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公开(公告)号：US20090043110A1
公开(公告)日：2009-02-12
申请号：US12087092
申请日：2006-12-26
IPC分类号： C07D209/44
CPC分类号： C07B53/00 , C07D209/44
摘要： The present invention is to provide a novel method for producing (2S)-2-benzyl-3-(cis-hexahydro-2-isoindolinylcarbonyl)propionic acid which is useful as a therapeutic agent for diabetes. The present invention relates to a method for producing (2S)-2-benzyl-3-(cis-hexahydro-2-isoindolinylcarbonyl)propionic acid, which is characterized in that 2-benzylidene-3-(cis-hexahydro-2-isoindolinylcarbonyl)propionic acid is subjected to a catalytic reduction reaction in the presence of an asymmetric catalyst prepared from a pyrrolidinebisphosphine compound (I) represented by the following general formula (I): wherein, R1 represents a linear or branched alkyl group having 1-10 carbon atoms, cycloalkyl group, aralkyl group or aryl group which may respectively have a substituent; and R2 and R3 independently represent an optionally substituted aryl group. The * mark in the pyrrolidine ring shows that the carbon atom at that position has the S configuration, and a rhodium compound.
摘要翻译： 本发明提供可用作糖尿病治疗剂的（2S）-2-苄基-3-（顺式 - 六氢-2-异吲哚基羰基）丙酸的新方法。 本发明涉及（2S）-2-苄基-3-（顺 - 六氢-2-异二氢吲哚基羰基）丙酸的制备方法，其特征在于2-亚苄基-3-（顺式 - 六氢-2-异吲哚基羰基） ）丙酸在由以下通式（I）表示的吡咯烷二膦化合物（I）制备的不对称催化剂存在下进行催化还原反应：其中，R1表示具有1-10个碳原子的直链或支链烷基 原子，环烷基，芳烷基或可分别具有取代基的芳基; 并且R 2和R 3独立地表示任选取代的芳基。 吡咯烷环中的*标记表示该位置的碳原子具有S构型和铑化合物。
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公开(公告)号：US20080252294A1
公开(公告)日：2008-10-16
申请号：US11980579
申请日：2007-10-31
IPC分类号： G01R33/3815
CPC分类号： G01R33/34069 , G01R33/34007 , G01R33/34023 , G01R33/34053 , G01R33/3806 , G01R33/56536
摘要： It is an object of the invention to provide, in a nuclear magnetic resonance spectrometer wherein the direction of the static magnetic field is the horizontal direction, a nuclear magnetic resonance probe coil having a highly uniform magnetic field, which can measure at high sensitivity. The present invention, by selecting the design and shapes of the materials forming the probe coil with a view to suppressing disorder in the magnetic field distribution, and using superconducting thin film coils formed on hollow circular substrates to form a receiver coil and coil support materials having curved surfaces, provides a nuclear magnetic resonance spectrometer of high sensitivity that can improve uniformity of a magnetic field.
摘要翻译： 本发明的目的是提供一种核磁共振光谱仪，其中静磁场的方向为水平方向，具有高度均匀的磁场的核磁共振探针线圈，其能够以高灵敏度测量。 本发明通过选择形成探针线圈的材料的设计和形状，以抑制磁场分布的紊乱，并且使用形成在中空圆形基板上的超导薄膜线圈，以形成具有 提供了高灵敏度的核磁共振光谱仪，可以提高磁场的均匀性。
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公开(公告)号：US20080111548A1
公开(公告)日：2008-05-15
申请号：US11936820
申请日：2007-11-08
IPC分类号： G01R33/32
CPC分类号： G01R33/30 , G01R33/34023 , G01R33/34046 , G01R33/34053 , G01R33/34069 , G01R33/34092 , G01R33/3628 , G01R33/3635
摘要： A signal line is drawn from a generally middle point of the antenna coil, and a capacitance-variable capacitors are connected at both sides of the antenna coil. This structure realizes a circuit in which a series resonance circuit composed of an antenna coil and a capacitor and an another series resonance circuit composed of an another antenna coil and an another capacitor are connected in parallel to each other across the generally middle point of the antenna coil to which the signal line is connected. Through the control of the resonance frequencies of the series resonance circuits, the parallel resonance frequency of the whole antenna is tuned to a desired frequency, and the resonance characteristic in which the impedance is matched to a specific value, e.g., 50 Ω, can be achieved.
摘要翻译： 信号线从天线线圈的大致中点抽出，电容可变电容器连接在天线线圈的两侧。 这种结构实现了一种电路，其中由天线线圈和电容器组成的串联谐振电路和由另一个天线线圈和另一个电容器组成的另一个串联谐振电路在天线的大致中间点处彼此并联连接 线圈连接到信号线。 通过控制串联谐振电路的谐振频率，将整个天线的并联谐振频率调谐到期望的频率，并且阻抗匹配到特定值（例如50Ω）的谐振特性可以是 实现了
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公开(公告)号：US20080061786A1
公开(公告)日：2008-03-13
申请号：US11757453
申请日：2007-06-04
申请人： YUZO FUKUDA , Kazuo Saitoh , Hiroyuki Yamamoto , Michiya Okada
发明人： YUZO FUKUDA , Kazuo Saitoh , Hiroyuki Yamamoto , Michiya Okada
IPC分类号： G01R33/32
CPC分类号： G01R33/3657 , G01R33/34023 , G01R33/34053 , G01R33/34069
摘要： A probe for a nuclear magnetic resonance apparatus comprises: a transmission coil for irradiating a sample with a high-frequency electromagnetic wave; and a receiving coil for detecting a nuclear magnetic resonance signal emitted by the sample, wherein a selector switch is disposed to the transmission coil to reduce the deterioration of sensitivity of the receiving coil by switching the resonance state of the transmission circuit between during irradiation and during detection, even if an electromagnetic coupling remains between transmission and reception.
摘要翻译： 核磁共振装置的探针包括：用高频电磁波照射样品的发射线圈; 以及用于检测样品发射的核磁共振信号的接收线圈，其中选择器开关设置在传输线圈上，以通过在照射期间和之前切换传输电路的谐振状态来减少接收线圈的灵敏度的劣化 检测，即使电磁耦合保持在发送和接收之间。
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公开(公告)号：US07298384B2
公开(公告)日：2007-11-20
申请号：US10341423
申请日：2003-01-14
申请人： Mahoro Anabuki , Hiroyuki Yamamoto
发明人： Mahoro Anabuki , Hiroyuki Yamamoto
IPC分类号： G09G5/00
CPC分类号： G02B27/017 , G02B2027/0187 , G02B2027/0198
摘要： A mixed reality presenting apparatus for merging an incident real-space image and a generated virtual-space image comprises a measuring section which measures the orientation of a unit for entering the real-space image and the speed or acceleration thereof; a virtual-space image generating section which generates virtual-space image data on the basis of the measurement result; a correcting optical system which corrects the path of light passing therethrough; and a correcting optical system control section which controls the correcting optical system on the basis of the measured speed or acceleration.
摘要翻译： 用于合并事件实时空间图像和生成的虚拟空间图像的混合现实呈现装置包括：测量部分，其测量用于输入实际空间图像的单元的方向及其速度或加速度; 虚拟空间图像生成部，其基于测定结果生成虚拟空间图像数据; 校正光学系统，其校正穿过其中的光的路径; 以及校正光学系统控制部，其基于测量的速度或加速度来控制校正光学系统。
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公开(公告)号：US07138801B2
公开(公告)日：2006-11-21
申请号：US11192081
申请日：2005-07-29
IPC分类号： G01V3/00
CPC分类号： G01R33/34053 , G01R33/34007 , G01R33/34023 , G01R33/34069 , G01R33/34092 , H01F5/003 , H01F6/00 , H01F6/06 , H01F17/0013
摘要： An NMR probe having a high-sensitivity solenoid probe coil for receiving free induction decay (FID) signals in nuclear magnetic resonance (NMR) spectroscopy, and an NMR spectrometer which incorporates this probe. The solenoid probe coil is fabricated by a building block approach where it mainly consists of coil substrates having superconducting thin film coils made from superconducting thin film thereon, and side holding plates and a wiring substrate with line pattern of superconducting thin films which are both perpendicular to the coil substrates. The superconducting thin film coils are connected with the line patterns of superconducting thin films by capacitive coupling to make the solenoid coil configuration and solenoid probe coil of superconducting material.
摘要翻译： 具有用于在核磁共振（NMR）光谱中接受自由感应衰减（FID）信号的高灵敏度电磁探针线圈的NMR探针和包含该探针的NMR光谱仪。 螺线管探针线圈由构建块方法制造，其主要由其上由超导薄膜制成的超导薄膜线圈的线圈基板和具有垂直于超导薄膜的线路图案的侧保持板和布线基板组成 线圈基板。 超导薄膜线圈通过电容耦合与超导薄膜的线路图案连接，以形成电磁线圈配置和超导材料的螺线管探针线圈。
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公开(公告)号：US20060233564A1
公开(公告)日：2006-10-19
申请号：US11181232
申请日：2005-07-14
申请人： Hiroyuki Yamamoto
发明人： Hiroyuki Yamamoto
IPC分类号： G03G15/00
CPC分类号： H04N1/00904 , G03G15/5004 , H04N1/00885 , H04N1/32609 , H04N1/3263 , H04N1/32683 , H04N2201/0081 , H04N2201/0093
摘要： There is described an image reading apparatus, which employs the electric double layer. The image reading apparatus includes: an electric power source; an analogue image signal generating section that is coupled to the electric power source through a power line and converts an optical image to analogue image signals; an electric double layer capacitor that is coupled to the power line; a first switch that is coupled to both the electric power source and the electric double layer capacitor, in such a manner that the first switch is inserted between them; and a controlling section to control the first switch so as to make the first switch open in response to a output request signal for requesting an outputting operation of the analogue image signals.
摘要翻译： 描述了一种使用双电层的图像读取装置。 图像读取装置包括：电源; 模拟图像信号产生部分，其通过电力线耦合到电源并将光学图像转换成模拟图像信号; 耦合到电力线的双电层电容器; 第一开关，其以这样的方式耦合到电源和双电层电容器，使得第一开关插入它们之间; 以及控制部分，用于控制第一开关，以便响应于用于请求模拟图像信号的输出操作的输出请求信号使第一开关断开。
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公开(公告)号：US20060033498A1
公开(公告)日：2006-02-16
申请号：US11196279
申请日：2005-08-04
申请人： Kazuo Saitoh , Haruhiro Hasegawa , Hiroyuki Yamamoto , Hisaaki Ochi , Tsuyoshi Wakuda , Michiya Okada
发明人： Kazuo Saitoh , Haruhiro Hasegawa , Hiroyuki Yamamoto , Hisaaki Ochi , Tsuyoshi Wakuda , Michiya Okada
IPC分类号： G01V3/00
CPC分类号： G01R33/34053 , G01R33/34007 , G01R33/34023 , G01R33/34069 , G01R33/34092
摘要： A configuration of an NMR apparatus is provided. In the NMR apparatus, a magnetic field space of higher uniformity is generated by split superconducting magnets. At the same time, it is provided with a cryo probe excellent in cooling capability and sensitivity between two superconducting solenoid coils constructed in very close proximity to each other. For this purpose, a probe coil provided between the two superconducting solenoid coils is so constructed that the following is implemented: a certain distance is ensured between a substrate with a coil formed thereon and another, and the substrates and spacer substrates for cooling are alternately laminated. The spacer substrates are cooled by a cold head of sapphire. When the probe coil is inserted in the same direction as a sample tube (direction perpendicular to the static magnetic field), the spacer substrates cannot be coupled directly by the cold head of sapphire. Therefore, they are cooled through a fixed substrate for thermal conduction of sapphire coupled with the cold head.
摘要翻译： 提供了NMR装置的结构。 在NMR装置中，通过分体超导磁体产生更高均匀性的磁场空间。 同时，它提供了一种低温探针，该低温探针具有非常接近的两个超导螺线管线圈之间的冷却能力和灵敏度。 为此，设置在两个超导螺线管线圈之间的探针线圈被构造成使得实现以下功能：在其上形成有线圈的基板和另一个之间确保一定距离，并且用于冷却的基板和间隔基板交替层压 。 间隔基板被蓝宝石的冷头冷却。 当探针线圈沿着与样品管相同的方向（垂直于静磁场的方向）插入时，间隔基板不能由蓝宝石的冷头直接耦合。 因此，它们通过固定的基板进行冷却，用于与冷头连接的蓝宝石的热传导。
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79.发明授权公开(公告)号：US06941118B2
公开(公告)日：2005-09-06
申请号：US10125592
申请日：2002-04-19
申请人： Hiroyuki Yamamoto
发明人： Hiroyuki Yamamoto
CPC分类号： H03F1/34 , H03C3/406 , H03F1/3294 , H03F2200/57
摘要： A negative feedback amplifier has input portions for receiving input signals, adder circuits, a quadrature modulator for performing a quadrature modulation on outputs of the adder circuits, a first signal level variable control circuit for adjusting a level of an output signal from the quadrature modulator, an amplifier circuit for amplifying an output of the first signal level variable control circuit, a feedback circuit for negative feedbacking an output of the negative feedback circuit to the adder circuit, and a second control circuit for controlling an adjusting amount in the first signal level variable control circuit based on the output signal levels of the adder circuits so that the output signal levels of the adder circuits becomes predetermined values. The feedback circuit includes a first control circuit for controlling a signal level of the feedback circuit so that the output signal level of the amplifier circuit becomes a predetermined value.
摘要翻译： 负反馈放大器具有用于接收输入信号的输入部分，加法器电路，用于对加法器电路的输出执行正交调制的正交调制器，用于调整来自正交调制器的输出信号电平的第一信号电平可变控制电路， 用于放大第一信号电平可变控制电路的输出的放大器电路，用于将负反馈电路的输出负反馈到加法器电路的反馈电路，以及用于控制第一信号电平变量中的调整量的第二控制电路 基于加法器电路的输出信号电平的控制电路，使得加法器电路的输出信号电平变为预定值。 反馈电路包括用于控制反馈电路的信号电平的第一控制电路，使得放大器电路的输出信号电平变为预定值。
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公开(公告)号：US06933039B2
公开(公告)日：2005-08-23
申请号：US10142451
申请日：2002-05-10
申请人： Hiroyuki Yamamoto
发明人： Hiroyuki Yamamoto
IPC分类号： G02B5/00 , C09D165/04 , C09D169/00 , C09D179/08 , G02B5/04 , G02B5/08 , G02B5/30 , G11B7/00 , G02B7/18
CPC分类号： C09D169/00 , C09D165/04 , C09D179/08 , G11B7/00 , Y10T428/24802 , Y10T428/31504 , Y10T428/31507 , Y10T428/31721
摘要： An optical component comprising a substrate and a transparent polymer coating film laminated thereon, said polymer coating film including: (1) a processed surface formed into a desired shape by selectively removing with a laser abrasion process; (2) a π bond structure in the main chain of a constituting material, wherein the main chain contains an interatomic bond having bond energy smaller than photon energy of laser used for the laser abrasion process.
摘要翻译： 1.一种光学部件，其特征在于，包括基板和层叠有透明聚合物涂膜的光学部件，所述聚合物涂膜包括：（1）通过激光磨蚀工艺选择性去除而形成为所需形状的加工表面; （2）构成材料的主链中的π键结构，其中所述主链含有键合能小于用于激光磨蚀工艺的激光的光子能量的原子间键。
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