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    Shape Memory Polymer Medical Devices
    1.
    发明申请
    Shape Memory Polymer Medical Devices 审中-公开
    形状记忆聚合物医疗器械

    公开(公告)号：US20090248141A1

    公开(公告)日：2009-10-01

    申请号：US12295594

    申请日：2007-03-30

    申请人： Robin Shandas ,  Christopher M. Yakacki ,  Kenneth Gall ,  Alex E. Eckstein ,  Michael Lyons ,  Devatha P. Nair

    发明人： Robin Shandas ,  Christopher M. Yakacki ,  Kenneth Gall ,  Alex E. Eckstein ,  Michael Lyons ,  Devatha P. Nair

    IPC分类号： A61F2/92 ,  A61M29/00 ,  A61M29/04 ,  B29C35/02

    CPC分类号： A61B17/12022 ,  A61B17/12099 ,  A61B17/12159 ,  A61B17/12163 ,  A61B17/1219 ,  A61B2017/00526 ,  A61B2017/00867 ,  A61F2/844 ,  A61F2/88 ,  A61F2/91 ,  A61F2/92 ,  A61F2220/0016 ,  A61L31/048 ,  A61L31/14 ,  A61L2400/16 ,  C08L33/04

    摘要： Medical devices for in vivo medical applications are disclosed. The medical devices are constructed of shape memory polymer (SMP) materials capable of assuming a memory shape at physiological temperatures. These medical devices may be used in surgical procedures and in both vascular and non-vascular applications. These SMP medical devices have a post-implantation memory shape that is substantially identical to or slightly larger than the insertion site to adapt to vessel growth or size changes. SMP medical devices may be formed as stents or occlusion devices (i.e., plugs) having a number of different structural features. The SMP medical devices may be formed from a first monomer and a second cross-linking monomer, wherein the weight percentages of the first and second monomers are selected by performing an iterative function to reach a predetermined glass transition temperature (Tg) and a predetermined rubbery modulus to optimize post-implantation memory shape properties of the devices.

    摘要翻译： 公开了用于体内医疗应用的医疗装置。 医疗器械由能够在生理温度下呈现记忆形状的形状记忆聚合物（SMP）材料构成。 这些医疗装置可用于外科手术和血管和非血管应用。 这些SMP医疗装置具有植入后记忆形状，其基本上与插入位点相同或略大，以适应血管生长或尺寸变化。 SMP医疗装置可以形成为具有多个不同结构特征的支架或闭塞装置（即插头）。 SMP医疗装置可以由第一单体和第二交联单体形成，其中第一和第二单体的重量百分比通过执行迭代函数来选择以达到预定的玻璃化转变温度（Tg）和预定的橡胶状 模数以优化植入后记忆形状特性的器件。

    Programmable radio frequency waveform generator for a synchrocyclotron
    3.
    发明授权
    Programmable radio frequency waveform generator for a synchrocyclotron 有权

    公开(公告)号：US08952634B2

    公开(公告)日：2015-02-10

    申请号：US12603934

    申请日：2009-10-22

    申请人： Alan Sliski ,  Kenneth Gall

    发明人： Alan Sliski ,  Kenneth Gall

    IPC分类号： H05H15/00 ,  H05H13/02

    CPC分类号： H05H13/02

    摘要： A synchrocyclotron comprises a resonant circuit that includes electrodes having a gap therebetween across the magnetic field. An oscillating voltage input, having a variable amplitude and frequency determined by a programmable digital waveform generator generates an oscillating electric field across the gap. The synchrocyclotron can include a variable capacitor in circuit with the electrodes to vary the resonant frequency. The synchrocyclotron can further include an injection electrode and an extraction electrode having voltages controlled by the programmable digital waveform generator. The synchrocyclotron can further include a beam monitor. The synchrocyclotron can detect resonant conditions in the resonant circuit by measuring the voltage and or current in the resonant circuit, driven by the input voltage, and adjust the capacitance of the variable capacitor or the frequency of the input voltage to maintain the resonant conditions. The programmable waveform generator can adjust at least one of the oscillating voltage input, the voltage on the injection electrode and the voltage on the extraction electrode according to beam intensity and in response to changes in resonant conditions.

    CHARGED PARTICLE RADIATION THERAPY
    4.
    发明申请
    CHARGED PARTICLE RADIATION THERAPY 有权
    充电颗粒辐射治疗

    公开(公告)号：US20120126140A1

    公开(公告)日：2012-05-24

    申请号：US13303110

    申请日：2011-11-22

    申请人： Kenneth Gall ,  Stanley Rosenthal ,  Gordon Row ,  Michael Ahearn

    发明人： Kenneth Gall ,  Stanley Rosenthal ,  Gordon Row ,  Michael Ahearn

    IPC分类号： A61N5/10

    CPC分类号： A61N5/1081 ,  A61N5/10 ,  A61N2005/1087 ,  H05H7/04 ,  H05H13/02 ,  H05H13/04 ,  H05H2007/043

    摘要： A system includes a patient support and an outer gantry on which an accelerator is mounted to enable the accelerator to move through a range of positions around a patient on the patient support. The accelerator is configured to produce a proton or ion beam having an energy level sufficient to reach a target in the patient. An inner gantry includes a robotic arm capable of directing an aperture for directing the proton or ion beam towards the target.

    摘要翻译： 一种系统包括患者支撑件和外部龙门架，在其上安装有加速器，以使加速器能够移动穿过患者支架上的患者周围的位置范围。 加速器被配置为产生具有足以达到患者中的目标的能量水平的质子或离子束。 内部龙门架包括能够引导用于将质子或离子束引向目标的孔的机器人手臂。

    Charged particle radiation therapy
    5.
    发明授权
    Charged particle radiation therapy 有权
    带电粒子放射治疗

    公开(公告)号：US07728311B2

    公开(公告)日：2010-06-01

    申请号：US11601056

    申请日：2006-11-17

    申请人： Kenneth Gall

    发明人： Kenneth Gall

    IPC分类号： H01J37/08 ,  H01F6/00

    CPC分类号： A61N5/1081 ,  A61N5/10 ,  A61N2005/1087 ,  H05H7/04 ,  H05H13/02 ,  H05H13/04 ,  H05H2007/043

    摘要： Among other things, an accelerator is mounted on a gantry to enable the accelerator to move through a range of positions around a patient on a patient support. The accelerator is configured to produce a proton or ion beam having an energy level sufficient to reach any arbitrary target in the patient from positions within the range. The proton or ion beam passes essentially directly from the accelerator to the patient. In some examples, the synchrocyclotron has a superconducting electromagnetic structure that generates a field strength of at least 6 Tesla, produces a beam of particles having an energy level of at least 150 MeV, has a volume no larger than 4.5 cubic meters, and has a weight less than 30 Tons.

    摘要翻译： 除其他之外，加速器安装在台架上以使加速器可以在患者支架上的患者周围移动一定范围的位置。 加速器被配置为产生具有足以从该范围内的位置到达患者任何任意目标的能级的质子或离子束。 质子或离子束基本上直接从加速器传递给患者。 在一些实例中，同步回旋加速器具有产生至少6特斯拉的场强的超导电磁结构，产生具有至少150MeV的能级的粒子束，具有不大于4.5立方米的体积，并具有 重量小于30吨。

    Programmable particle scatterer for radiation therapy beam formation
    6.
    发明申请
    Programmable particle scatterer for radiation therapy beam formation 失效
    用于放射治疗束形成的可编程粒子散射体

    公开(公告)号：US20060017015A1

    公开(公告)日：2006-01-26

    申请号：US10949734

    申请日：2004-09-24

    申请人： Alan Sliski ,  Kenneth Gall

    发明人： Alan Sliski ,  Kenneth Gall

    IPC分类号： A61N5/10

    CPC分类号： A61N5/1077 ,  A61N2005/1087 ,  A61N2005/1095 ,  G21K1/08 ,  G21K5/04 ,  H05H7/00

    摘要： Interposing a programmable path length of one or more materials into a particle beam modulates scattering angle and beam range in a predetermined manner to create a predetermined spread out Bragg peak at a predetermined range. Materials can be “low Z” and “high Z” materials that include fluids. A charged particle beam scatterer/range modulator can comprise a fluid reservoir having opposing walls in a particle beam path and a drive to adjust the distance between the walls of the fluid reservoir under control by a programmable controller. A “high Z” and, independently, a “low Z” reservoir, arranged in series, can be used. When used for radiation treatment, the beam can be monitored by measuring beam intensity, and the programmable controller can adjust the distance between the opposing walls of the “high Z” reservoir and, independently, the distance between the opposing walls of the “low Z” reservoir according to a predetermined relationship to integral beam intensity. Beam scattering and modulation can be done continuously and dynamically during a treatment in order to deposit dose in a target volume in a predetermined three dimensional distribution.

    摘要翻译： 将一个或多个材料的可编程路径长度插入到粒子束中，以预定方式调制散射角和波束范围，以在预定范围产生预定的扩展布拉格峰。 材料可以是包括流体的“低Z”和“高Z”材料。 带电粒子束散射体/范围调制器可以包括在粒子束路径中具有相对壁的流体储存器，以及通过可编程控制器来控制流体储存器的壁之间的距离的驱动器。 可以使用串联布置的“高Z”和独立地“低Z”储存器。 当用于辐射处理时，可以通过测量光束强度来监视光束，并且可编程控制器可以调节“高Z”储存器的相对壁之间的距离，并且独立地调节“低Z”储存器的相对壁之间的距离 “储层按照与整体光束强度的预定关系。 光束散射和调制可以在处理期间连续且动态地进行，以便以预定的三维分布将剂量沉积在目标体积中。

    Sensor with molded sensor diaphragm cover
    7.
    发明申请
    Sensor with molded sensor diaphragm cover 失效

    公开(公告)号：US20050028596A1

    公开(公告)日：2005-02-10

    申请号：US10635277

    申请日：2003-08-06

    申请人： Kenneth Gall

    发明人： Kenneth Gall

    IPC分类号： B60C23/04 ,  G01L7/08 ,  G01L9/00

    CPC分类号： G01L9/0064 ,  B60C23/0408 ,  G01L9/0025

    摘要： A diaphragm cover apparatus and method for a sensor are disclosed. A sensor cover is located proximate to a base. A dimple can be located centrally within the cover, wherein the dimple comprises a component that is separate from the sensor cover and diaphragm. The dimple contacts a sense element of the sensor. Additionally, a foil can be adapted for use in blocking air permeation through the sensor diaphragm, when the sensor experiences pressure. An over mold diaphragm is generally located as part of the sensor cover. The dimple itself comprises a highly polished surface to reduce stress concentrators from contacting the sense element. The dimple can be formed from materials such as stainless steel, ceramic and the like to optimize the performance of the sensor.