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    NEW USE FOR CANNABINOID-CONTAINING PLANT EXTRACTS
    1.
    发明申请
    NEW USE FOR CANNABINOID-CONTAINING PLANT EXTRACTS 审中-公开
    用于含CANNABINOID的植物提取物的新用途

    公开(公告)号：US20100249223A1

    公开(公告)日：2010-09-30

    申请号：US12596500

    申请日：2008-04-17

    申请人： Vincenzo Di Marzo ,  Luciano De Petrocellis ,  Aniello Schiano Moriello

    发明人： Vincenzo Di Marzo ,  Luciano De Petrocellis ,  Aniello Schiano Moriello

    IPC分类号： A61K31/352 ,  A61K31/05 ,  A61P25/00 ,  A61P29/00

    CPC分类号： A61K36/185 ,  A61P35/00

    摘要： The present invention relates to the use of cannabinoid-containing plant extracts in the prevention or treatment of diseases or conditions that are alleviated by blockade of one or more types of TRP channel. Preferably the subset of TRP channel that is blockaded is the TRPA channel. More preferably the TRPA channel is the TRPA1 channel. Preferably the diseases or conditions to be prevented or treated include: neuropathic pain, inflammation or vasoconstriction. Alternatively the TRP channel that is blockaded is the TRPM channel. More preferably the TRPM channel is the TRPM8 channel. Preferably the diseases or conditions to be prevented or treated are cancer. More preferably the cancers to be treated include: cancer of the prostate, cancer of the breast, cancer of the colon, cancer of the lung or cancer of the skin. Alternatively the TRP channel that is blockaded is the TRPV channel. More preferably the TRPV channel is the TRPV1 channel. Preferably the diseases or conditions to be prevented or treated include neuropathic pain, inflammation or vasoconstriction.

    摘要翻译： 本发明涉及含有大麻素的植物提取物在预防或治疗通过封锁一种或多种TRP通道而减轻的疾病或病症中的用途。 优选地，阻塞的TRP信道的子集是TRPA信道。 更优选地，TRPA信道是TRPA1信道。 优选地，要预防或治疗的疾病或病症包括：神经性疼痛，炎症或血管收缩。 或者，阻塞的TRP信道是TRPM信道。 更优选地，TRPM信道是TRPM8信道。 优选地，预防或治疗的疾病或病症是癌症。 更优选地，待治疗的癌症包括：前列腺癌，乳腺癌，结肠癌，肺癌或皮肤癌。 或者，阻塞的TRP信道是TRPV信道。 更优选地，TRPV信道是TRPV1信道。 优选地，要预防或治疗的疾病或病症包括神经性疼痛，炎症或血管收缩。