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公开(公告)号:USD863060S1
公开(公告)日:2019-10-15
申请号:US29596298
申请日:2017-03-07
Applicant: KOWA COMPANY, LTD.
Designer: Haruyasu Abe , Masato Seki
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82.
公开(公告)号:US20190282139A1
公开(公告)日:2019-09-19
申请号:US16345107
申请日:2017-11-02
Applicant: Kowa Company, Ltd.
Inventor: Takaharu ASANO , Katsumi YABUSAKI
IPC: A61B5/145 , A61B5/1455
Abstract: Provided are an in-blood component measurement method, an in-blood component measurement device, and an in-blood component measurement program, enabling more accurate measurement of a proportion of glycohemoglobin in the total hemoglobin concentration in blood. The in-blood component measurement method is designed to have a constitution including the steps of irradiating, with near-infrared light, blood that is a target to be measured for a proportion of glycohemoglobin in the total hemoglobin concentration in blood, receiving transmitted light of the near-infrared light passing through the blood, measuring an absorption spectrum of the blood on the basis of the transmitted light received, and calculating the proportion for the blood that is the target of measurement by comparing absorbance at a first wavelength range including 1450 nm in the measured absorption spectrum to absorbance at the first wavelength range in the absorption spectrum of blood in which the proportion is already known.
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公开(公告)号:US20190167645A1
公开(公告)日:2019-06-06
申请号:US16272050
申请日:2019-02-11
Applicant: KOWA COMPANY, LTD.
Inventor: Toshiaki Takizawa , Yasunobu Yoshinaka
IPC: A61K31/423 , A61K45/06 , A61K31/397
Abstract: The present invention addresses the problem of providing a pharmaceutical combination composition and drug combinations for the prevention and/or treatment of dyslipidemic conditions such as atherosclerosis, hypercholesterolemia, low HDL blood disease in mammals including humans. A pharmaceutical composition for the prevention and/or treatment of dyslipidemia, etc. which comprises (a) a compound represented by the general formula (1) (in the formula, each symbol is the same as defined in the specification) or a salt thereof or a solvate thereof and (b) a cholesterol absorption inhibitor.
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84.
公开(公告)号:US20190167416A1
公开(公告)日:2019-06-06
申请号:US16309903
申请日:2017-06-14
Applicant: Kowa Company, Ltd.
Inventor: Haruo ISHIKAWA , Akemi TANIGUCHI , Norio SHIMIZU
IPC: A61F2/16
Abstract: There is provided a toric intraocular lens which improves the visibility of a toric axis. The toric intraocular lens is a toric intraocular lens including a lens body provided with an astigmatic axis. A mark indicating the astigmatic axis is formed at an optical surface of an outer rim portion of the lens body, and a length in a radial direction of the lens body and a length in a circumferential direction of the lens body of external dimensions of the mark are different from each other in top view of the optical surface.
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公开(公告)号:US20190117059A1
公开(公告)日:2019-04-25
申请号:US16210038
申请日:2018-12-05
Applicant: KOWA COMPANY, LTD.
Inventor: Satoshi SHIMADA , Takuya HARA
Abstract: In a perimetry to be conducted, designating an inspection region through a region designator, a perimeter is configured to set a required time of the perimetry (upper limit time) through an upper limit condition setter and to determine total number or positions of stimulus presentation spots based upon the upper limit time. In such a configuration, an examinee knows the time to finish the inspection, and is able to highly keep his (her) concentration in comparison with a case where the required time is not known, thereby improving precision of the inspection.
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公开(公告)号:US20180289719A1
公开(公告)日:2018-10-11
申请号:US16005136
申请日:2018-06-11
Applicant: KOWA COMPANY, LTD.
Inventor: Isamu SAWAI
IPC: A61K31/551 , A61K9/08 , A61K31/5575 , A61P27/06 , C08L23/12 , A61K45/06 , A61K47/14 , A61K9/00 , A61K31/18 , A61K31/502
Abstract: A technique is provided for reducing the discoloration of an aqueous composition containing a halogenated isoquinoline derivative during high-temperature preservation. An aqueous composition comprising a compound represented by Formula (1): wherein X represents a halogen atom, or a salt thereof, or a solvate of the compound or the salt thereof, and a prostaglandin.
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公开(公告)号:US09968592B2
公开(公告)日:2018-05-15
申请号:US15513277
申请日:2015-09-28
Applicant: KOWA COMPANY, LTD.
Inventor: Yuta Inokuchi , Haruki Shibata , Toshiaki Takizawa
IPC: A61K31/423 , A61K31/4152 , A61K45/06 , A61K45/00
CPC classification number: A61K31/423 , A61K31/4152 , A61K31/421 , A61K31/505 , A61K45/00 , A61K45/06 , A61K2300/00
Abstract: This invention provides a combination-drug composition and a combination use of pharmaceuticals for preventing and/or treating dyslipidemic conditions such as hyper-LDL cholesterolemia in mammals, including humans.This invention pertains to a drug composition for preventing and/or treating dyslipidemia and the like, the drug composition including the following: (R)-2-[3-[[N-(benzoxazol-2-yl)-N-3-(4-methoxyphenoxy)propyl]aminomethyl]phenoxy] butyric acid, a salt thereof, or a solvate of either; and (S)-trans-{4-[({2-[({1-[3,5-bis(trifluoromethyl)phenyl]ethyl}{5-[2-(methyl sulfonyl)ethoxy]pyrimidin-2-yl}amino)methyl]-4-(trifluoromethyl)phenyl}(ethyl)amino)methyl]cyclohexyl} acetic acid, a salt thereof, or a solvate of either.
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88.
公开(公告)号:US20180028505A1
公开(公告)日:2018-02-01
申请号:US15663784
申请日:2017-07-30
Applicant: Kowa Company, Ltd.
Inventor: Ryu Oshima , Gary Gordon
IPC: A61K31/423 , A61K31/505 , A61K9/00 , A61K31/47 , A61K45/06 , A61K31/40 , A61K31/366
CPC classification number: A61K31/423 , A61K9/0053 , A61K31/366 , A61K31/40 , A61K31/41 , A61K31/47 , A61K31/505 , A61K45/06
Abstract: The present invention provides pharmacological interventions for the treatment of dyslipidemia, and to the reduction of residual risk of cardiovascular disease and adverse cardiovascular events in patients on intense statin use or with well-controlled LDL-C concentrations. In particular, the invention relates to the use of pemafibrate to prevent cardiovascular events in populations at-risk due to risk factors such as type 2 diabetes mellitus with dyslipidemia in spite of intense statin use or well-controlled LDL-C.
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公开(公告)号:US20180014927A1
公开(公告)日:2018-01-18
申请号:US15718675
申请日:2017-09-28
Applicant: KOWA COMPANY, LTD.
Inventor: Asaki SUZAKI
CPC classification number: A61F2/1637 , A61F2/1613 , A61F2240/001 , G02C7/027
Abstract: Provided is an intraocular lens having a novel structure with high utility which is easy to adapt to patients, and can improve quality of vision (QOV). In an intraocular lens, an optical characteristic is set rotationally symmetric around an optical axis, and a spherical aberration of a size corresponding to a coma aberration remaining in a patient's eye after extraction of a human lens of the eye is set.
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公开(公告)号:US20180008144A1
公开(公告)日:2018-01-11
申请号:US15553681
申请日:2016-02-26
Applicant: KOWA COMPANY, LTD.
Inventor: Naoki KOBAYASHI , Masaharu MIZUOCHI , Toshiaki NAKAGAWA
CPC classification number: A61B3/102 , A61B3/0025 , A61B3/0041 , A61B3/10 , A61B3/1025 , A61B3/14 , G01B9/02091 , G06T9/00 , H04N19/00
Abstract: The tomographic image capturing device of the present invention includes a tomographic image capturing means that scans measurement light on a subject's eye fundus (E) to capture tomographic images of the subject's eye fundus and an image processing means that compresses a picture of the captured tomographic images in a scan direction to generate a new tomographic picture. The tomographic image capturing means performs scan at a second scan pitch (PL) narrower than a first scan pitch (PH) to capture the tomographic images of the subject's eye fundus. The image processing means compresses the picture (B11) of the tomographic images captured at the second scan pitch (PL) in the scan direction to generate the new tomographic picture (B12). The measurement width in the scan direction of the new tomographic picture (B12) is a width of a picture corresponding to a measurement width in the scan direction of a tomographic picture (Bn (n=1 to 10)) obtained by scan at the first scan pitch (PH).
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