公开(公告)号：US20180368950A1

公开(公告)日：2018-12-27

申请号：US16062695

申请日：2016-12-11

申请人： HAGAY JACOBSEN ,  AARON HOFFMAN

发明人： HAGAY JACOBSEN ,  AARON HOFFMAN

IPC分类号： A61C8/00

摘要： A pluggable implant is disclosed that is comprising an implant body extending between a distal end and an apical end, and comprising a cavity extending from the distal end towards the apical end, the cavity capable of accommodating a plug insertable from the distal end towards the apical end, such that when the plug is fully inserted and located in its apically-most position, the plug seals the cavity. Moreover, there is a method for plugging a hollow implant is disclosed, the implant comprising an implant body extending between a distal end and an apical end, and comprising a cavity extending from the distal end towards the apical end; wherein a plug is removably inserted into the implant through the cavity from the distal end towards the apical end such that when the plug is in fully inserted position and located in its apically-most position, the plug seals the cavity.

公开(公告)号：US20100152525A1

公开(公告)日：2010-06-17

申请号：US12656959

申请日：2010-02-22

申请人： Gabi Weizman ,  Aaron Hoffman

发明人： Gabi Weizman ,  Aaron Hoffman

IPC分类号： A61M1/10

CPC分类号： A61M1/1037 ,  A61M1/1008 ,  A61M1/106 ,  A61M1/1062 ,  A61M1/1067 ,  A61M1/1086 ,  A61M1/12 ,  A61M1/122 ,  A61M1/127 ,  A61M2205/32

摘要： A peri-arterial blood flow booster apparatus for improving blood pressure and flow, to be implanted around a blood vessel of a patient. The booster comprises a pressure applying device (56) comprising at least one balloon (44), placed alongside a portion of the blood vessel and a restrainer (54) for restraining the balloon and providing counter-forces. It further comprises a control console (60) comprising: an inflating unit (66) for rapidly inflating and deflating the balloon, the inflating unit connected to the balloon; sensing means (68) for sensing electrocardiograph signals of the patient; a control unit (72) for controlling the operation of the inflating unit correlating to the electrocardiograph signals detected by the sensing means. When the balloon is inflated the restrainer forces it to compress the portion of the blood vessel preventing backflow and exerting forces on the blood vessel forcing blood within the portion of the blood vessel to flow antegradely.

摘要翻译： 一种用于改善血液和流动的周围动脉血流增压装置，其被植入患者的血管周围。 增压器包括压力施加装置（56），该压力施加装置（56）包括至少一个放置在血管的一部分上的球囊（44）和用于限制球囊并提供反作用力的限制器（54）。 其还包括控制台（60），包括：充气单元（66），其用于使气囊快速充气和放气，所述充气单元连接到气囊; 感测装置（68），用于感测患者的心电图信号; 用于控制与由感测装置检测到的心电图仪信号相关的充气单元的操作的控制单元（72）。 当气球膨胀时，限制器迫使其压缩血管部分以防止回流并且在血管上施加力，迫使血管部分内的血液顺畅地流动。

公开(公告)号：US20070260323A1

公开(公告)日：2007-11-08

申请号：US11611021

申请日：2006-12-14

申请人： Brian Earl ,  Abraham Habegger ,  Aaron Hoffman ,  Kim Bertin ,  Lawrence Dorr ,  Robert Booth ,  Aaron Rosenberg ,  Sergio Romagnoli

发明人： Brian Earl ,  Abraham Habegger ,  Aaron Hoffman ,  Kim Bertin ,  Lawrence Dorr ,  Robert Booth ,  Aaron Rosenberg ,  Sergio Romagnoli

IPC分类号： A61F2/38

CPC分类号： A61F2/3859 ,  A61F2002/30324 ,  A61F2002/30616 ,  A61F2002/30667

摘要： A set of distal femoral knee prostheses which are designed to be more narrow in medial/lateral dimensions with increasing anterior/posterior size than existing prostheses to more closely correspond to the physical anatomy of female patients. The prostheses are designed to have a substantially trapezoidal shape or profile when viewed distally which features a more pronounced narrowing of the medial/lateral dimensions beginning at the posterior end of the prostheses and progressing anteriorly to the anterior end of the prostheses. Additionally, the prostheses each include a reduced profile patellar sulcus and reduced profile anterior condyles to more closely conform to the anatomy of a resected femur, and also include sulcus tracking optimized to conform to female anatomy.

摘要翻译： 一组远端股骨膝关节假体被设计为内侧/外侧尺寸更窄，前后尺寸比现有假体增加，以更接近于女性患者的身体解剖结构。 假肢被设计成当远端观察时具有基本上梯形的形状或轮廓，其特征在于在假体的后端开始并在假体的前端前进的内侧/外侧尺寸更明显变窄。 此外，假体各自包括减小的轮廓髌骨沟和减小的轮廓前髁，以更紧密地与切除的股骨的解剖结构一致，并且还包括优化以符合女性解剖结构的沟槽跟踪。

公开(公告)号：US20070015174A1

公开(公告)日：2007-01-18

申请号：US11339294

申请日：2006-01-25

申请人： Matthew Duan ,  Charles McDermott ,  Aaron Hoffman ,  Lansing Stewart ,  Thorsteinn Thorsteinsson ,  Robert O'Fee ,  David Zembower

发明人： Matthew Duan ,  Charles McDermott ,  Aaron Hoffman ,  Lansing Stewart ,  Thorsteinn Thorsteinsson ,  Robert O'Fee ,  David Zembower

IPC分类号： C12Q1/68 ,  G01N33/53

CPC分类号： G01N33/15

摘要： Methods for screening compounds for their solubility and their solution stability in a variety of diverse formulations and sets of diverse formulations useful for screening compounds for their solubility and their solution stability.

摘要翻译： 筛选化合物的溶解度及其溶液稳定性的方法可用于各种不同配方和多种制剂的组合，用于筛选化合物的溶解度及其溶液稳定性。

公开(公告)号：US20060027780A1

公开(公告)日：2006-02-09

申请号：US11171640

申请日：2005-06-30

申请人： Michael Feese ,  Aaron Hoffman

发明人： Michael Feese ,  Aaron Hoffman

IPC分类号： A23J7/00

CPC分类号： C30B29/58 ,  C30B7/00

摘要： In one aspect, the present invention provides sets of crystallization solutions that each include one of Crystallization Solution Set 1, Crystallization Solution Set 2, Crystallization Solution Set 3, and Crystallization Solution Set 4. In another aspect, the present invention provides kits that each include at least one crystallization plate and a Crystallization Solution Set of the invention.

摘要翻译： 在一个方面，本发明提供了各自包括结晶溶液组1，结晶溶液组2，结晶溶液组3和结晶溶液组4中的一种的结晶溶液组。另一方面，本发明提供了各自包括 本发明的至少一种结晶板和结晶溶液组。

公开(公告)号：US20060183963A1

公开(公告)日：2006-08-17

申请号：US10560825

申请日：2004-06-16

申请人： Gabi Weizman ,  Aaron Hoffman

发明人： Gabi Weizman ,  Aaron Hoffman

IPC分类号： A61N1/362

CPC分类号： A61M1/1037 ,  A61M1/1008 ,  A61M1/106 ,  A61M1/1062 ,  A61M1/1067 ,  A61M1/1086 ,  A61M1/12 ,  A61M1/122 ,  A61M1/127 ,  A61M2205/32

摘要： A peri-arterial blood flow booster apparatus for improving blood pressure and flow, to be implanted around a blood vessel of a patient. The booster comprises a pressure applying device (56) comprising at least one balloon (44), placed alongside a portion of the blood vessel and a restrainer (54) for restraining the balloon and providing counter-forces. It further comprises a control console (60) comprising: an inflating unit (66) for rapidly inflating and deflating the balloon, the inflating unit connected to the balloon; sensing means (68) for sensing electrocardiograph signals of the patient; a control unit (72) for controlling the operation of the inflating unit correlating to the electrocardiograph signals detected by the sensing means. When the balloon is inflated the restrainer forces it to compress the portion of the blood vessel preventing backflow and exerting forces on the blood vessel forcing blood within the portion of the blood vessel to flow antegradely.

摘要翻译： 一种用于改善血液和流动的周围动脉血流增压装置，其被植入患者的血管周围。 增压器包括压力施加装置（56），该压力施加装置（56）包括至少一个放置在血管的一部分上的球囊（44）和用于限制球囊并提供反作用力的限制器（54）。 其还包括控制台（60），包括：充气单元（66），其用于使气囊快速充气和放气，所述充气单元连接到气囊; 感测装置（68），用于感测患者的心电图信号; 用于控制与由感测装置检测到的心电图仪信号相关的充气单元的操作的控制单元（72）。 当气球膨胀时，限制器迫使其压缩血管部分以防止回流并且在血管上施加力，迫使血管部分内的血液顺畅地流动。

公开(公告)号：US07666131B2

公开(公告)日：2010-02-23

申请号：US10560825

申请日：2004-06-16

申请人： Gabi Weizman ,  Aaron Hoffman

发明人： Gabi Weizman ,  Aaron Hoffman

IPC分类号： A61N1/362

CPC分类号： A61M1/1037 ,  A61M1/1008 ,  A61M1/106 ,  A61M1/1062 ,  A61M1/1067 ,  A61M1/1086 ,  A61M1/12 ,  A61M1/122 ,  A61M1/127 ,  A61M2205/32

摘要： A peri-arterial blood flow booster apparatus for improving blood pressure and flow, to be implanted around a blood vessel of a patient. The booster comprises a pressure applying device (56) comprising at least one balloon (44), placed alongside a portion of the blood vessel and a restrainer (54) for restraining the balloon and providing counter-forces. It further comprises a control console (60) comprising: an inflating unit (66) for rapidly inflating and deflating the balloon, the inflating unit connected to the balloon; sensing means (68) for sensing electrocardiograph signals of the patient; a control unit (72) for controlling the operation of the inflating unit correlating to the electrocardiograph signals detected by the sensing means. When the balloon is inflated the restrainer forces it to compress the portion of the blood vessel preventing backflow and exerting forces on the blood vessel forcing blood within the portion of the blood vessel to flow antegradely.