部阻抗检测与血液电阻率补偿

    公开(公告)号：US07387610B2

    公开(公告)日：2008-06-17

    申请号：US10921503

    申请日：2004-08-19

    申请人： Jeffrey E. Stahmann ,  John Hatlestad ,  Boyce Moon

    发明人： Jeffrey E. Stahmann ,  John Hatlestad ,  Boyce Moon

    IPC分类号： A61B5/02

    CPC分类号： A61B5/053 ,  A61N1/3627 ,  A61N1/36521

    摘要： This document discusses, among other things, a cardiac rhythm management device or other implantable medical device that uses thoracic impedance to determine how much fluid is present in the thorax, such as for detecting or predicting congestive heart failure, pulmonary edema, pleural effusion, hypotension, or the like. The thoracic fluid amount determined from the thoracic impedance is compensated for changes in blood resistivity, which may result from changes in hematocrit level or other factors. The blood-resistivity-compensated thoracic fluid amount can be stored in the device or transmitted to an external device for storage or display. The blood-resistivity-compensated thoracic fluid amount can also be used to adjust a cardiac pacing, cardiac resynchronization, or other cardiac rhythm management or other therapy to the patient. This document also discusses applications of the devices and methods for predicting or indicating anemia.

    摘要翻译： 本文件尤其涉及一种使用胸部阻抗来确定胸部存在多少液体的心律管理装置或其他可植入医疗装置，例如用于检测或预测充血性心力衰竭，肺水肿，胸腔积液，低血压 ，等等。 根据胸部阻抗确定的胸腔液量补偿血液电阻率的变化，这可能是血细胞比容水平的变化或其他因素引起的。 血液电阻补偿的胸腔液量可以存储在设备中或者传输到外部设备进行存储或显示。 血液电阻补偿的胸液量也可用于调整心脏起搏，心脏再同步或其他心律控制或对患者的其他治疗。 本文件还讨论了用于预测或指示贫血的装置和方法的应用。

    System And Method For Determining Pulmonary Performance From Transthoracic Impedance Measures
    72.
    发明申请
    System And Method For Determining Pulmonary Performance From Transthoracic Impedance Measures 有权
    用于确定胸腔阻塞措施的肺功能的系统和方法

    公开(公告)号：US20080132802A1

    公开(公告)日：2008-06-05

    申请号：US12029422

    申请日：2008-02-11

    申请人： Quan Ni ,  Jesse W. Hartley ,  Kent Lee ,  Jeffrey E. Stahmann

    发明人： Quan Ni ,  Jesse W. Hartley ,  Kent Lee ,  Jeffrey E. Stahmann

    IPC分类号： A61B5/085

    CPC分类号： A61B5/0809 ,  A61B5/0002 ,  A61B5/0535 ,  A61N1/36521 ,  G06F19/3418

    摘要： A system and method for determining pulmonary performance from transthoracic impedance measures is provided. Transthoracic impedance measures collected by an implantable medical device are correlated to pulmonary functional measures. The pulmonary functional measures are grouped by respiratory pattern. Pulmonary performance is evaluated. Differences are determined by comparing the pulmonary functional measures for each respiratory pattern to the pulmonary functional measures for at least one previous respiratory pattern. A trend is identified from the differences. An alert is generated upon sufficient deviation of the trend from a threshold criteria.

    摘要翻译： 提供了一种通过经胸阻抗测量来确定肺功能的系统和方法。 由可植入医疗器械收集的经胸阻抗测量与肺功能测量相关。 肺功能测量按呼吸模式分组。 评估肺功能。 通过将每个呼吸模式的肺功能测量与至少一个之前的呼吸模式的肺功能测量进行比较来确定差异。 从差异中确定出一个趋势。 在趋势与阈值标准的充分偏差之后产生警报。

    Method and apparatus for maintaining synchronized pacing
    74.
    发明授权
    Method and apparatus for maintaining synchronized pacing 有权
    维持同步起搏的方法和装置

    公开(公告)号：US07379773B2

    公开(公告)日：2008-05-27

    申请号：US11085755

    申请日：2005-03-21

    申请人： Jeffrey E. Stahmann ,  Andrew P. Kramer

    发明人： Jeffrey E. Stahmann ,  Andrew P. Kramer

    IPC分类号： A61N1/00

    CPC分类号： A61N1/3627 ,  A61N1/368

    摘要： A device and method for cardiac rhythm management in which a cardiac site is paced in accordance with a pacing mode that employs sense signals from a different cardiac site. A protective period triggered by the sensing of intrinsic activity at the paced site is used to delay pacing by a protective delay interval without otherwise disturbing the pacing algorithm.

    摘要翻译： 心脏节律管理的装置和方法，其中心脏部位根据采用来自不同心脏部位的感测信号的起搏模式而起搏。 通过感觉起搏部位的内在活动触发的保护期用于延迟起搏保护延迟时间间隔，而不会影响起搏算法。

    Therapy control based on the rate of change of intracardiac impedance
    75.
    发明授权
    Therapy control based on the rate of change of intracardiac impedance 有权
    基于心内阻抗变化率的治疗控制

    公开(公告)号：US07376463B2

    公开(公告)日：2008-05-20

    申请号：US11169339

    申请日：2005-06-29

    申请人： Rodney W. Salo ,  Joseph M. Pastore ,  Jeffrey E. Stahmann ,  Jesse W. Hartley

    发明人： Rodney W. Salo ,  Joseph M. Pastore ,  Jeffrey E. Stahmann ,  Jesse W. Hartley

    IPC分类号： A61N1/00

    CPC分类号： A61N1/36521 ,  A61N1/30

    摘要： A system comprising a medical device that includes an impedance measurement circuit adapted to be coupled to implantable electrodes to obtain an intracardiac impedance signal between electrodes, a therapy circuit operable to deliver a therapy to a subject, and a controller circuit coupled to the impedance measurement circuit and the therapy circuit. The controller circuit determines a time rate of change of the intracardiac impedance signal and adjusts at least one parameter related to therapy in a manner that alters the rate of change.

    摘要翻译： 一种包括医疗装置的系统，该医疗装置包括阻抗测量电路，该阻抗测量电路适于耦合到可植入电极以获得电极之间的心内阻抗信号，可操作以将治疗递送给受试者的治疗电路，以及耦合到所述阻抗测量电路 和治疗电路。 控制器电路确定心内阻抗信号的时间变化率，并且以改变变化率的方式调节与治疗相关的至少一个参数。

    System and method for timing synchronized pacing
    77.
    发明授权
    System and method for timing synchronized pacing 有权
    定时同步起搏的系统和方法

    公开(公告)号：US07158828B2

    公开(公告)日：2007-01-02

    申请号：US10454014

    申请日：2003-06-03

    申请人： Andrew P. Kramer ,  Jeffrey E. Stahmann

    发明人： Andrew P. Kramer ,  Jeffrey E. Stahmann

    IPC分类号： A61N1/368

    CPC分类号： A61N1/3627 ,  A61N1/3684

    摘要： A device and method for cardiac rhythm management in which a heart chamber is paced in accordance with sense signals from the opposite chamber or other distant cardiac site. The method is particularly useful in delivering cardiac resynchronization therapy.

    摘要翻译： 一种用于心律控制的装置和方法，其中根据来自相对室或其他远端心脏位点的感测信号来起搏心室。 该方法在递送心脏再同步治疗中特别有用。

    System and method for cardiac rhythm management with dynamically adjusted synchronized chamber pacing protection period
    79.
    发明授权
    System and method for cardiac rhythm management with dynamically adjusted synchronized chamber pacing protection period 有权
    动态调节同步腔起搏保护期的心律管理系统和方法

    公开(公告)号：US07003347B2

    公开(公告)日：2006-02-21

    申请号：US10172380

    申请日：2002-06-14

    申请人： Jeffrey E. Stahmann

    发明人： Jeffrey E. Stahmann

    IPC分类号： A61N1/368

    CPC分类号： A61N1/3627 ,  A61N1/3684

    摘要： A device and method for cardiac rhythm management in which one heart chamber, designated as the synchronized chamber, is paced in accordance with a pacing mode that employs sense signals from the opposite chamber, designated as the rate chamber. A synchronized chamber protection period triggered by an intrinsic or paced beat in the synchronized chamber is used to inhibit pacing without otherwise disturbing the pacing algorithm. The duration of the synchronized chamber protection period is dynamically adjusted based upon detection of a repolarization in the synchronized chamber

    摘要翻译： 一种用于心律管理的装置和方法，其中指定为同步腔的一个心脏室根据起搏模式进行起搏，该起搏模式采用来自相对室的指定为速率室的感测信号。 由同步室中的固有或起搏的搏动触发的同步室保护期限用于抑制起搏而不影响起搏算法。 基于同步室中的复极度的检测来动态地调整同步室保护期的持续时间。