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公开(公告)号：US20220153952A1
公开(公告)日：2022-05-19
申请号：US17532889
申请日：2021-11-22
发明人： Andrew J. Hess , Qingkun Liu , Ivan I. Smalyukh
摘要： Disclosed are cellulose-based flexible gels containing cellulose nanorods, ribbons, fibers, and the like, and cellulose-enabled inorganic or polymeric composites, wherein the gels have tunable optical, heat transfer, and stiffness properties. The disclosed gels are in the form of hydrogels, organogels, liquid-crystal (LC) gels, and aerogels, depending on the solvents in the gels.
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82.发明授权公开(公告)号：US11298441B2
公开(公告)日：2022-04-12
申请号：US16762835
申请日：2018-11-06
摘要： The present invention relates to the unexpected discovery of 3D printed biomimetics of growth plate cartilage and methods using the same for the treatment of growth plate defects. In certain embodiments, the methods prevent the growth of bony bars at the site of growth plate injury, thereby preventing growth arrest and/or deformity.
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公开(公告)号：US20220057046A1
公开(公告)日：2022-02-24
申请号：US17274881
申请日：2019-09-12
发明人： Daniel Dessau , Justin Griffith
摘要： Methods, systems, and devices for ultra or extreme-high vacuum are described. Such systems may comprise a vacuum chamber, a target within the vacuum chamber, two or more overlapping radiation shields arranged within an inner vacuum space of a vacuum chamber, and surrounding at least a portion of the target, a first and a second cooling element unit thermally coupled to a first and second radiation shield of the two or more overlapping radiation shields, wherein the first unit is configured to reduce the first radiation shield's temperature to at least
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公开(公告)号：US11253210B2
公开(公告)日：2022-02-22
申请号：US15662925
申请日：2017-07-28
发明人： Bernard Jones , Warren Campbell , Moyed Mitten
IPC分类号： A61B5/05 , A61B6/00 , G06T7/00 , A61N5/10 , G06T7/33 , G06T5/50 , G06T5/00 , G06T5/20 , G06T11/00
摘要： Various embodiments of the present technology generally relate to identification of tumor location. More specifically, some embodiments of the present technology relate automated tracking of fiducial marker clusters in x-ray images for the real-time identification of tumor location and guidance of radiation therapy beams. Some embodiments use processed CBCT projection images, an automated routine of reconstruction, forward-projection, tracking, and stabilization generated static templates of the marker cluster at arbitrary viewing angles. Breathing data can be incorporated into some embodiments, resulting in dynamic templates dependent on both viewing angle and breathing motion. In some embodiments, marker clusters can be tracked using normalized cross correlations between templates (either static or dynamic) and CBCT projection images.
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公开(公告)号：US20220013902A1
公开(公告)日：2022-01-13
申请号：US17371682
申请日：2021-07-09
摘要： This disclosure describes systems, methods, and apparatus for beam steering of a circuit-board based phase array of antennas. An RF signal can be distributed via coplanar waveguide conductors to a plurality of microstrip line conductors arranged in a dual-frequency liquid crystal medium. A low frequency control signal can be injected into each of the microstrip line conductors, preferably while each line is still in a coplanar waveguide form. This low frequency control signal modified a local permittivity of the dual-frequency liquid crystal in the vicinity of a corresponding one of the microstrip lines, thereby imparting a controlled phase delay to the RF signal on each microstrip line. This in turn allows a phase-controlled RF signal to be received at each antenna in the array.
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86.发明申请公开(公告)号：US20220003750A1
公开(公告)日：2022-01-06
申请号：US17298646
申请日：2019-12-02
摘要： An ex vivo method of determining sensitivity of multiple myeloma cells obtained from a multiple myeloma patient to chemotherapeutic agents, and methods of specifically treating the patient with chemotherapeutic agents to which the multiple myeloma cells are sensitive.
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公开(公告)号：US11207211B2
公开(公告)日：2021-12-28
申请号：US16302514
申请日：2017-05-18
发明人： Andy Schieber , Linda Thai , Malik Kahook
摘要： A lacrimal drug delivery device includes a reservoir configured to hold a drug. The reservoir is moveable between a relaxed state and an expanded state. A connector is fluidly coupled to the reservoir and a lumen is formed in the connector wherein the drug is configured to flow from the reservoir to an delivery site through the lumen. A hydrogel is within the lumen and configured to absorb the drug from the reservoir and deliver the drug from the lumen at the delivery site. The hydrogel includes a first section which absorbs the drug at a first rate of absorption. A delivery guide is detachably coupled to the reservoir to deliver the reservoir into a lacrimal sac of a patient.
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88.发明申请公开(公告)号：US20210399310A1
公开(公告)日：2021-12-23
申请号：US17288557
申请日：2019-10-25
发明人： Alan W. Weimer , William McNeary
摘要： A method for forming an oxygen reduction reaction (ORR) catalyst (200, 900) may include providing a carbon (210, 910) supported platinum nanoparticle (220, 920) substrate (Pt/C) (110) and applying a tungsten nitride (WN) film (940) onto the surface of the Pt/C substrate (210, 220, 910, 920) using atomic layer deposition (ALD) (120). The Pt/C substrate (210, 220, 910, 920) with the WN film (940) may then be oxidized at a low temperature (130) and annealed at a high temperature in order to reduce WN to metallic tungsten (W) (140). The metallic W forms a blocking layer (230, 930) over coarse Pt nanoparticles (220, 920) and improves the activity and the durability of the Pt/C catalyst (900, 200) when used in fuel cells or related applications.
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公开(公告)号：US20210376555A1
公开(公告)日：2021-12-02
申请号：US17331424
申请日：2021-05-26
申请人： THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE , Government of the United States of America as represented by the Secretary of Commerce
发明人： WEI ZHANG , LIRON STERN , SCOTT B. PAPP
摘要： A monolithic photonic resonator includes a bulk optic with first and second superpolished facets, and a high-reflectivity coating applied to each of the first and second superpolished facets. The superpolished facets form an optical resonator. The bulk optic is a single piece of an optical material that is solid, i.e., has no internal holes, gaps, or pockets. The bulk optic therefore serves as an intraresonator optical medium while still supporting a finesse of 10,000 or more. The superpolished facets may be counterfacing to form a Fabry-Perot cavity. Alternatively, the bulk optic may include forms one or more additional facets off of which light inside the bulk optic undergoes total internal reflection. The monolithic photonic resonator may be mounted in a support structure that minimizes the overall vibration sensitivity of the resonator's resonance frequency.
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公开(公告)号：US20210361579A1
公开(公告)日：2021-11-25
申请号：US17316585
申请日：2021-05-10
摘要： Compositions relating to thermostable vaccines and methods of preparing the same. Specifically, methods of preparing thermostable vaccines based on a recombinant ricin neurotoxin protein and uses of co-adjuvants to develop a composition capable of eliciting an immune response in a subject.
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