公开(公告)号：US06811805B2

公开(公告)日：2004-11-02

申请号：US10154249

申请日：2002-05-22

申请人： Allen Gilliard ,  Lynn Cook Winterton ,  Rafael Victor Andino ,  John Lally

发明人： Allen Gilliard ,  Lynn Cook Winterton ,  Rafael Victor Andino ,  John Lally

IPC分类号： A61L5103

CPC分类号： B29D11/00317 ,  B29D11/00903 ,  G02B1/10

摘要： The invention provide a method for applying a coating to an ophthalmic lens or a mold for making the ophthalmic lens or a medical device other than ophthalmic lens. The method comprises spraying at least one layer of a coating liquid onto an ophthalmic lens using a spraying process selected from the group consisting of an air-assisted atomization and dispensing process, an ultrasonic-assisted atomization and dispensing process, a piezoelectric assisted atomization and dispensing process, an electro-mechanical jet printing process, a piezo-electric jet printing process, a piezo-electric with hydrostatic pressure jet printing process, and a thermal jet printing process. The coating can comprise a property/functionality pattern or a color image or combination of both.

摘要翻译： 本发明提供了一种将涂层施加到眼用透镜或用于制造眼科镜片或除眼镜之外的医疗装置的模具的方法。 该方法包括使用选自空气辅助雾化和分配过程，超声波辅助雾化和分配过程，压电辅助雾化和分配过程的喷雾方法将至少一层涂布液体喷涂到眼科镜片上 工艺，机电喷射印刷工艺，压电喷墨印刷工艺，静压喷射印刷工艺的压电和热喷涂印刷工艺。 涂层可以包括性质/功能性图案或彩色图像或两者的组合。

公开(公告)号：US06589665B2

公开(公告)日：2003-07-08

申请号：US09867827

申请日：2001-05-30

申请人： Peter Chabrecek ,  Dieter Lohmann ,  Jörg Leukel ,  Lynn Cook Winterton ,  Yongxing Qiu ,  John Martin Lally

发明人： Peter Chabrecek ,  Dieter Lohmann ,  Jörg Leukel ,  Lynn Cook Winterton ,  Yongxing Qiu ,  John Martin Lally

IPC分类号： G02B104

CPC分类号： C08J7/16 ,  A61L27/34 ,  G02B1/043 ,  Y10T428/21 ,  Y10T428/31855 ,  Y10T428/31909 ,  Y10T428/31928 ,  Y10T428/31935

摘要： The invention relates to novel composite materials comprising (a) an inorganic or organic bulk material having attached to its surface at least one polyionic material that comprises covalently bound initiator moieties for radical polymerization; and (b) a hydrophilic surface coating obtainable by applying one or more different ethylenically unsaturated hydrophilic monomers or macromonomers to the bulk material surface provided with the initiator radicals and polymerizing said monomers or macromonomers. The composite materials of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus useful for the manufacture of biomedical articles such as ophthalmic devices.

摘要翻译： 本发明涉及新颖的复合材料，其包括（a）无机或有机本体材料，其在其表面附着至少一种聚离子材料，其包含共价结合的用于自由基聚合的引发剂部分; 和（b）可通过将一种或多种不同的烯属不饱和亲水单体或大分子单体施用于提供有引发剂基团的本体材料表面并聚合所述单体或大分子单体而获得的亲水性表面涂层。本发明的复合材料具有关于粘附 底物，耐久性，亲水性，润湿性，生物相容性和渗透性，因此可用于制造生物医学制品如眼科装置。

公开(公告)号：US06451871B1

公开(公告)日：2002-09-17

申请号：US09559945

申请日：2000-04-27

申请人： Lynn Cook Winterton ,  Juergen Vogt ,  John Martin Lally ,  Friedrich Stockinger

发明人： Lynn Cook Winterton ,  Juergen Vogt ,  John Martin Lally ,  Friedrich Stockinger

IPC分类号： G02C704

CPC分类号： G02B1/043 ,  C08J7/047 ,  G02B1/10

摘要： Biomedical devices, such as ophthalmic lenses, and methods of making such devices having a surface coating including at least one polyionic layer. A preferred method involves spray coating a polycationic material onto a core lens, rinsing and drying the lens, followed by spray coating a polyanionic material, rinsing and drying. The coating process may be applied a plurality of times to achieve a multi-layer coating on the lens surface. A particularly preferred embodiment is a contact lens comprising a highly oxygen permeable hydrophobic core coated with a 5 to 20 bilayers of hydrophilic polyionic materials.

摘要翻译： 生物医学装置，如眼科镜片，以及制造具有包括至少一个聚离子层的表面涂层的装置的方法。 优选的方法包括将聚阳离子材料喷涂到芯晶片上，漂洗和干燥晶状体，然后喷涂聚阴离子材料，冲洗和干燥。 涂覆过程可以多次施加以在透镜表面上实现多层涂层。 特别优选的实施方案是包含涂覆有5至20双亲水性聚离子材料的高透氧性疏水核心的隐形眼镜。