公开(公告)号：US10143456B2

公开(公告)日：2018-12-04

申请号：US11245421

申请日：2005-10-07

申请人： Alex Javois

发明人： Alex Javois

IPC分类号： A61B17/00 ,  A61B17/12

摘要： A left atrial appendage occlusion device includes a deformable wire having a proximal portion and a distal portion, wherein the deformable wire is configured to form a first predetermined expanded shape and a second predetermined relaxed shape; a distal anchor that includes a plurality of hooks or barbs extending from a point at an overall distal end of the deformable wire, the distal anchor being configured to attach the device to an interior wall of the left atrial appendage; and a sheet attached to the proximal portion of the deformable wire.

公开(公告)号：US20070083230A1

公开(公告)日：2007-04-12

申请号：US11245421

申请日：2005-10-07

申请人： Alex Javois

发明人： Alex Javois

IPC分类号： A61B17/08

CPC分类号： A61B17/0057 ,  A61B17/12022 ,  A61B17/12122 ,  A61B17/12172 ,  A61B2017/00575 ,  A61B2017/00579 ,  A61B2017/00592 ,  A61B2017/00597 ,  A61B2017/00615 ,  A61B2017/00632 ,  A61B2017/00867

摘要： The present invention provides devices and methods for occluding the left atrial appendage. The device includes an easily deployed wire structure of shape memory material sized to be appropriate for use in a patient. The device may be manufactured in various sizes for use in various patients. The device has a sheet of material attached for eclipsing the opening of the left atrial appendage and means for secured attachment substantially within the left atrial appendage. The method includes deploying the device within the left atrial appendage, securely anchoring the device, and ensuring that a sheet of material eclipses the opening of the left atrial appendage. These features are incorporated into the improved devices and methods in order to more effectively aid in the prevention of clot formation and clot migration into or out of the left atrial appendage to greatly decrease the risk of stroke in patients with atrial fibrillation.

摘要翻译： 本发明提供了用于闭塞左心耳的装置和方法。 该装置包括尺寸适于在患者中使用的形状记忆材料的容易部署的线结构。 该装置可以制造成各种尺寸以用于各种患者。 该装置具有附着的用于覆盖左心耳的开口的材料片和用于基本上在左心耳内的固定附接的装置。 该方法包括在左心耳中部署该装置，牢固地固定装置，并且确保一片材料能够消除左心耳的开口。 这些特征被纳入改进的装置和方法中，以便更有效地帮助预防凝块形成和凝块移入或移出左心耳，以大大降低心房颤动患者中风的风险。

公开(公告)号：US08828051B2

公开(公告)日：2014-09-09

申请号：US13173702

申请日：2011-06-30

申请人： Alex Javois ,  Franz Freudenthal

发明人： Alex Javois ,  Franz Freudenthal

IPC分类号： A61B17/08 ,  A61B17/12

CPC分类号： A61B17/12122 ,  A61B17/12172 ,  A61B2017/12054

摘要： A left atrial appendage occlusion device including an occluder disk configured to substantially prevent blood from at least one of entering and exiting the left atrial appendage, a middle portion including a coiled element and a first anchoring element. The coiled element connects to the occluder disk, has a substantially constant cross section and allows for variable length, variable orientation, and/or varied angles. The first anchoring element connects to the coiled element and includes scalloped edges that are configured to anchor the occlusion device to inner walls of the left atrial appendage and reduce the risk of one of penetration and perforation of walls of the left atrial appendage. The left atrial appendage occlusion device may also include a self-centering element that connects to the occluder disk and middle portion and is configured to center the occlusion device within the orifice of the left atrial appendage.

摘要翻译： 一种左心耳闭塞装置，包括封堵器盘，其被配置为基本上防止来自进入和离开左心耳中的至少一个的血液，中间部分包括盘绕元件和第一锚定元件。 线圈元件连接到封堵器盘，具有基本上恒定的横截面并且允许可变长度，可变取向和/或变化的角度。 第一锚固元件连接到线圈元件并且包括扇形边缘，其被构造成将闭塞装置锚定到左心耳的内壁并且降低左心耳壁的穿透和穿孔之一的风险。 左心耳闭塞装置还可以包括连接到封堵器盘和中间部分的自定心元件，并且构造成将闭塞装置置于左心耳的孔内。

公开(公告)号：US20120065667A1

公开(公告)日：2012-03-15

申请号：US13173702

申请日：2011-06-30

申请人： Alex Javois ,  Franz Freudenthal

发明人： Alex Javois ,  Franz Freudenthal

IPC分类号： A61B17/08

CPC分类号： A61B17/12122 ,  A61B17/12172 ,  A61B2017/12054

摘要： A left atrial appendage occlusion device including an occluder disk configured to substantially prevent blood from at least one of entering and exiting the left atrial appendage, a middle portion including a coiled element and a first anchoring element. The coiled element connects to the occluder disk, has a substantially constant cross section and allows for variable length, variable orientation, and/or varied angles. The first anchoring element connects to the coiled element and includes scalloped edges that are configured to anchor the occlusion device to inner walls of the left atrial appendage and reduce the risk of one of penetration and perforation of walls of the left atrial appendage. The left atrial appendage occlusion device may also include a self-centering element that connects to the occluder disk and middle portion and is configured to center the occlusion device within the orifice of the left atrial appendage.

摘要翻译： 一种左心耳闭塞装置，包括封堵器盘，其被配置为基本上防止来自进入和离开左心耳中的至少一个的血液，中间部分包括盘绕元件和第一锚定元件。 线圈元件连接到封堵器盘，具有基本上恒定的横截面并且允许可变长度，可变取向和/或变化的角度。 第一锚固元件连接到线圈元件并且包括扇形边缘，其被构造成将闭塞装置锚定到左心耳的内壁并且降低左心耳壁的穿透和穿孔之一的风险。 左心耳闭塞装置还可以包括连接到封堵器盘和中间部分的自定心元件，并且构造成将闭塞装置置于左心耳的孔内。