公开(公告)号：US20090248141A1

公开(公告)日：2009-10-01

申请号：US12295594

申请日：2007-03-30

申请人： Robin Shandas ,  Christopher M. Yakacki ,  Kenneth Gall ,  Alex E. Eckstein ,  Michael Lyons ,  Devatha P. Nair

发明人： Robin Shandas ,  Christopher M. Yakacki ,  Kenneth Gall ,  Alex E. Eckstein ,  Michael Lyons ,  Devatha P. Nair

IPC分类号： A61F2/92 ,  A61M29/00 ,  A61M29/04 ,  B29C35/02

CPC分类号： A61B17/12022 ,  A61B17/12099 ,  A61B17/12159 ,  A61B17/12163 ,  A61B17/1219 ,  A61B2017/00526 ,  A61B2017/00867 ,  A61F2/844 ,  A61F2/88 ,  A61F2/91 ,  A61F2/92 ,  A61F2220/0016 ,  A61L31/048 ,  A61L31/14 ,  A61L2400/16 ,  C08L33/04

摘要： Medical devices for in vivo medical applications are disclosed. The medical devices are constructed of shape memory polymer (SMP) materials capable of assuming a memory shape at physiological temperatures. These medical devices may be used in surgical procedures and in both vascular and non-vascular applications. These SMP medical devices have a post-implantation memory shape that is substantially identical to or slightly larger than the insertion site to adapt to vessel growth or size changes. SMP medical devices may be formed as stents or occlusion devices (i.e., plugs) having a number of different structural features. The SMP medical devices may be formed from a first monomer and a second cross-linking monomer, wherein the weight percentages of the first and second monomers are selected by performing an iterative function to reach a predetermined glass transition temperature (Tg) and a predetermined rubbery modulus to optimize post-implantation memory shape properties of the devices.

摘要翻译： 公开了用于体内医疗应用的医疗装置。 医疗器械由能够在生理温度下呈现记忆形状的形状记忆聚合物（SMP）材料构成。 这些医疗装置可用于外科手术和血管和非血管应用。 这些SMP医疗装置具有植入后记忆形状，其基本上与插入位点相同或略大，以适应血管生长或尺寸变化。 SMP医疗装置可以形成为具有多个不同结构特征的支架或闭塞装置（即插头）。 SMP医疗装置可以由第一单体和第二交联单体形成，其中第一和第二单体的重量百分比通过执行迭代函数来选择以达到预定的玻璃化转变温度（Tg）和预定的橡胶状 模数以优化植入后记忆形状特性的器件。