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公开(公告)号：US20080236596A1
公开(公告)日：2008-10-02
申请号：US11695309
申请日：2007-04-02
CPC分类号： A61B5/02233 , A61B2562/247
摘要： A cuff shield for a pressure cuff comprises a liquid impervious layer and an absorbent layer. The liquid impervious layer includes an outer surface and an inner surface. The outer surface of the liquid impervious layer has an adhesive portion for removably securing the cuff shield to the pressure cuff. The absorbent layer is secured to the liquid impervious layer and includes an outer surface, an inner surface, and a release strip on the outer surface of the absorbent layer. The release strip on the absorbent layer is configured to serve as a protective cover for an adhesive portion on a second cuff shield. This design of the release strip enables delivering the cuff shields on a roll
摘要翻译： 用于压力袖带的袖口罩包括不透液层和吸收层。 液体不可渗透层包括外表面和内表面。 液体不可渗透层的外表面具有粘合部分，用于将袖带防护罩可拆卸地固定到压力袖带上。 吸收层被固定到不透液层，并且在吸收层的外表面上包括外表面，内表面和释放条。 吸收层上的释放带构造成用作第二袖带罩上的粘合剂部分的保护罩。 释放条的这种设计使得能够将卷边罩传送到卷筒上
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公开(公告)号：US20060287603A1
公开(公告)日：2006-12-21
申请号：US11468203
申请日：2006-08-29
IPC分类号： A61B5/02
CPC分类号： A61B5/0261 , A61B5/0053 , A61B5/7207
摘要： An automatic skin perfusion measuring system including instrumentation that automatically analyzes perfusion measurements to identify motion artifact and SPP values and a sensor placement device is provided. The instrumentation is configured to ignore motion artifact. Perfusion measurements are designated as SPP values if various criteria are met. SPP value criteria pertain to factors including cuff pressure, perfusion, perfusion change percentages relative to previous and subsequent perfusion measurements, and whether perfusion measurements are increasing or decreasing relative to previous and subsequent perfusion measurements. The sensor placement device assures reliable data is produced when multiple measurements are desired.
摘要翻译： 一种自动皮肤灌注测量系统，包括自动分析灌注测量以识别运动伪影和SPP值的仪器以及传感器放置装置。 仪器被配置为忽略运动伪影。 如果满足各种标准，灌注测量被指定为SPP值。 SPP值标准涉及包括袖带压力，灌注，相对于先前和随后灌注测量的灌注变化百分比以及灌注测量是否相对于先前和之后的灌注测量值增加或减少的因素。 传感器放置装置确保在需要多次测量时产生可靠数据。
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公开(公告)号：US5976085A
公开(公告)日：1999-11-02
申请号：US946597
申请日：1997-10-07
IPC分类号： G01N1/00 , A61B5/00 , A61B5/145 , A61B5/1459 , A61B5/1473 , A61B5/1495 , A61B5/155 , G01N27/26 , G01N27/416 , G01N33/487
CPC分类号： A61B5/157 , A61B5/14557 , A61B5/1495 , A61B5/15003 , A61B5/150992 , A61B5/155
摘要： A method is provided for calibrating sensors used to analyze characteristics of physiologic fluids such as blood. The method involves the use of a sensor assembly having an analyte-responsive sensor in communication with a passageway which is in divertable fluid communication with a physiologic line and a conduit by which a reference sample may be introduced into the passageway. The method involves exposing the sensor to the reference sample, thereby producing a sensor response. The method also allows performing quality control on the sensors. Also provided is an apparatus with which the claimed method may be practiced.
摘要翻译： 提供了一种用于校准用于分析生理液体如血液的特征的传感器的方法。 该方法包括使用具有分析物响应传感器的传感器组件，该传感器组件与通道相连通，所述通道可与生理线路和可以将参考样品引入通道的导管间流通。 该方法包括将传感器暴露于参考样品，从而产生传感器响应。 该方法还允许对传感器执行质量控制。 还提供了可以实施所要求保护的方法的装置。
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公开(公告)号：US5900215A
公开(公告)日：1999-05-04
申请号：US855939
申请日：1997-05-14
CPC分类号： G01N21/7703 , G01N2021/772 , G01N2021/7759 , G01N2021/7786
摘要： A method is provided for manufacturing a fiber optic sensor for detecting or measuring a parameter of interest in a sample fluid, including pH, concentration of dissolved gases such as O.sub.2 or CO.sub.2, and the like. The sensing chemistry is affixed to the distal end of an elongated optical fiber by way of an adhesive layer typically comprised of an acrylic adhesive composition. Novel optical sensors, fabricated using the aforementioned method, are provided as well.
摘要翻译： 提供了一种用于制造用于检测或测量样品流体中感兴趣的参数的光纤传感器的方法，包括pH，溶解气体如O 2或CO 2的浓度等。 感测化学品通过通常由丙烯酸粘合剂组合物组成的粘合剂层固定在细长光纤的远端。 还提供了使用上述方法制造的新型光学传感器。
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公开(公告)号：US5728422A
公开(公告)日：1998-03-17
申请号：US449846
申请日：1995-05-24
申请人： James Kane , Roy Martin , Anne Perkovich
发明人： James Kane , Roy Martin , Anne Perkovich
CPC分类号： G01N21/643 , G01N21/7703 , G01N2021/6484 , G01N2021/772 , G01N2021/7786 , Y10T436/207497 , Y10T436/209163
摘要： A ratiometric optical sensors method of making is provided to measure dissolved oxygen in a fluid sample. The sensor is formulated so as to contain an oxygen permeable membrane of a cured perfluorinated urethane polymer and, incorporated therein, an oxygen-sensitive indicator component and a reference dye component. The emission spectrum from the indicator component is calibrated by comparison with that of the reference dye, which is substantially less sensitive to oxygen-quenching and which has a photodecomposition rate similar to the indicator component. Methods for making and using the membrane and sensor are provided as well.
摘要翻译： 提供比例式光学传感器制造方法来测量流体样品中的溶解氧。 该传感器被配制成包含固化的全氟化氨基甲酸酯聚合物的透氧膜，并且其中并入有氧敏指示剂组分和参考染料组分。 通过与参考染料的比较来校准来自指示剂组分的发射光谱，其对氧气淬灭基本上较不敏感，并且具有与指示剂组分相似的光分解速率。 还提供了制造和使用膜和传感器的方法。
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公开(公告)号：US5697366A
公开(公告)日：1997-12-16
申请号：US379332
申请日：1995-01-27
IPC分类号： G01N1/00 , A61B5/00 , A61B5/145 , A61B5/1459 , A61B5/1473 , A61B5/1495 , A61B5/155 , G01N27/26 , G01N27/416 , G01N33/487
CPC分类号： A61B5/157 , A61B5/14557 , A61B5/1495 , A61B5/15003 , A61B5/150992 , A61B5/155
摘要： A method is provided for calibrating sensors used to analyze characteristics of physiologic fluids such as blood. The method involves the use of a sensor assembly having an analyte-responsive sensor in communication with a passageway which is in divertable fluid communication with a physiologic line and a conduit by which a reference sample may be introduced into the passageway. The method involves exposing the sensor to the reference sample, thereby producing a sensor response. The method also allows performing quality control on the sensors. Also provided is an apparatus with which the claimed method may be practiced.
摘要翻译： 提供了一种用于校准用于分析生理液体如血液的特征的传感器的方法。 该方法包括使用具有分析物响应传感器的传感器组件，该传感器组件与通道相连通，所述通道可与生理线路和可以将参考样品引入通道的导管间流通。 该方法包括将传感器暴露于参考样品，从而产生传感器响应。 该方法还允许对传感器执行质量控制。 还提供了可以实施所要求保护的方法的装置。
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公开(公告)号：US5681532A
公开(公告)日：1997-10-28
申请号：US449267
申请日：1995-05-24
申请人： James Kane , Roy Martin , Anne Marie Schilling
发明人： James Kane , Roy Martin , Anne Marie Schilling
CPC分类号： G01N21/643 , G01N21/7703 , G01N2021/6484 , G01N2021/772 , G01N2021/7786 , Y10T436/207497 , Y10T436/209163
摘要： A ratiometric method for using optical sensors is provided to measure dissolved oxygen in a fluid sample. The sensor is formulated so as to contain an oxygen permeable membrane of a cured perfluorinated urethane polymer and, incorporated therein, an oxygen-sensitive indicator component and a reference dye component. The emission spectrum from the indicator component is calibrated by comparison with that of the reference dye, which is substantially less sensitive to oxygen-quenching and which has a photodecomposition rate similar to the indicator component. Methods for making and using the membrane and sensor are provided as well.
摘要翻译： 提供了使用光学传感器的比例计方法来测量流体样品中的溶解氧。 该传感器被配制成包含固化的全氟化氨基甲酸酯聚合物的透氧膜，并且其中并入有氧敏指示剂组分和参考染料组分。 通过与参考染料的比较来校准来自指示剂组分的发射光谱，其对氧气淬灭基本上较不敏感，并且具有与指示剂组分相似的光分解速率。 还提供了制造和使用膜和传感器的方法。
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8.发明授权Simultaneous dual excitation/single emission fluorescent sensing method for PH and pCO.sub.2 失效用于PH和pCO2的同时双激发/单发荧光检测方法
公开(公告)号：US5672515A
公开(公告)日：1997-09-30
申请号：US526950
申请日：1995-09-12
申请人： Steven C. Furlong
发明人： Steven C. Furlong
CPC分类号： G01N21/643 , G01N21/7703 , G01N33/84 , G01N2021/6484 , G01N2021/772 , G01N2021/7759 , G01N2021/7786 , G01N2201/062 , Y10T436/204998
摘要： A simultaneous dual excitation/single emission ratiometric method using fiber optic sensors is provided for detecting or measuring a parameter of interest in a sample, including pH, concentration of gases such as CO.sub.2, and the like. The method involves simultaneously providing modulated optical light corresponding to first and second regions of an indicator species' absorption or excitation spectrum, detecting modulated emission signals from the indicator species, demodulating the emission signals, calculating the apparent quantity of analyte present in the sample from the indicator emission signals and correcting the apparent quantity of analyte present for variations resulting from external factors, by determining the ratio of the demodulated indicator emission signals. An apparatus is provided for performing the method as well.
摘要翻译： 提供了使用光纤传感器的同时双激发/单发射比例法，用于检测或测量样品中感兴趣的参数，包括pH，诸如CO 2等气体的浓度。 该方法包括同时提供对应于指示物种吸收或激发光谱的第一和第二区域的调制光学光，检测来自指示物质的调制的发射信号，解调发射信号，计算从样品中存在的分析物的表观量 指示符发射信号，并且通过确定解调的指示符发射信号的比率来校正存在的用于由外部因素引起的变化的分析物的表观量。 提供了一种用于执行该方法的装置。
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公开(公告)号：US5536783A
公开(公告)日：1996-07-16
申请号：US453633
申请日：1995-05-30
申请人： Alan Olstein , William Fowler , Jo Pritchard
发明人： Alan Olstein , William Fowler , Jo Pritchard
IPC分类号： G01N21/80 , C08F290/00 , C08F290/06 , C08L75/14 , G01N21/64 , G01N21/77 , C08F8/30 , C08L75/00
CPC分类号： G01N21/7703 , G01N21/6428 , G01N33/84 , G01N2021/6434 , G01N2021/772 , G01N2021/773 , G01N2021/7786 , G01N21/80
摘要： An optical sensor is provided for measuring the pH of a fluid sample. The sensor is formulated using a fluorescent polymer composition comprising a copolymer of a water-dispersable, polyether-containing urethane olefin precursor and a fluorescent monomer species, wherein the ratio of precursor and fluorescent monomer species is such that a predetermined apparent pKa is provided. The sensor is prepared by coating the distal end of an optical waveguide with the fluorescent polymer composition, and curing the copolymer contained in the composition, e.g., by exposure to radiation of a suitable wavelength.
摘要翻译： 提供了用于测量流体样品的pH的光学传感器。 使用包含可水分散性聚醚的聚氨酯烯烃前体和荧光单体种类的共聚物的荧光聚合物组合物来配制传感器，其中前体和荧光单体种类的比例使得提供预定的表观pKa。 通过用荧光聚合物组合物涂覆光波导的远端并且例如通过暴露于合适波长的辐射来固化包含在组合物中的共聚物来制备传感器。
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公开(公告)号：US5714121A
公开(公告)日：1998-02-03
申请号：US535878
申请日：1995-09-28
IPC分类号： G01N21/78 , A61B5/145 , A61B5/1455 , A61B5/1495 , G01N21/64 , G01N21/77 , G01N21/80 , G01N31/22 , G01N33/00
CPC分类号： G01N21/643 , G01N21/7703 , G01N31/223 , G01N33/004 , G01N2021/6432 , G01N2021/7786 , G01N21/783 , G01N21/80
摘要： A method is provided for manufacturing a fiber optic sensor for detecting or measuring the concentration of carbon dioxide in a sample fluid. The method involves incorporation of a fluorescent indicator composition in a silicone capsule slidably arranged over the tip of a fiber optic, sealed with a suitable adhesive. To amplify the detectable signal obtained, the capsule is preferably fabricated so as to contain reflective particles, and tapers to a narrow tip. Novel optical sensors, manufactured using the aforementioned method, are provided as well.
摘要翻译： 提供了一种用于制造用于检测或测量样品流体中二氧化碳浓度的光纤传感器的方法。 该方法包括将荧光指示剂组合物结合到可滑动地布置在光纤的尖端上的硅胶囊中，并用合适的粘合剂密封。 为了扩增所获得的可检测信号，胶囊优选地被制造成包含反射颗粒，并且变细到尖端。 也提供使用上述方法制造的新型光学传感器。
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