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公开(公告)号:US20080138360A1
公开(公告)日:2008-06-12
申请号:US11661217
申请日:2005-08-29
申请人: Alexis Lasa Musacchio , Santiago Duenas Carrera , Liz Alvarez-Lajonchere Ponce de Leon , Nelson Acosta Rivero , Gillian Martinez Donato , Maria Guirola Tsibulova , Gretel Sardinas Garcia
发明人: Alexis Lasa Musacchio , Santiago Duenas Carrera , Liz Alvarez-Lajonchere Ponce de Leon , Nelson Acosta Rivero , Gillian Martinez Donato , Maria Guirola Tsibulova , Gretel Sardinas Garcia
IPC分类号: A61K39/295 , A61K39/29 , A61P35/00 , A61P31/00 , A61P1/16
CPC分类号: A61K39/095 , A61K39/12 , A61K39/29 , A61K39/292 , A61K2039/5256 , A61K2039/53 , A61K2039/54 , A61K2039/545 , A61K2039/555 , A61K2039/55505 , A61K2039/55566 , A61K2039/57 , A61K2039/70 , C12N2710/24143 , C12N2730/10134 , C12N2770/24234
摘要: A vaccine composition for the therapeutic and prophylactic treatment of Hepatitis C, containing as components the Hepatitis C virus structural proteins in certain proportions and having an enhancer effect in the development of the immune response against the Hepatitis C virus. Combined vaccines against pathogenic entities including this vaccine composition are also described.
摘要翻译: 用于治疗和预防性治疗丙型肝炎的疫苗组合物,其以特定比例含有丙型肝炎病毒结构蛋白的组分,并且在发展针对丙型肝炎病毒的免疫应答方面具有增强作用。 还描述了针对包括该疫苗组合物的致病实体的组合疫苗。
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公开(公告)号:US20050175624A1
公开(公告)日:2005-08-11
申请号:US10511384
申请日:2003-04-11
申请人: Monica Romero , Boris Ernesto Castro , Jorge Victor Cowley , Luis Enrique Molina , Omar Ocejo , Ricardo de la Caridad Rodriguez , Alexis Lasa , Ernesto Rodriguez , Dania Marcia Blomquist
发明人: Monica Romero , Boris Ernesto Castro , Jorge Victor Cowley , Luis Enrique Molina , Omar Ocejo , Ricardo de la Caridad Rodriguez , Alexis Lasa , Ernesto Rodriguez , Dania Marcia Blomquist
IPC分类号: A61K38/18 , A61K39/00 , A61K48/00 , A61P43/00 , C07K14/515 , C07K14/52 , C07K14/71 , C07K14/715 , C12N15/12
CPC分类号: C07K14/715 , A61K38/1858 , A61K38/1866 , A61K39/0005 , A61K39/0008 , A61K39/001 , A61K39/0011 , A61K48/005 , A61K2039/5256 , A61K2039/5258 , A61K2039/53 , A61K2039/55516 , A61K2039/55594 , C07K14/515 , C07K14/52 , C07K14/71
摘要: Application of oligonucleotide and polypeptide sequences of molecules of the family of the vascular permeability factor (VPF), their receptors, and co-receptors, as well as their modifications, in the active immunotherapy of pathologic entities in which course is associated to the increase of angiogenesis. These procedures can be employed in the single or combined therapy for the treatment of cancer and its metastasis, acute and chronic inflammatory processes, infectious diseases, autoimmune diseases, diabetic and newborn retinopathies, organ transplant rejection, macular degeneration, neovascular glaucoma, hemangioma, and angiofibroma, among others.
摘要翻译: 血管通透性因子(VPF)家族的分子的寡核苷酸和多肽序列在病理实体的主动免疫治疗中的应用及其修饰,其中该过程与增加相关 血管生成。 这些方法可以用于治疗癌症及其转移,急性和慢性炎症过程,感染性疾病,自身免疫性疾病,糖尿病和新生儿视网膜病变,器官移植排斥,黄斑变性,新生血管性青光眼,血管瘤和 血管纤维瘤等。
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