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1.发明公开公开(公告)号：US20240325597A1
公开(公告)日：2024-10-03
申请号：US18426780
申请日：2024-01-30
Applicant: Johnson & Johnson Vision Care, Inc.
Inventor： Michael F. Widman , Ghulam Maharvi
IPC: A61L27/16 , A61L27/52 , C08F2/50 , C08F283/12 , C08K5/5397 , G02B1/04
CPC classification number: A61L27/16 , A61L27/52 , C08F2/50 , C08F283/126 , C08K5/5397 , G02B1/043 , A61L2430/16 , C08F2438/00
Abstract: Disclosed are ophthalmic devices formed by a process comprising: (a) providing a reactive composition containing: (i) a polymerization initiator that is capable, upon a first activation, of forming two or more free radical groups, at least one of which is further activatable by subsequent activation; (ii) one or more ethylenically unsaturated compounds; and (iii) a crosslinker; (b) subjecting the reactive composition to a first activation step such that the reactive composition polymerizes therein to form a crosslinked substrate network containing a covalently bound activatable free radical initiator; (c) deactivating at least a portion of the covalently bound activatable free radical initiator at one or more selective regions of the crosslinked substrate network such that the crosslinked substrate network contains retained covalently bound activatable free radical initiator outside of the one or more selective regions and optionally within the one or more selective regions; (d) contacting the crosslinked substrate network with a grafting composition containing one or more ethylenically unsaturated compounds, wherein the contacting is conducted under conditions such that the grafting composition penetrates into the crosslinked substrate network; and (e) activating the retained covalently bound activatable free radical initiator such that the grafting composition polymerizes with the crosslinked substrate network, thereby forming grafted polymeric networks, outside of the selective regions and optionally partially within the selective regions.
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公开(公告)号：US12102200B2
公开(公告)日：2024-10-01
申请号：US17030736
申请日：2020-09-24
Applicant: TWENTY TWENTY THERAPEUTICS LLC
Inventor： Daniel Otts , Stein Kuiper
CPC classification number: A45C11/005 , C11D3/0078 , G02B1/043 , G02C7/085 , G02C2202/18
Abstract: Systems and kits for replenishing an electrowetting ophthalmic device are described. In an embodiment, the system includes an electrowetting ophthalmic device including a lens material defining a cavity encasing an aqueous electrowetting solution; a replenishing solution having an osmolarity approximately equal to an osmolarity of the aqueous electrowetting solution; and a container shaped to carry the electrowetting ophthalmic device and the replenishing solution and to position the electrowetting ophthalmic device in contact with the replenishing solution when the electrowetting ophthalmic device and the replenishing solution are carried by the container. In an embodiment, the osmolarity of the aqueous electrowetting solution is higher than an osmolarity of a tear fluid of an eye.
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公开(公告)号：US20240319523A1
公开(公告)日：2024-09-26
申请号：US18578876
申请日：2022-07-13
Applicant: LEONARDO VISION S.R.L.
Inventor： Leonardo PESI
CPC classification number: G02C11/10 , A61B5/6821 , G02B1/043
Abstract: Contact lens made of non-hydrophilized material and including at least one functional element disposed in correspondence with a rear concave surface of the lens which is facing, during use, toward the eyeball.
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公开(公告)号：US20240288711A1
公开(公告)日：2024-08-29
申请号：US18287258
申请日：2022-03-28
Applicant: NATIONAL INSTITUTE FOR MATERIALS SCIENCE , SEED CO., LTD.
Inventor： Izumi ICHINOSE , Kunio JONIN , Risako YAMANAKA
Abstract: An objective of the present invention is to provide a method for manufacturing a soft ocular lens in which the surface of the lens is hydrophilized by means of plasma processing, wherein a substrate surface can be sufficiently hydrophilized by performing, once, a reaction between the substrate and a hydrophilic polymer. Another object of the present invention is to provide a soft ocular lens with sufficient hydrophilicity which comprises only one layer comprising a hydrophilic polymer on a substrate surface. A substrate comprising a hydrocarbon group-containing polysiloxane is subjected to plasma processing with an inert gas such as nitrogen, to form a radical including Si—CH2 on the substrate surface, and produce radical rearrangement with a hydrophilic polymer, thereby causing the hydrophilic polymer to bind to the substrate surface by recombination of a radical generated in the hydrophilic polymer with the substrate.
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公开(公告)号：US12071529B2
公开(公告)日：2024-08-27
申请号：US18086741
申请日：2022-12-22
Applicant: Khalifa University of Science and Technology
Inventor： Haider Butt , Ahmed E. Salih
CPC classification number: C08K3/08 , B29D11/00125 , G02B1/043 , C08K2003/0806 , C08K2201/003 , C08K2201/011 , C08K2201/013
Abstract: A method of incorporating nanoparticles into a contact lens includes contacting the contact lens with a solvent sufficient to remove liquid from the contact lens and contacting the contact lens with colloidal nanoparticles sufficient to transfer nanoparticles from the colloidal nanoparticles to the contact lens.
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Patent Agency Ranking
公开(公告)号：US12038556B2
公开(公告)日：2024-07-16
申请号：US18224082
申请日：2023-07-20
Applicant: CooperVision International Limited
Inventor： Inna Maltseva , Nancy J. Keir , Andrew Luk , Victoria Rogers
IPC: G02B1/04 , A45C11/00 , A61K9/00 , A61K31/355 , C08J3/075 , C08K5/1545
CPC classification number: G02B1/043 , A45C11/005 , A61K9/0051 , A61K31/355 , C08J3/075 , C08K5/1545 , C08J2333/26 , C08J2383/04
Abstract: A contact lens having antioxidant properties is described as well as methods of manufacturing the same. The contact lens can be present in a sealed contact lens package. The seal contact lens package can include at least a) a plastic base member having a cavity; b) a contact lens packaging solution in the cavity; c) a sterile, unworn contact lens immersed in the contact lens packaging solution in the cavity; and d) a cover that forms a liquid-tight seal with the plastic base member. As an example, the unworn contact lens is a silicone hydrogel contact lens having present therein vitamin E. The vitamin E is non-releasable from the unworn contact lens and the contact lens packaging solution has less than 1 ppm of vitamin E present. The vitamin E is trapped, embedded, absorbed, or non-covalently attached in the unworn contact lens.
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公开(公告)号：US12024597B2
公开(公告)日：2024-07-02
申请号：US18114570
申请日：2023-02-27
Applicant: Clearlab SG Pte Ltd.
Inventor： Jong Gu Park , Yeong Shenq Chow , John Christopher Phelan
IPC: C08G77/46 , A61L26/00 , C08F293/00 , C08L53/00 , G02B1/04
CPC classification number: C08G77/46 , A61L26/0019 , A61L26/0066 , A61L26/008 , C08F293/00 , C08L53/005 , G02B1/043 , A61L2300/404 , C08G2210/00 , C08L2201/10 , C08L2203/02
Abstract: Described herein are wound dressing comprising a silicone hydrogel composition and optionally an antimicrobial agent, and methods of making and use thereof. The silicone hydrogel compositions comprise an actinically-crosslinkable polysiloxane-polyglycerol block copolymer crosslinked with a crosslinker. The actinically-crosslinkable polysiloxane-polyglycerol block copolymer being derived from: a polysiloxane prepolymer comprising a polyglycerol side chain, the polyglycerol side chain comprising an ethylenically unsaturated group covalently linked thereto, wherein the ethylenically unsaturated group is actinically curable.
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公开(公告)号：US20240209179A1
公开(公告)日：2024-06-27
申请号：US18086741
申请日：2022-12-22
Applicant: Khalifa University of Science and Technology
Inventor： Haider BUTT , Ahmed E. SALIH
CPC classification number: C08K3/08 , B29D11/00125 , G02B1/043 , C08K2003/0806 , C08K2201/003 , C08K2201/011 , C08K2201/013
Abstract: A method of incorporating nanoparticles into a contact lens includes contacting the contact lens with a solvent sufficient to remove liquid from the contact lens and contacting the contact lens with colloidal nanoparticles sufficient to transfer nanoparticles from the colloidal nanoparticles to the contact lens.
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公开(公告)号：US20240184137A1
公开(公告)日：2024-06-06
申请号：US18285518
申请日：2022-04-12
Inventor： Anuj CHAUHAN , Poorvajan SEKAR
Abstract: Aspects of the present disclosure provides for contact lenses that employing Vitamin-E integrated contact lenses as a vehicle for treating conditions (e.g., bacterial keratitis and post-surgical inflammation) through at least one medicament delivery (e.g., a triumvirate medicament delivery such as a triplicate of antibiotic and anti-inflammatory drugs) to the ocular surface.
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公开(公告)号：US11993037B1
公开(公告)日：2024-05-28
申请号：US17552536
申请日：2021-12-16
Applicant: Johnson & Johnson Vision Care, Inc.
Inventor： Shivkumar Mahadevan , Dawn D. Wright , Patricia Martin , Jie Xu , John R. Buch
CPC classification number: B29D11/00038 , G02B1/043 , G02C7/049
Abstract: A method or use of a contact lens, includes applying to at least one eye of a contact lens wearer the contact lens that is a free radical reaction product of a reactive mixture that includes one or more polymerizable compounds suitable for making the contact lens; and a high energy visible (HEV) light absorbing compound; and improving, by the contact lens, at least one clinical attribute comprising overall preference of the contact lens while using computer screens and digital devices as observed by the contact lens wearer, comfort at the end of the day, CLUE Comfort score, CLUE Vision score.
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