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公开(公告)号：US07993833B2
公开(公告)日：2011-08-09
申请号：US11899017
申请日：2007-08-31
申请人： Ann Begovich , Ellen Beasley , Michele Cargill , Steven Schrodi
发明人： Ann Begovich , Ellen Beasley , Michele Cargill , Steven Schrodi
CPC分类号： C12Q1/6883 , A61K31/5377 , C07K16/244 , C07K2317/21 , C07K2317/24 , C07K2317/76 , C12Q2600/106 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172 , G01N33/6893 , G01N2500/04 , G01N2800/205
摘要： The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
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72.发明申请公开(公告)号：US20070041958A1
公开(公告)日：2007-02-22
申请号：US11585926
申请日：2006-10-25
CPC分类号： C12Q1/32 , A01K2217/05 , A61K38/00 , C12N9/0008 , C12Y102/05001 , G01N33/573
摘要： The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the enzyme peptides, and methods of identifying modulators of the enzyme peptides.
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73.发明申请公开(公告)号：US20050003434A1
公开(公告)日：2005-01-06
申请号：US10900420
申请日：2004-07-28
CPC分类号： C12N9/1085
摘要： The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the enzyme peptides, and methods of identifying modulators of the enzyme peptides.
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74.发明申请公开(公告)号：US20050158312A1
公开(公告)日：2005-07-21
申请号：US11014035
申请日：2004-12-17
IPC分类号： C07K14/705 , C12N1/21 , C12N15/12 , C12Q1/68 , A61K39/395 , C07H21/04 , C07K16/28
CPC分类号： C07K14/705
摘要： The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the transporter peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the transporter peptides, and methods of identifying modulators of the transporter peptides.
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75.发明申请公开(公告)号：US20050186613A1
公开(公告)日：2005-08-25
申请号：US11084813
申请日：2005-03-21
申请人： Gennady Merkulov , Karl Guegler , Rhonda Brandon , Karen Ketchum , Valentina Francesco , Ellen Beasley
发明人： Gennady Merkulov , Karl Guegler , Rhonda Brandon , Karen Ketchum , Valentina Francesco , Ellen Beasley
IPC分类号： C07K14/47 , C12Q1/68 , C07H21/04 , C07K14/705 , C07K16/28
CPC分类号： C07K14/47 , A01K2217/05
摘要： The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the transporter peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the transporter peptides, and methods of identifying modulators of the transporter peptides.
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