公开(公告)号：US20050167365A1

公开(公告)日：2005-08-04

申请号：US10523092

申请日：2003-07-29

申请人： Henning Schramm ,  Achim Kienle ,  Malte Kaspereit ,  Andreas Seidel-Morgenstern

发明人： Henning Schramm ,  Achim Kienle ,  Malte Kaspereit ,  Andreas Seidel-Morgenstern

IPC分类号： B01D15/18 ,  B01D15/08

CPC分类号： B01D15/1828 ,  B01D2215/023

摘要： The invention relates to a process for the chromatographic separation of components (19, 20, 25, 26, 28, 29) of a multiple-component fluid mixture (2a) by means of the Simulated Moving Bed process, in which the multiple-component fluid mixture (2a) and at least one solvent (3a) are passed into a plurality of at least one chamber (10a-10c; 11a-11c; 12a-12c; 13a-13c) or chamber sections containing a solid, at a first and second input (9b, 9d; 9f, 9h), and an extract flow (6a), which contains at least one first component (19, 26, 29) separated from the multiple-component fluid mixture (2a), as well as a raffinate flow (7a), which contains at least one second component (20, 25, 28) separated from the multiple-component fluid mixture (2a) are drawn off from the chambers (10a-10c; 11a-11c; 12a-12c; 13a-13c) or chamber sections at a first and second outlet (9a, 9c; 9e, 9g), whereby the chambers (10a-10c; 11a-11c; 12a-12c; 13a-13c) or chamber sections forming a closed circuit (8a, 8b; 18) are connected together in series, whereby the concentration of the input multiple-component fluid mixture (2a) and/or a composition of the solvent (3a) is/are changed within the cycle unit.

摘要翻译： 本发明涉及通过模拟移动床方法对多组分流体混合物（2a）的组分（19,20,25,26,28,29）进行色谱分离的方法， 组分流体混合物（2a）和至少一种溶剂（3a）通入多个至少一个室（10a- -10c; 11a- 11c; 12a-12c; 13a-13c ）或在第一和第二输入（9b，9d; 9f，9h）处含有固体的室部分）和提取物流（6a），其包含至少一个第一组分（19,26,29 ）以及提余液流（7a），其含有与多组分流体混合物（2a）分离的至少一个第二组分（20,25,28），所述第二组分（20,25,28）与多组分流体混合物 ）在第一和第二出口（9a，9b; 9e）处从室（10a-10c; 11a-11c; 12a-12c; 13a-13c）或室部分 ，9g），由此腔室（10a-10c; 11a-11c; 12a-1） 2 c; 13a-13c）或形成闭合回路（8 a，8 b; 18）的腔室部分串联连接在一起，由此输入的多组分流体混合物（2a）和/或 溶剂（3a）在循环单元内变化。

公开(公告)号：US07479228B2

公开(公告)日：2009-01-20

申请号：US10523092

申请日：2003-07-29

申请人： Henning Schramm ,  Achim Kienle ,  Malte Kaspereit ,  Andreas Seidel-Morgenstern

发明人： Henning Schramm ,  Achim Kienle ,  Malte Kaspereit ,  Andreas Seidel-Morgenstern

IPC分类号： B01D15/08

CPC分类号： B01D15/1828 ,  B01D2215/023

摘要： The invention relates to a process for the chromatographic separation of components (19, 20, 25, 26, 28, 29) of a multiple-component fluid mixture (2a) by means of the Simulated Moving Bed process, in which the multiple-component fluid mixture (2a) and at least one solvent (3a) are passed into a plurality of at least one chamber (10a-10c; 11a-11c; 12a-12c; 13a-13c) or chamber sections containing a solid, at a first and second input (9b, 9d; 9f, 9h), and an extract flow (6a), which contains at least one first component (19, 26, 29) separated from the multiple-component fluid mixture (2a), as well as a raffinate flow (7a), which contains at least one second component (20, 25, 28) separated from the multiple-component fluid mixture (2a) are drawn off from the chambers (10a-10c; 11a-11 c; 12a-12c; 13a-13c) or chamber sections at a first and second outlet (9a, 9c; 9e, 9g), whereby the chambers (10a-10c; 11a-11c; 12a-12c; 13a-13c) or chamber sections forming a closed circuit (8a, 8b; 18) are connected together in series, whereby the concentration of the input multiple-component fluid mixture (2a) and/or a composition of the solvent (3a) is/are changed within the cycle unit.

摘要翻译： 本发明涉及通过模拟移动床方法对多组分流体混合物（2a）的组分（19,20,25,26,28,29）进行色谱分离的方法，其中多组分 流体混合物（2a）和至少一种溶剂（3a）在第一种方式被引入多个至少一个室（10a-10c; 11a-11c; 12a-12c; 13a-13c）或包含固体的室部分 和第二输入（9b，9d; 9f，9h）和提取流（6a），其包含与多组分流体混合物（2a）分离的至少一个第一组分（19,26,29），以及 包含与多组分流体混合物（2a）分离的至少一个第二组分（20,25,28）的萃余液流（7a）从室（10a-10c; 11a-11c; 12a- （9a，9c; 9e，9g）的腔室部分，其中腔室（10a-10c; 11a-11c; 12a-12c; 13a-13c）或腔室部分形成 闭路（8a，8b; 18） 串联连接在一起，由此输入的多组分流体混合物（2a）和/或溶剂（3a）的组合物的浓度在循环单元内变化。