公开(公告)号：US08858619B2

公开(公告)日：2014-10-14

申请号：US11432838

申请日：2006-05-12

Applicant: Allen J. Tower ,  Philipp Bonhoeffer ,  Michael L. Martin

Inventor： Allen J. Tower ,  Philipp Bonhoeffer ,  Michael L. Martin

IPC: A61F2/24 ,  A61F2/958 ,  A61F2/90

CPC classification number: A61F2/2433 ,  A61F2/2412 ,  A61F2/2475 ,  A61F2/90 ,  A61F2/958

Abstract: A system for percutaneously inserting a prosthesis containing a biological replacement for a defective valve into an implantation site through a body lumen. The system contains a balloon catheter upon which a collapsable stent containing a venous valvular replacement is mounted. A protective shield is slidably mounted upon the catheter that is movable between a closed position over the balloon and an open position wherein the balloon can be inflated to expand the stent. A central lumen runs through the catheter that is formed of stainless steel. The central lumen provides a one to one torque ratio between the proximal end of the catheter and the distal end to enhance the steerability of the catheter. The vein of the replacement is reduced in thickness between 50% and 90% of its original size thereby considerably reducing the size of the replacement package when the stem is collapsed upon the balloon of the catheter.

Abstract translation: 一种用于将含有有缺陷的瓣膜的生物学替代物的假体经由体腔插入植入部位的系统。 该系统包含气囊导管，在其上安装含有静脉瓣膜置换物的可收缩支架。 保护罩可滑动地安装在导管上，该导管可在气囊上的关闭位置和打开位置之间移动，其中气囊可膨胀以使支架膨胀。 中央管腔穿过由不锈钢形成的导管。 中心腔在导管的近端和远端之间提供一到一个扭矩比，以增强导管的可操纵性。 更换的静脉厚度在其原始尺寸的50％至90％之间减小，从而当杆在导管的气囊上塌陷时大大减小了更换包装的尺寸。

公开(公告)号：US20090143728A1

公开(公告)日：2009-06-04

申请号：US11947870

申请日：2007-11-30

Applicant: Allen J. Tower

Inventor： Allen J. Tower

IPC: A61M25/10

CPC classification number: A61M25/10182 ,  A61M25/1011 ,  A61M25/10185 ,  A61M2025/1013

Abstract: A balloon catheter having a safety feature for protecting a patient during a medical procedure in the event the inflated balloon ruptures during the procedure. The catheter contains an outer balloon attached to the distal end of an insertion tube and a second inner balloon totally enclosed within the outer balloon. A vacuum is drawn on the outer balloon to evacuate the interior of the balloon and the inner balloon is then inflated to a desired operating pressure. In the event the inner balloon ruptures while inflated, the inflation fluid is fully contained within the outer balloon as well as any inner balloon fragments that are released due to the rupture.

Abstract translation: 气囊导管具有用于在手术过程中膨胀的球囊破裂的情况下在医疗过程中保护患者的安全特征。 该导管包括附接到插入管的远端的外球囊和完全封闭在外球囊内的第二内球囊。 在外球囊上抽真空以抽空气囊的内部，然后将内气囊膨胀至所需的操作压力。 在内气囊膨胀的同时，膨胀流体完全容纳在外球囊内以及由于破裂而被释放的任何内气球碎片。

公开(公告)号：US5695498A

公开(公告)日：1997-12-09

申请号：US608123

申请日：1996-02-28

Applicant: Allen J. Tower

Inventor： Allen J. Tower

IPC: A61F2/06 ,  A61F2/84 ,  A61F11/00

CPC classification number: A61F2/958

Abstract: A device for implanting a radially expandable stent that includes a balloon catheter having a balloon formed of a material having a memory so that when inflated to a first pressure the two end sections of the balloon expand to a first diameter as the waist therebetween expands to a lesser diameter. The stent is mounted over the waist section of the balloon and is thus locked between the two end sections during initial inflation to the first pressure. Once locked in place, the pressure inside the balloon is raised to a second higher level whereby the entire balloon expands to a larger diameter thus radially expanding the stent.

Abstract translation: 一种用于植入可径向扩张的支架的装置，其包括具有由具有存储器的材料形成的球囊的球囊导管，使得当膨胀至第一压力时，所述球囊的两个端部部分膨胀至第一直径， 直径较小 支架安装在气囊的腰部上，因此在初始充气到第一压力期间锁定在两个端部之间。 一旦锁定就位，气囊内的压力升高到第二较高水平，由此整个球囊膨胀到更大的直径，从而径向扩张支架。

公开(公告)号：US5352199A

公开(公告)日：1994-10-04

申请号：US68928

申请日：1993-05-28

Applicant: Allen J. Tower

Inventor： Allen J. Tower

IPC: A61B17/00 ,  A61F2/958 ,  A61M29/02 ,  A61M29/00

CPC classification number: A61M25/1002 ,  A61M29/02 ,  A61B2017/00783 ,  A61M2025/1059

Abstract: There is disclosed a balloon catheter wherein the balloon is fabricated of a high pressure, ultra-thin wall modified polyethylene terephthalate copolymer, and has a desired memorized shape. In a preferred embodiment the balloon has a central waist-like configuration suitable for valvuloplasty. The polymer can be heat-shaped and retains or memorizes a desired shape thereafter. The balloon is blow-molded and attached to a catheter for inflation through a lumen thereof. When inflated to a first low pressure it assumes the desired shape, and rounds out after a second inflating pressure is achieved.

Abstract translation: 公开了一种球囊导管，其中气囊由高压超薄壁改性聚对苯二甲酸乙二醇酯共聚物制成，并且具有所需的记忆形状。 在优选实施例中，气囊具有适于瓣膜成形术的中央腰部状构造。 聚合物可以是热形的并且之后保留或记忆所需的形状。 将气球吹塑并附着到导管以通过其内腔充气。 当膨胀到第一低压时，它呈现所需的形状，并且在达到第二充气压力之后圆整。

公开(公告)号：US5161773A

公开(公告)日：1992-11-10

申请号：US561671

申请日：1990-08-01

Applicant: Allen J. Tower

Inventor： Allen J. Tower

IPC: A61M39/06 ,  A61M39/22 ,  B21L99/00

CPC classification number: B21L99/00 ,  A61M39/0613 ,  A61M2039/0673 ,  A61M39/228

Abstract: A combination valve and clamping device is provided in which a flexible elastic inner lining is secured in a tubular outer shell having a port for introducing a fluid therebetween. A source of pressure such as a hypodermic syringe is used to cause the inner elastic sleeve to collapse and deform internally upon itself to surround and form a seal about a catheter located therein, positioning it within the shell. Alternatively, if nothing is present in the shell, the sleeve is collapsed on itself to prevent leakage of a fluid through the valve mechanism.

Abstract translation: 提供组合阀和夹紧装置，其中柔性弹性内衬固定在具有用于在其间引入流体的端口的管状外壳中。 使用诸如皮下注射器的压力来引起内弹性套筒在内部折叠和内部变形，以围绕位于其中的导管围绕并形成密封件，将其定位在壳体内。 或者，如果壳体中没有任何物体，则套筒自身折叠以防止流体通过阀机构泄漏。

公开(公告)号：US20110282198A1

公开(公告)日：2011-11-17

申请号：US12781420

申请日：2010-05-17

Applicant: Allen J. Tower

Inventor： Allen J. Tower

IPC: A61B6/00 ,  A61M25/10

CPC classification number: A61M25/007 ,  A61M25/1002 ,  A61M2025/0024 ,  A61M2025/0681 ,  A61M2025/105

Abstract: An angiographic catheter having an elongated flexible insertion tube having a cylindrical inflatable sheath circumferentially mounted thereon. The sheath contains a series of discharge ports at its distal end. A fluid is introduced into the proximal end of the sheath under sufficient pressure so that the sheath is fully inflated and fluid is discharged into a desired target area within the patients body.

Abstract translation: 一种血管造影导管，其具有细长的柔性插入管，其具有周向安装在其上的圆柱形可充气护套。 护套在其远端包含一系列排放口。 在足够的压力下将流体引入护套的近端，使得护套完全充气，并且流体被排出到患者体内的期望的目标区域内。

公开(公告)号：US5161547A

公开(公告)日：1992-11-10

申请号：US619010

申请日：1990-11-28

Applicant: Allen J. Tower

Inventor： Allen J. Tower

IPC: A61F2/06 ,  A61F2/88

CPC classification number: A61F2/88

Abstract: An improved radially expandable stent formed from a fine wire bent into a serpentine flat ribbon which is wound around a mandrel into a cylindrical sleeve for mounting on a balloon catheter for transluminal insertion in a vessel such as a blood vessel is provided. A very small diameter fine platinum wire is used to form the basic cylindrical sleeve and it is welded to a pigtail of the wire forming the sleeve to provide longitudinal stablility.

Abstract translation: 提供了一种改进的可径向扩张的支架，其由弯曲成蛇形扁平带的细线形成，其被卷绕在心轴上成圆柱形套筒，用于安装在气囊导管上用于腔内插入血管如血管中。 使用非常小直径的细铂丝来形成基本的圆柱形套筒，并且将其焊接到形成套筒的线的尾纤以提供纵向稳定性。

公开(公告)号：US5389106A

公开(公告)日：1995-02-14

申请号：US145435

申请日：1993-10-29

Applicant: Allen J. Tower

Inventor： Allen J. Tower

IPC: A61F2/06 ,  A61F2/88 ,  A61M29/00

CPC classification number: A61F2/88

Abstract: There is disclosed a radially expandable stent for intravascular implantation comprising a distensible frame and an impermeable deformable membrane interconnecting portions of the frame to form an impermeable exterior wall. The membrane is formed of a synthetic non-latex, non-vinyl polymer, and the frame comprises a fine wire of annealed platinum. The comprises a plurality of helically aligned circumferential sections including two end sections and a plurality of intermediate sections that define a cylinder having a longitudinal axis, the cylinder being formed of a continuous wire with the circumferential sections being spaced along the axis in abutting contact. Each of the circumferential sections have expandable segments that impart radial expandability to the sections. The expandable segments are tear-drop shaped elements that are alternately inverted about the circumferential sections, each element containing a base and a pair of legs that come together at a common apex when the stent is in an unexpanded condition. One of the end sections has a pigtail that is passed back along the circumferential sections and is joined to the other end section to prevent axial expansion of the expanded during radial expansion.

Abstract translation: 公开了一种用于血管内植入的可径向扩张的支架，其包括可扩张的框架和互连框架部分以形成不可渗透的外壁的不可渗透的可变形膜。 该膜由合成非胶乳非乙烯基聚合物形成，并且该框架包括退火铂的细线。 包括多个螺旋对准的圆周部分，其包括两个端部部分和多个中间部分，所述多个中间部分限定具有纵向轴线的圆柱体，所述圆柱体由连续的线形成，所述圆周部分沿着所述轴线邻接接触而间隔开。 每个圆周部分都具有向径向扩张的部分。 可扩展段是泪滴形元件，其围绕圆周部分交替倒置，每个元件包含基部和一对支腿，当支架处于未膨胀状态时，它们在共同的顶点处汇合在一起。 一个端部部分具有沿着周向部分返回的引线，并且连接到另一端部分以防止在径向膨胀期间膨胀的轴向膨胀。

公开(公告)号：US5087247A

公开(公告)日：1992-02-11

申请号：US574370

申请日：1990-08-28

Applicant: Joseph B. Horn ,  Allen J. Tower ,  James F. King

Inventor： Joseph B. Horn ,  Allen J. Tower ,  James F. King

IPC: A61M29/02

CPC classification number: A61M25/104 ,  A61M2025/0177 ,  A61M2025/1097

Abstract: Balloon perfusion catheter having a flexible elongated shaft from which a perfusion shaft and an inflation shaft outwardly extend. An angioplasty balloon is circumferentially mounted around the perfusion shaft. The inflation shaft distal end is located at the balloon proximal end. Openings in the perfusion shaft both proximal and distal to the balloon permit blood flow through artery during balloon inflation.

Abstract translation: 气囊灌注导管具有柔性细长轴，灌注轴和充气轴从该轴伸出。 血管成形术球囊围绕灌注轴周向安装。 充气轴远端位于球囊近端。 在球囊近端和远端的灌注轴中的开口在球囊充气期间允许血液通过动脉流动。

公开(公告)号：US5002559A

公开(公告)日：1991-03-26

申请号：US443387

申请日：1989-11-30

Applicant: Allen J. Tower

Inventor： Allen J. Tower

IPC: A61M25/00 ,  A61M29/02

CPC classification number: A61M25/1027 ,  A61M25/104 ,  A61M2025/1093

Abstract: A PTCA catheter is provided in which the extreme distal end is reduced to a diameter of 3 thousandths of an inch and enclosed in a coiled spring which is welded to the guidewire of the catheter at its tip and at a thicker 8 thousandths diameter portion of the guidewire to increase the strength of the tip and reduce breakage when inserted in a coronary artery. A dual lumen catheter body is provided at the proximal end for capturing and actuating the guidewire and for inflating the balloon at the distal end.

Abstract translation: 提供了一种PTCA导管，其中最远端被减小到千分之三千分之一的直径，并且包围在螺旋弹簧中，该螺旋弹簧在其尖端处焊接到导管的导丝并且在其直径较大的第八千分之一直径 导丝以增加尖端的强度并且当插入冠状动脉时减少断裂。 在近端处设置双腔导管体，用于捕获和致动导丝，并在远端使气囊膨胀。