专利检索 ap:"Amy E. Beilstein" 第 1 页

1.

发明授权
Methods of synthesis of halogen base-modified oligonucleotides and subsequent labeling with a metal-catalyzed reaction 失效
标题翻译：合成卤素碱基修饰寡核苷酸的方法，随后用金属催化反应进行标记

公开(公告)号：US06288221B1

公开(公告)日：2001-09-11

申请号：US09377612

申请日：1999-08-19

申请人： Mark W. Grinstaff , Amy E. Beilstein , Shoeb I. Khan

发明人： Mark W. Grinstaff , Amy E. Beilstein , Shoeb I. Khan

IPC分类号： C07H2100

CPC分类号： C07H19/06 , C07H19/10 , C07H21/00

摘要： The present invention provides metal-containing purines, pyrimidines, nucleosides, nucleotides and oligonucleotides; including phosphoramidite and photolabile derivatives thereof, including methods of making and method of using same. The present invention provides a method for detection of nucleic acid sequences via electrochemical or photochemical means.

摘要翻译： 本发明提供含金属嘌呤，嘧啶，核苷，核苷酸和寡核苷酸; 包括亚磷酰胺及其不透光衍生物，包括制备方法及其使用方法。本发明提供了通过电化学或光化学方法检测核酸序列的方法。