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公开(公告)号:US20110070581A1
公开(公告)日:2011-03-24
申请号:US12768573
申请日:2010-04-27
申请人: Amit Gupta , Alan Rosenbach , Aman Russom , Kenneth T. Kotz , Mehmet Toner , Ronald G. Tompkins
发明人: Amit Gupta , Alan Rosenbach , Aman Russom , Kenneth T. Kotz , Mehmet Toner , Ronald G. Tompkins
IPC分类号: C12Q1/68 , C12Q1/04 , C12N5/078 , C12N5/0786
CPC分类号: G01N33/56972
摘要: Leukocytes (e.g., neutrophils, monocytes and/or lymphocytes) can be captured and separated from blood by removing platelets using a spiral channel, followed by capturing individual leukocyte types in a series of cell capture channels having leukocyte binding moieties. Accordingly, various microfluidic-based cell affinity chromatography methods can be used to separate leukocytes from whole blood.
摘要翻译: 通过使用螺旋通道去除血小板,然后在一系列具有白细胞结合部分的细胞捕获通道中捕获单个白细胞类型,可以捕获白细胞(例如嗜中性粒细胞,单核细胞和/或淋巴细胞)并从血液中分离。 因此,可以使用各种基于微流体的细胞亲和层析方法将白细胞与全血分离。